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Displaying drugs 3276 - 3300 of 3982 in total
(S)-camphor, or L(-)-Camphor, is a stereoisomer of DB01744, a bicyclic monoterpene known to potentiate both heat and cold sensations . (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and current inhibition . DB01744 is isolated from the wood of the camphor laurel tree, Cinnamomum camphora, and...
Experimental
TBX-1400 consists of human donor hematopoietic stem and progenitor cells.
Investigational
Matched Description: … TBX-1400 consists of human donor hematopoietic stem and progenitor cells. …
Investigational
VB2-011 is an antibody developed as an anti-cancer treatment. According to some preclinical studies, it has a potential to inhibit tumour growth in various cancers including lymphoma and melanoma. This drug includes the parent IgM (H11 IgM) and a recombinant IgG version (H11 IgG).
Investigational
Matched Description: … This drug includes the parent IgM (H11 IgM) and a recombinant IgG version (H11 IgG). …
HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies. It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial.
Investigational
Matched Description: … It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial. ... HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced …
SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer modified alginate spheres
Investigational
Matched Description: … SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral ... vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer modified …
Investigational
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. Merck has...
Investigational
Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Investigational
Vet approved
Matched Products: … EM-MICOFEED 10% Granules ... Sahara Tilmicosin 10% w/w Powder …
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
Rheinanthrone is the active metabolite of senna glycoside DB11365 known for its laxative effect . It is commonly produced by plants of the Rheum species .
Experimental
Matched Iupac: … 4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid …
Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
Matched Description: … After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human
INH-A21 is a human staphylococcal immunoglobulin
Investigational
Matched Description: … INH-A21 is a human staphylococcal immunoglobulin …
GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline (GSK). GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of...
Investigational
Matched Description: … and is currently in Phase I human clinical trials being conducted by GSK. ... GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown ... GSK-923295 is the first drug candidate to enter human clinical trials that specifically targets CENP-E …
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Following four clinical trials, the drug proved to be effective in treating COPD, however it...
Investigational
BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.
Investigational
Matched Description: … BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b. …
Investigational
Investigational
LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9.
Investigational
Matched Description: … LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9. …
HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A
Investigational
Matched Description: … HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A …
Displaying drugs 3276 - 3300 of 3982 in total