Displaying drugs 2976 - 3000 of 3303 in total
2'-deoxyuridine 5'-alpha,beta-imido-diphosphate
Experimental
Matched Name: … 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino]phosphonic acid …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino]phosphonic acid …
5-Alpha-Androstane-3-Beta,17beta-Diol
Experimental
Matched Name: … 5-Alpha-Androstane-3-Beta,17beta-Diol …
Naphazoline
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Salts name: … Naphazoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Naphazoline Hydrochloride …
Matched Mixtures name: … Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Salts name: … Naphazoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Naphazoline Hydrochloride …
Glumetinib
Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … 1h-pyrazol-4-yl)-1-((6-(1-methyl-1h-pyrazol-4-yl)imidazo(1,2-a)pyridin-3-yl)sulfonyl)-1h-pyrazolo(4,3-b)pyridine …
Matched Description: … Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety …
Matched Description: … Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety …
MK-7288
Investigational
Matched Synonyms: … Spiro(cyclohexane-1,5'(7'h)-furo(3,4-b)pyridine)-4-carboxamide, 2'-methoxy-n-methyl-7'-oxo-n-(2-(1-piperidinyl …
Matched Iupac: … 1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-[2-(piperidin-1-yl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine …
Matched Iupac: … 1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-[2-(piperidin-1-yl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine …
2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate
Experimental
Matched Name: … 2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate …
Matched Iupac: … tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Iupac: … tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino](hydroxy)phosphoryl}oxy)phosphonic acid …
7-Alpha-D-Ribofuranosyl-Purine-5'-Phosphate
Experimental
Matched Name: … 7-Alpha-D-Ribofuranosyl-Purine-5'-Phosphate …
Matched Iupac: … {[(2R,3S,4R,5S)-3,4-dihydroxy-5-(7H-purin-7-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4R,5S)-3,4-dihydroxy-5-(7H-purin-7-yl)oxolan-2-yl]methoxy}phosphonic acid …
N-alpha-Acetyl-3,5-diiodotyrosyl-D-threonine
Experimental
Matched Name: … N-alpha-Acetyl-3,5-diiodotyrosyl-D-threonine …
Matched Iupac: … (2R,3R)-2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]-3-hydroxybutanoic acid …
Matched Iupac: … (2R,3R)-2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]-3-hydroxybutanoic acid …
Alpha-D-Glucose-1-Phosphate-6-Vanadate
Experimental
Matched Name: … Alpha-D-Glucose-1-Phosphate-6-Vanadate …
5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE
Experimental
Matched Name: … 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE …
Matched Iupac: … 9bS,11aS)-1-acetyl-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-oxobutanoic acid …
Matched Iupac: … 9bS,11aS)-1-acetyl-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-oxobutanoic acid …
Mitoxantrone
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Salts name: … Mitoxantrone hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitoxantrone Hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitoxantrone Hydrochloride …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nortriptyline Hydrochloride …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nortriptyline Hydrochloride …
Fenthion
Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase...
Vet approved
Matched Synonyms: … Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-(methylthio)phenyl) ester …
Matched Description: … Fenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide. ... States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and …
Matched Description: … Fenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide. ... States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and …
Pabinafusp alfa
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
MMDA
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Vardenafil
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial ... cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis …
Matched Salts name: … Vardenafil hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Vardenafil hydrochloride ... Vardenafil Hydrochloride …
Matched Salts name: … Vardenafil hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Vardenafil hydrochloride ... Vardenafil Hydrochloride …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornase alpha …
Matched Description: … The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Matched Description: … The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine
Experimental
Matched Name: … gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine …
Matched Iupac: … amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Matched Iupac: … amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … alpha-2b) gene under the control of the cytomegalovirus (cmv) immediate-early enhancer/promoter ... Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy …
Vorapaxar
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro ... Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
North-methanocarbathymidine
Investigational
Matched Synonyms: … .,2.alpha.,4.beta.,5.alpha ... 2,4(1h,3h)-pyrimidinedione, 1-(4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl-, (1s-(1.alpha …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
2-[(2-methoxy-5-methylphenoxy)methyl]pyridine
Experimental
Matched Name: … 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine …
Matched Iupac: … 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine …
Matched Iupac: … 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine …
4-[(5-methoxy-2-methylphenoxy)methyl]pyridine
Experimental
Matched Name: … 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine …
Matched Iupac: … 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine …
Matched Iupac: … 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine …
AMY-101
AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis).
Investigational
Matched Synonyms: … S3,S13-Cyclo(D-tyrolsyl-L-isoleucyl-L-cysteinyl-L-valyl-1-methyl-L-tryptophyl-L-glutaminyl-L-aspartyl-L-tryptophyl-N-methyl-L-glycyl-L-alanyl-L-histidyl-L-arginyl-L-cysteinyl-N-methyl-L-isoleucinamide …
Matched Iupac: … decaoxo-31-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decaazacyclopentatriacontan-22-yl]acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … decaoxo-31-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decaazacyclopentatriacontan-22-yl]acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
4-[3-carboxymethyl-3-(4-phosphonooxy-benzyl)-ureido]-4-[(3-cyclohexyl-propyl)-methyl-carbamoyl]butyric acid
Experimental
Matched Name: … 3-carboxymethyl-3-(4-phosphonooxy-benzyl)-ureido]-4-[(3-cyclohexyl-propyl)-methyl-carbamoyl]butyric acid …
Matched Iupac: … {[4-(phosphonooxy)phenyl]methyl})carbamoyl]amino}-4-[(3-cyclohexylpropyl)(methyl)carbamoyl]butanoic acid …
Matched Iupac: … {[4-(phosphonooxy)phenyl]methyl})carbamoyl]amino}-4-[(3-cyclohexylpropyl)(methyl)carbamoyl]butanoic acid …
Displaying drugs 2976 - 3000 of 3303 in total