Displaying drugs 3076 - 3100 of 3953 in total
Genz-10850
Experimental
BZL101
BZL101 is an oral drug designed for the treatment of advanced breast cancer with a novel mechanism of action. BZL101 targets diseased cells while leaving normal cells healthy and intact.
Investigational
ICA-105665
ICA-105665 is a novel small molecule compound for the treatment of epilepsy. It is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy. In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain.
Investigational
JAG101
Investigational
Gam-COVID-Vac
Gam-COVID-Vac was created by Gamaleya Research Institute of Epidemiology and MIcrobiology in Russia. The vaccine candidate is a heterologous COVID-19 vaccine containing two components, recombinant adenovirus type 26 (rAd26) vector and recombinant adenovirus type 5 (rAd5) vector which both carry the SARS-CoV-2 spike glycoprotein. The vaccine is offered in both...
Investigational
Matched Description: … Phase 1/2 human trials with 76 participants evaluated the safety, tolerability, and immunogenicity of ... type 26 (rAd26) vector and recombinant adenovirus type 5 (rAd5) vector which both carry the SARS-CoV ... The vaccine candidate is a heterologous COVID-19 vaccine containing two components, recombinant adenovirus …
Latrunculin A
Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic spindle formation and thus cell replication.
Experimental
Fresolimumab
Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis.
Investigational
CVnCoV Vaccine
The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities...
Investigational
Matched Categories: … Recombinant Proteins …
Transcrocetinate
Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Investigational
Ipafricept
Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors).
Investigational
Matched Categories: … Recombinant Proteins …
Nevanimibe
Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
Investigational
M-701
M-701 is a recombinant anti-EpCAM/CD3 bispecific antibody.
Investigational
Matched Description: … M-701 is a recombinant anti-EpCAM/CD3 bispecific antibody. …
DOTMP SM-153
Investigational
Matched Iupac: … (153Sm)samarium(3+) hydrogen {[4,7-bis(hydrogen phosphonatomethyl)-10-(phosphonomethyl)-1,4,7,10-tetraazacyclododecan …
Tricarbonyl(1,10-phenanthroline)rhenium(1+)
Experimental
Vurolenatide
Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN.
Investigational
Matched Description: … Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN. …
Rocakinogene sifuplasmid
Rocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma (GBM)).
Investigational
Matched Categories: … Recombinant Proteins …
SMART101
SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
Investigational
Matched Description: … SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors …
RO7200220
RO7200220 is a recombinant fully humanized anti-IL 6 monoclonal antibody.
Investigational
Matched Description: … RO7200220 is a recombinant fully humanized anti-IL 6 monoclonal antibody. …
NU1025
Experimental
AT1022
AT1022 is a hydromorphone skin patch designed to provide rapid and sustained delivery of a potent opiate for the management of severe pain.
AT1022 incorporates PassPort(TM) system, developed to deliver protein and peptide drugs, small-molecule drugs, genes and vaccines across the skin for local and systemic effect.
Investigational
OMS-103HP
OMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
Investigational
Tegavivint
Investigational
Matched Iupac: … N-[2,7-bis({[(3R,5S)-3,5-dimethylpiperidin-1-yl]sulfonyl})-10-(hydroxyimino)-9,10-dihydroanthracen-9- …
Methyl (2S)-2-[[2-[(3R)-1-carbamimidoylpiperidin-3-yl]acetyl]amino]-3-[4-(2-phenylethynyl)phenyl]propanoate
This solid compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. This substance targets the protein interleukin-2.
Experimental
Matched Description: … This substance targets the protein interleukin-2. …
Displaying drugs 3076 - 3100 of 3953 in total