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Displaying drugs 3276 - 3300 of 3846 in total

Aloe ferox leaf

Aloe ferox leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Aloe Ferox Dry Leaf Juice ... Aloe Folium (Aloe Ferox) ... Aloe Folii Extractus (Aloe Ferox) …

Trabedersen

Investigational
Matched Synonyms: … DNA, D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

MAX-40279

MAX-40279 is under investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML)).
Investigational
Matched Synonyms: … 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin- …
Matched Iupac: … N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4- …

OriCar-017

Investigational
Matched Synonyms: … chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D …

Lirentelimab

Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Clofarabine

Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine ... 2-chloro-9-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine …
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …

Diclofenamide

A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Synonyms: … 4,5-dichloro-benzene-1,3-disulfonic acid diamide …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Cefazolin

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. ... A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Categories: … Thiazines …

METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE

Experimental
Matched Name: … METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE …

Nerinetide

Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … -GLUTAMYL-L-SERYL-L-.ALPHA.-ASPARTYL- ... -GLUTAMYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-VALINE ... L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L-.ALPHA …
Matched Categories: … Amino Acids, Peptides, and Proteins …

METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE

Experimental
Matched Name: … METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE …

Dienogest

Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one …
Matched Description: … It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... Dienogest is commonly marketed as Visanne, Natazia and Qlaira. ... in combination with ethinylestradiol, or in other combination form pills approved in United States and …
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... dienogest and estrogen ... dienogest and estradiol ... dienogest and ethinylestradiol …
Matched Products: … DIENOGEST E ETINILESTRADIOLO DOC …

N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE

Experimental
Matched Name: … N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …

Methylphenobarbital

A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …

Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Description: … influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and …
Matched Mixtures name: … DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET ... DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Beta blocking agents and calcium channel blockers ... Calcium-Regulating Hormones and Agents ... ramipril and felodipine ... metoprolol and felodipine …

OXI-4503

OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). In addition, however, preclinical data demonstrates...
Investigational
Matched Name: … OXI-4503 …
Matched Iupac: … [3-methoxy-2-(phosphonooxy)-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to …
Matched Salts name: … OXI-4503 dipotassium …
Matched Categories: … Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids …

Brivoligide

Brivoligide is under investigation in clinical trial NCT04104919 (Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores).
Investigational
Matched Synonyms: … Dna, d(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g ... D(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g …

Sucralfate

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Synonyms: … Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis …
Matched Description: … , bile salts, alcohol, and acetylsalicylic acid (aspirin), among other substances [A177655, F4519]. ... agent_, protecting cells in the gastrointestinal tract from damage caused by agents such as gastric acid ... Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Dom-sucralfate ... DIP SUSPENSION ... DIP 1G/5ML SUSPENSION …

3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)

Investigational
Matched Synonyms: … 3-(4-(8-fluoroquinoline)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …

2-Fluoroadenosine

Experimental
Matched Synonyms: … 6-amino-2-fluoro-9-β-D-ribofuranosylpurine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Monarsen

Investigational
Matched Synonyms: … Dna, d(c-t-g-c-g-a-t-a-t-t-t-t-c-t-t-g-t-ram-rcm-rcm) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

2-(3,4-Dihydro-3-Oxo-2h-Benzo[B][1,4]Thiazin-2-Yl)-N-Hydroxyacetamide

Experimental
Matched Name: … 2-(3,4-Dihydro-3-Oxo-2h-Benzo[B][1,4]Thiazin-2-Yl)-N-Hydroxyacetamide …

Decitabine

Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … DAC ... 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one …
Matched Description: … integrate into cellular DNA and inhibit the action of DNA methyltransferases, leading to global hypomethylation ... presentation, including neutropenia and thrombocytopenia. ... syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …

4-Methoxyamphetamine

Experimental
Illicit
Matched Synonyms: … D,L-p-methoxyamphetamine …
Matched Categories: … Adrenergic alpha-Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Adrenergic alpha-1 Receptor Agonists …

Aracytidine 5'-monophosphate

Experimental
Matched Synonyms: … 1-beta-D-Arabinofuranosylcytosine 5'-phosphate …
Matched Iupac: … 2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Displaying drugs 3276 - 3300 of 3846 in total