Displaying drugs 3376 - 3400 of 3985 in total
Efzofitimod
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
AICA ribonucleotide
5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has been used clinically to treat and protect against cardiac ischemic injury. The drug was first used in the 1980s as...
Experimental
Investigational
Matched Synonyms: … 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide …
Matched Iupac: … [(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Description: … -4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and ... AICAR has been used clinically to treat and protect against cardiac ischemic injury. ... The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … [(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Description: … -4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and ... AICAR has been used clinically to treat and protect against cardiac ischemic injury. ... The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Palomid 529
Palomid 529 has been used in trials studying the treatment of Age-Related Macular Degeneration.
Investigational
Matched Synonyms: … 6H-DIBENZO(B,D)PYRAN-6-ONE, 8-(1-HYDROXYETHYL)-2-METHOXY-3-((4-METHOXYPHENYL)METHOXY)- …
IMT504
IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.
Investigational
Matched Synonyms: … DNA, D(P-THIO)(T-C-A-T-C-A-T-T-T-T-G-T-C-A-T-T-T-T-G-T-C-A-T-T) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid
Experimental
Matched Name: … 3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid …
5-Hydroxyamino-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Experimental
Matched Name: … 5-Hydroxyamino-3-Methyl-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5R)-5-(hydroxyamino)-3-methylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R,3R,5R)-5-(hydroxyamino)-3-methylpyrrolidine-2-carboxylic acid …
2-Amino-3-Oxo-4-Sulfo-Butyric Acid
Experimental
Matched Name: … 2-Amino-3-Oxo-4-Sulfo-Butyric Acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(sulfooxy)propanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(sulfooxy)propanoic acid …
3-(4-Benzenesulfonyl-Thiophene-2-Sulfonylamino)-Phenylboronic Acid
Experimental
Matched Name: … 3-(4-Benzenesulfonyl-Thiophene-2-Sulfonylamino)-Phenylboronic Acid …
Matched Iupac: … {3-[4-(benzenesulfonyl)thiophene-2-sulfonamido]phenyl}boronic acid …
Matched Iupac: … {3-[4-(benzenesulfonyl)thiophene-2-sulfonamido]phenyl}boronic acid …
2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Experimental
Matched Name: … 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(phosphonooxy)propanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(phosphonooxy)propanoic acid …
11-TRANS-13-TRANS-15-CIS-OCTADECATRIENOIC ACID
Experimental
Matched Name: … 11-TRANS-13-TRANS-15-CIS-OCTADECATRIENOIC ACID …
Matched Iupac: … (11E,13E,15Z)-octadeca-11,13,15-trienoic acid …
Matched Iupac: … (11E,13E,15Z)-octadeca-11,13,15-trienoic acid …
(2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Matched Name: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid …
N-[1H-INDOL-3-YL-ACETYL]VALINE ACID
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]VALINE ACID …
Matched Iupac: … (2S)-2-[2-(1H-indol-3-yl)acetamido]-3-methylbutanoic acid …
Matched Iupac: … (2S)-2-[2-(1H-indol-3-yl)acetamido]-3-methylbutanoic acid …
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Experimental
Matched Name: … METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER …
Matched Iupac: … methyl(4-nitrophenoxy)phosphinic acid …
Matched Iupac: … methyl(4-nitrophenoxy)phosphinic acid …
2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID
Experimental
Matched Name: … 2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID …
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid …
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid …
Dexketoprofen
Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched International brands: … KETRON D …
Matched Iupac: … (2S)-2-(3-benzoylphenyl)propanoic acid …
Matched Description: … It is available in the various countries in Europe, Asia and Latin America. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... tramadol and dexketoprofen …
Matched Products: … DKP ... DKP 25 ... DEX-FORTE 50 MG FILM KAPLI TABLET, 20 ADET …
Matched Iupac: … (2S)-2-(3-benzoylphenyl)propanoic acid …
Matched Description: … It is available in the various countries in Europe, Asia and Latin America. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... tramadol and dexketoprofen …
Matched Products: … DKP ... DKP 25 ... DEX-FORTE 50 MG FILM KAPLI TABLET, 20 ADET …
Efocipegtrutide
Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)-L-PROLINE), 1-ETHER WITH .ALPHA …
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Synonyms: … trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid …
Matched Iupac: … sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid …
Matched Description: … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Blood and Blood Forming Organs …
Matched Iupac: … sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid …
Matched Description: … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Blood and Blood Forming Organs …
TH-9402 free base
Investigational
Matched Synonyms: … Benzoic acid, 2-(6-amino-4,5-dibromo-3-imino-3h-xanthen-9-yl)-, methyl ester …
Allisartan isoproxil
Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).
Investigational
Matched Synonyms: … 1H-IMIDAZOLE-5-CARBOXYLIC ACID, 2-BUTYL-4-CHLORO-1-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL …
Olezarsen
Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3).
Investigational
Matched Synonyms: … DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O- ... -D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)- …
(3Z,5S,6R,7S,8R,8aS)-3-(octylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol
Experimental
Matched Name: … (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol …
Matched Iupac: … (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)-hexahydro-1H-[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol …
Matched Iupac: … (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)-hexahydro-1H-[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol …
Ziltivekimab
Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).
Investigational
Matched Synonyms: … Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Elvitegravir
Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the...
Approved
Matched Synonyms: … fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … into the host genome and thereby blocks the formation of the HIV-1 provirus and resulting propagation ... Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. ... elvitegravir must be used in combination with an HIV protease inhibitor coadministered with ritonavir and …
Matched Categories: … emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat …
Matched Iupac: … fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … into the host genome and thereby blocks the formation of the HIV-1 provirus and resulting propagation ... Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. ... elvitegravir must be used in combination with an HIV protease inhibitor coadministered with ritonavir and …
Matched Categories: … emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat …
Displaying drugs 3376 - 3400 of 3985 in total