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Displaying drugs 251 - 275 of 724 in total

Etigilimab

Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized ... mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32 .kappa …
Matched Description: … Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab ... in Subjects With Locally Advanced or Metastatic Tumors.). …

Tarlatamab

Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … [L50743,A263808] Its bispecificity causes T-cell activation, the release of inflammatory cytokines, and ... and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed ... across various SCLC disease stages and treatment statuses. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Water

Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … rain, and is the major constituent of the fluids of organisms. ... As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected ... Water is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with …
Matched Mixtures name: … Oil ... Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces …
Matched Products: … Oil ... Roll-On ... Ori-power …

Cetirizine

Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems ... , and up to 30%, according to self-reported nasal symptoms. ... various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms [ …
Matched Mixtures name: … ZYRTEC D Allergy and Congestion ... Cetirizine HCl and Pseudoephedrine HCl ER ... Wal Zyr D Allergy and Congestion …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … INCIDAL - OD ... Our Family Childrens Cetirizine ... SIMTEC TABLET 10MG (OTC) …

Elapegademase

Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH ... N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN AVERAGE OFAPPROXIMATELY ... -METHOXYPOLY(O …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Hydroxyproline

Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved...
Experimental
Matched Description: … Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. ... It is found in collagen and as such it is common in many gelatin products. …
Matched Mixtures name: … The History Of Whoo Gongjinhyang Mi Pact 2 ... The History Of Whoo Gongjinhyang Mi Pact 1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … O Hui Wrinkle Science Wrinkle Repair ... The History of Whoo Bichup Ja Saeng Essence ... O Hui Wrinkle Science Deep Wrinkle Treatment …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. ... Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may …
Matched Mixtures name: … Swiss One Multivitamin and Mineral Caplet ... Classic Swiss One 10 Multivitamin and Mineral Tab ... Potassium and Iodine Tab …
Matched Categories: … Diet, Food, and Nutrition ... Antiseptics and Disinfectants ... Herbs and Natural Products …
Matched Products: … OQ SEPTIC ® ... Tincture Of Iodine 5% ... XENETIX 300-50ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1 ... It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). …
Matched Mixtures name: … Oti-sol ... Gold Bond Pain and Itch ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... LYSOL Healthy Touch Aloe Vera And Vitamin E with Moisturizers …

Minoxidil

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents ... Arteriolar Smooth Muscle, Agents Acting On …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …

Pyrethrum extract

Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids ... Pyrethrins component of rid mousse …
Matched Description: … The active compound is absorbed by the lice and destroys them by acting on their nervous systems but ... Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... is thought to exert minimal effect on humans. …
Matched Mixtures name: … Care One Lice Killing ... Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Acapatamab

Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and …
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …

Lorigerlimab

Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND ... MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND …
Matched Description: … or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer). ... Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … and emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose is a hydrophilic white powder in pure form and dissolves in cold (but not in hot) water …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

Famotidine

Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … [A189462] Famotidine is used in various over-the-counter and off-label uses. ... gastroesophageal reflux disease (GERD), in adults and children. ... [ranitidine] on a weight basis. …
Matched Mixtures name: … Care One Acid Reducer and Antacid Dual Action ... Care One Acid Reducer plus Antacid Dual Action ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Care One Acid Reducer Original Strength ... Up and Up Famotidine ... Berkley and Jensen Famotidine …

Fentiazac

Experimental
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … O-FLAM …

Garcinia gummi-gutta fruit

Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Matched Description: … Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. …

DCLL-9718S

DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer ... THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine ... DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Bismuth subsalicylate

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxy-benzo[1,3,2]dioxabismin-4-one …
Matched Iupac: … 2-hydroxy-2H,4H-benzo[d]1,3-dioxa-2-bismacyclohexan-4-one …
Matched Description: … treatment of patients with _H. pylori_ infection and duodenal ulcer disease. ... Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. ... ], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ for …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …

Tepilamide fumarate

Investigational
Matched Synonyms: … 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Synonyms: … O-benzhydryldimethylaminoethanol …
Matched Description: … seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. ... has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold ... While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine …
Matched Mixtures name: … Complete One Cold and Flu PE Night ... Care One Pain Relief and Pain Relief PM ... Care One Flu and Severe Cold and Cough Nighttime …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ORA ALERGI ... NERVO OPT N ... On The GO-Dose …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( ... [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …

Dabocemagene autoficel

Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND ... SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER THE CONTROL OF …
Matched Description: … ., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa …

Tocotrienol

Tocotrienol has been investigated for the treatment of Cholesterol Lowering.
Investigational
Matched Iupac: … 2-methyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-1-benzopyran-6-ol …
Matched Description: … Tocotrienol has been investigated for the treatment of Cholesterol Lowering. …
Matched Categories: … Diet, Food, and Nutrition ... Compounds used in a research, industrial, or household setting …
Matched Products: … NATRIÉO TRI-E TOCOTRIENOLS (50MG) SOFTGEL CAPSULE …

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation ... Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. …
Matched Mixtures name: … DESENFRIOL-ON GRAGEAS REPETABS ... Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief ... Berkley and Jensen Allergy Relief …

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Synonyms: … Wool oil ... Lanolin oil …
Matched Description: … Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … Optilube Ont ... Therapeutic Bath Oil ... A and D Diaper Rash and Skin Protectant …
Matched Categories: … Basic Ointments and Protectants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Displaying drugs 251 - 275 of 724 in total