Displaying drugs 251 - 275 of 312 in total
MS1901
Investigational
Matched Synonyms: … Thrombin-preconditioned allogeneic Wharton's Jelly-derived mesenchymal stem cells …
EDIT-301
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Matched Description: … EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
VOR33
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
OTL-203
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
CYNK-101
CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Investigational
Matched Synonyms: … allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that …
Matched Description: … CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy …
Matched Description: … CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy …
RP-L201
Investigational
Matched Synonyms: … Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene …
Nalotimagene carmaleucel
Investigational
Matched Synonyms: … Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo …
Spanlecortemlocel
Investigational
Matched Synonyms: … ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 …
Mozafancogene autotemcel
RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …
Taniraleucel
Investigational
Matched Synonyms: … Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. …
Voacamine
Voacamine is an alkaloid isolated from the bark of the Pescheria fuchsiae folia tree. It is an antimalarial drug approved for use in several African countries. Voacamine is also under investigation for use in modulating multidrug-resistance in tumor cells.
Experimental
Matched Description: … Voacamine is an alkaloid isolated from the bark of the _Pescheria fuchsiae folia_ tree. …
KW-7158
KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the bladder). The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels...
Investigational
Matched Description: … A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root …
Efprezimod alfa
CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.
Investigational
Matched Description: … CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem …
CTCE-0214
CTCE-0214 is a stable peptide agonist of stromal cell-derived factor-1 (SDF-1), a key signaling molecule in the proliferation, homing, engraftment and expansion of hematopoietic stem cells and white blood cells.
Investigational
Matched Description: … , a key signaling molecule in the proliferation, homing, engraftment and expansion of hematopoietic stem …
ReN001
ReN001 is a clonal human neural stem cell line developed for clinical use in the treatment of stable disability after stroke. ReN001 a strong candidate for one of the first cell-based IND applications to be submitted to the Food and Drug Administration in the United States for consideration for the...
Investigational
Matched Description: … ReN001 is a clonal human neural stem cell line developed for clinical use in the treatment of stable …
Carlecortemcel-L
Investigational
Celastrol
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Description: … Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_. …
NSI-566
NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells. Developed by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).
Investigational
Matched Description: … NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells. …
Ethylmorphine
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Dilanubicel
Dilanubicel consists of ex vivo expanded hematopoietic stem and progenitor cells.
Investigational
Matched Description: … Dilanubicel consists of ex vivo expanded hematopoietic stem and progenitor cells. …
ASP-7317
ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells.
Investigational
Matched Description: … ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells. …
GIVI-MPC
GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells.
Investigational
Matched Description: … GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells …
TBX-1400
TBX-1400 consists of human donor hematopoietic stem and progenitor cells.
Investigational
Matched Description: … TBX-1400 consists of human donor hematopoietic stem and progenitor cells. …
Displaying drugs 251 - 275 of 312 in total