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Displaying drugs 251 - 275 of 708 in total
Uridine triacetate
Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Synonyms: … Tri-O-acetyluridine ... 2',3',5'-tri-O-acetyluridine …
Matched Description: … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …
Matched Description: … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate ... 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide …
Matched Description: … of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. ... , often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. ... It is available as a tablet and is usually dosed twice daily. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. ... , often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. ... It is available as a tablet and is usually dosed twice daily. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Delolimogene mupadenorepvec
Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …
Cotsiranib
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … factor and an elastin-like polypeptide drug carrier. ... Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) ... designed to down-regulate the expression of EVI1 oncogene in cancer cells. …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) ... designed to down-regulate the expression of EVI1 oncogene in cancer cells. …
Exenatide
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … Exenatide was given FDA approval on April 28, 2005[L6106]. ... It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Fluids and Secretions ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Matched Categories: … Fluids and Secretions ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Synthetic camphor
Approved
Experimental
Matched Synonyms: … 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one ... (1RS,4RS)-1,7,7-trimethylbicyclo(2.2.1)heptan-2-one …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Mixtures name: … CAMPHOR, EUCALYPTUS OIL and MENTHOL ... Pain ReliefRoll On Roll On ... OH BALM …
Matched Products: … O24 Essential Oil Pain Relieving ... Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Mixtures name: … CAMPHOR, EUCALYPTUS OIL and MENTHOL ... Pain ReliefRoll On Roll On ... OH BALM …
Matched Products: … O24 Essential Oil Pain Relieving ... Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers …
Chenopodium album pollen
Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Description: … Chenopodium album pollen is the pollen of the Chenopodium album plant. …
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Matched Description: … These are heat inactivated and purified. …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this ... TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. ... various degrees of organ damage. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
Matched Description: … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this ... TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. ... various degrees of organ damage. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Description: … Nicotine is also important medically because of its presence in tobacco smoke. ... the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … Care One Nicotine ... Up and Up Nicotine ... Up and Up nicotine …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … Care One Nicotine ... Up and Up Nicotine ... Up and Up nicotine …
Fibrinogen human
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … , including afibrinogenemia and hypofibrinogenemia. ... It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL …
N-[O-Phosphono-Pyridoxyl]-Isoleucine
Experimental
Matched Name: … N-[O-Phosphono-Pyridoxyl]-Isoleucine …
5'-O-(L-Threonylsulfamoyl)adenosine
Experimental
Matched Name: … 5'-O-(L-Threonylsulfamoyl)adenosine …
Matched Iupac: … ,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-hydroxybutan-1-one …
Matched Iupac: … ,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-hydroxybutan-1-one …
GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE
Experimental
Matched Name: … GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE …
Matched Iupac: … [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …
Matched Iupac: … [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …
Methyl salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Synonyms: … Oil of wintergreen ... Betula oil ... Gaultheria oil …
Matched Description: … It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many ... species of plants, particularly wintergreens. …
Matched Mixtures name: … Walgreens Cool and Heat Muscle and Joint Relief ... Pain ReliefRoll On Roll On ... Up and Up Pain …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Neuro Max Pain and Muscle Relief Gel ... Dermorub Liniment Muscle and Joint ... Flexitol Foot and Knee Pain Relief …
Matched Description: … It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many ... species of plants, particularly wintergreens. …
Matched Mixtures name: … Walgreens Cool and Heat Muscle and Joint Relief ... Pain ReliefRoll On Roll On ... Up and Up Pain …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Neuro Max Pain and Muscle Relief Gel ... Dermorub Liniment Muscle and Joint ... Flexitol Foot and Knee Pain Relief …
Salsalate
Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been...
Approved
Matched Synonyms: … o-Salicylsalicylic acid ... O-Salicylcylsalicylsäure …
Matched Description: … synthesis and release of prostaglandins. ... Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of ... A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis …
Matched Categories: … Salicylic Acid and Derivatives …
Matched Description: … synthesis and release of prostaglandins. ... Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of ... A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis …
Matched Categories: … Salicylic Acid and Derivatives …
Arbutin
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … hydroquinone O-β-D-glucopyranoside ... Hydroquinone-O-beta-D-glucopyranoside …
Matched Description: … Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly ... Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes [A27248], and the inhibition ... and [DB09526] [F43]. …
Matched Mixtures name: … D-one By Tamdoan Bb Light ... D-one By Tamdoan Bb Medium ... D-one By Tamdoan Sunscreen 50 …
Matched Description: … Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly ... Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes [A27248], and the inhibition ... and [DB09526] [F43]. …
Matched Mixtures name: … D-one By Tamdoan Bb Light ... D-one By Tamdoan Bb Medium ... D-one By Tamdoan Sunscreen 50 …
4-(Hydrogen sulfate)-beta-D-galactopyranose
Experimental
Matched Synonyms: … 4-O-Sulfo-β-D-galactopyranose …
Foslevodopa
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … 3-hydroxy-O-phosphono-L-tyrosine …
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and ... Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and ... Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH ... N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN AVERAGE OFAPPROXIMATELY ... -METHOXYPOLY(O …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Suratadenoturev
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human ... DNA (recombinant human telomerase-specific replication-competent oncolytic adenovirus 5 vector OBP-301 ... telomerase reverse transcriptase (hTERT) and IRES, respectively. …
Butylene glycol
Approved
Experimental
Matched Products: … Dr.g Lock and More Nourishing Mask ... Dr.g Lock and More Sensi Calming Mask ... PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU …
Clotrimazole
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Synonyms: … 1-(o-Chlorotrityl)imidazole ... 1-(o-Chloro-α,α-diphenylbenzyl)imidazole …
Matched Description: … The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain ... diseases such as sickle cell disease, malaria and some cancers [A174094]. ... It is available in various preparations, including creams, pessaries, and troche formulations (slowly …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … combinations of imidazole derivatives ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Fortinia OF ... GYNOKIT ® ONE ... Olp Clotrimazole …
Matched Description: … The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain ... diseases such as sickle cell disease, malaria and some cancers [A174094]. ... It is available in various preparations, including creams, pessaries, and troche formulations (slowly …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … combinations of imidazole derivatives ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Fortinia OF ... GYNOKIT ® ONE ... Olp Clotrimazole …
Displaying drugs 251 - 275 of 708 in total