Displaying drugs 2551 - 2575 of 3248 in total
Chlorthalidone
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide ... 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and heart ... Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through …
Matched Mixtures name: … TRI NORMIN 50 ... TENORET 50 TABLET ... PRETENOL C 50 TABLET …
Matched Categories: … Thiazide-like Diuretic ... Sodium Chloride Symporter Inhibitors ... chlortalidone and potassium ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Products: … HYGROTON 50 ... HIGROTON 50 ... CLORTAX 50 MG TABLETAS …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and heart ... Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through …
Matched Mixtures name: … TRI NORMIN 50 ... TENORET 50 TABLET ... PRETENOL C 50 TABLET …
Matched Categories: … Thiazide-like Diuretic ... Sodium Chloride Symporter Inhibitors ... chlortalidone and potassium ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Products: … HYGROTON 50 ... HIGROTON 50 ... CLORTAX 50 MG TABLETAS …
Dihydrostreptomycin
Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl …
Matched Iupac: … N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl ... )-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl …
Matched Iupac: … N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl ... )-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy …
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, ... count, and neuropsychiatric effects [A19635]. ... Sofosbuvir is metabolized into its active form as the antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5' …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir, velpatasvir and voxilaprevir …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy …
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, ... count, and neuropsychiatric effects [A19635]. ... Sofosbuvir is metabolized into its active form as the antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5' …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir, velpatasvir and voxilaprevir …
(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
Experimental
Matched Name: … (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Betazole
A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 2-(1H-pyrazol-5-yl)ethanamine …
Matched Iupac: … 2-(1H-pyrazol-5-yl)ethan-1-amine …
Matched Salts name: … Betazole hydrochloride …
Matched Iupac: … 2-(1H-pyrazol-5-yl)ethan-1-amine …
Matched Salts name: … Betazole hydrochloride …
Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Synonyms: … 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil …
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina ... It is enriched in the liver, egg yolks, and the fat component of dairy products. …
Matched Mixtures name: … 50 Plus ... Men's 50+ ... Adult Formula 50+ …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … RETIBLAN 50 CAPSULAS ... VITAMIN A-POS 250 IU 5 GR GOZ MERHEMI …
Matched Mixtures name: … 50 Plus ... Men's 50+ ... Adult Formula 50+ …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … RETIBLAN 50 CAPSULAS ... VITAMIN A-POS 250 IU 5 GR GOZ MERHEMI …
(5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL
Experimental
Matched Name: … (5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL …
Matched Iupac: … [5-(3-{5-[(piperidin-1-yl)methyl]-1H-indol-2-yl}-1H-indazol-6-yl)-2H-1,2,3-triazol-4-yl]methanol …
Matched Iupac: … [5-(3-{5-[(piperidin-1-yl)methyl]-1H-indol-2-yl}-1H-indazol-6-yl)-2H-1,2,3-triazol-4-yl]methanol …
Esuberaprost
Investigational
Matched Synonyms: … 1e,3s,4s)-3-hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro-1h-cyclopenta(b)(1)benzofuran-5- ... 1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4- …
Matched Salts cas: … 152695-53-9 …
Matched Salts name: … Esuberaprost Sodium …
Matched Salts cas: … 152695-53-9 …
Matched Salts name: … Esuberaprost Sodium …
(5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one
Experimental
Matched Name: … (5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one …
Matched Iupac: … (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(2-hydroxypropan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol …
Matched Iupac: … (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(2-hydroxypropan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol …
5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide
Experimental
Matched Name: … 5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide …
Matched Iupac: … 5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N,2,4-trimethyl-1H-pyrrole-3-carboxamide …
Matched Iupac: … 5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N,2,4-trimethyl-1H-pyrrole-3-carboxamide …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5 …
Matched Iupac: … (1'R,3R,10'S)-5-(2,2,2-trifluoroethyl)-5'-[(1E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-en-1-yl]spiro …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
Matched Iupac: … (1'R,3R,10'S)-5-(2,2,2-trifluoroethyl)-5'-[(1E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-en-1-yl]spiro …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
Experimental
Matched Name: … 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine …
Matched Iupac: … 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine …
N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …
5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione
Experimental
Matched Name: … 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione …
Matched Iupac: … 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-4,7-dihydro-1H-indole-4,7-dione …
Matched Iupac: … 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-4,7-dihydro-1H-indole-4,7-dione …
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
Experimental
Matched Name: … 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}({hydroxy …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}({hydroxy …
5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid
Experimental
Matched Name: … 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
2'-O-[1-ethyl-1H-imidazol)] thymidine-5'-monophosphate
Experimental
Matched Name: … 2'-O-[1-ethyl-1H-imidazol)] thymidine-5'-monophosphate …
Matched Iupac: … {[(2R,3R,4R,5R)-3-hydroxy-4-[2-(1H-imidazol-1-yl)ethoxy]-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin …
Matched Iupac: … {[(2R,3R,4R,5R)-3-hydroxy-4-[2-(1H-imidazol-1-yl)ethoxy]-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin …
N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE
Experimental
Matched Name: … N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic …
1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID
Experimental
Matched Name: … 1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID …
Matched Iupac: … N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid …
Matched Iupac: … N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid …
5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole
Experimental
Matched Name: … 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole …
Matched Iupac: … 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole …
Matched Iupac: … 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole …
4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid …
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid …
5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile
Experimental
Matched Name: … 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile …
Matched Iupac: … 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile …
Matched Iupac: … 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile …
ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE
Experimental
Matched Name: … ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE …
Matched Iupac: … (2S)-2-[(2-acetyl-5-methylphenyl)amino]-2-(2,6-dichlorophenyl)acetamide …
Matched Iupac: … (2S)-2-[(2-acetyl-5-methylphenyl)amino]-2-(2,6-dichlorophenyl)acetamide …
Displaying drugs 2551 - 2575 of 3248 in total