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Displaying drugs 3376 - 3400 of 3952 in total
Experimental
Matched Name: … 7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Synonyms: … D-Mannitol ... D-(-)-Mannitol …
Matched Description: … or sugar alcohol, in fruits and vegetables. ... Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Cough and Cold Preparations ... Diet, Food, and Nutrition …
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … DL-prenylamine ... N-(3,3-Diphenylpropyl)-alpha-methylphenaethylamin ... N-(3,3-Diphenylpropyl)-alpha-methylphenethylamine …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Carboxylic Acids ... Hydroxy Acids
Experimental
Matched Synonyms: … 5H-Pyrrolo[3,2-d]pyrimidin-4-amine …
Matched Name: … 5H-pyrrolo[3,2-d]pyrimidin-4-amine …
Matched Iupac: … 5H-pyrrolo[3,2-d]pyrimidin-4-amine …
Experimental
Matched Synonyms: … 2-acetamido-2-deoxy-6-O-phosphono-D-glucopyranose …
Matched Name: … N-acetyl-D-glucosamine-6-phosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid
Experimental
Matched Synonyms: … 3-Chlorobenzo(d)isothiazole 1,1-dioxide …
Experimental
Matched Synonyms: … 3-Bromo-d-camphor …
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … [A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or ... Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Dom-brimonidine ... Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis ... TARTRATO DE BRIMONIDINA0.2 % …
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Synonyms: … 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine …
Matched Description: … Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging ... It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. ... in the treatment of nausea and vomiting during pregnancy. …
Matched Salts name: … Buclizine hydrochloride
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the ... Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias. …
Matched Salts name: … Thioridazine hydrochloride
Matched Categories: … Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Thioridazine Hydrochloride
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Human anti-transforming growth factor beta 1 monoclonal antibody ... Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4- …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta
4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Experimental
Matched Synonyms: … 4-amino-5-cyano-7-(D-ribofuranosyl)-7H-pyrrolo(2,3-d)pyrimidine …
Matched Iupac: … 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile …
Matched Description: … It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool ... 4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside …
Experimental
Matched Name: … Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate …
Matched Iupac: … -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)(hydroxy)phosphoryl]oxy}phosphonic acid
Experimental
Matched Synonyms: … 6-Deoxy-2-O-methyl-beta-L-galactopyranose …
Matched Name: … 2-O-Methyl-beta-L-fucopyranose …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Epoetin beta ... Epoetina beta ... Epoetin beta rDNA …
Matched Description: … The product contains the identical amino acid sequence of isolated natural erythropoietin and has the ... recombinant DNA technology and is used for the treatment of patients with anemia associated with various ... beta formulations. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Biopoin ... BIOPOIN 5000 IE /0.5ML SD ... BIOPOIN 1000 I E /0.5ML SD …
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine …
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nortriptyline Hydrochloride ... Dom-nortriptyline 10mg Capsules ... Dom-nortriptyline 25mg Capsules …
Experimental
Matched Name: … (2R,3R,4R,5R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-oxo-3-piperidinyl beta-D-glucopyranoside …
Experimental
Matched Name: … Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BOSENTAN BETA 125MG ... BOSENTAN BETA 62.5MG ... TRACLEER ® 62.5 MG TABLETAS RECUBIERTAS DE PELICULA. …
Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Synonyms: … 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one ... 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide ... 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide …
Matched Iupac: … 3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide …
Matched Description: … guanine bases leading to DNA lesions and eventual apoptosis. ... [A229848, A229858, L32033] Temozolomide is an imidazotetrazine prodrug that is stable at acidic pH but ... Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Betula lenta pollen is the pollen of the Betula lenta plant. Betula lenta pollen is mainly used in allergenic testing.
Approved
Matched Name: … Betula lenta pollen …
Matched Description: … Betula lenta pollen is the pollen of the Betula lenta plant. ... Betula lenta pollen is mainly used in allergenic testing. …
Matched Products: … Betula Lenta Pollen ... Center-AL - Betula Lenta Pollen …
Investigational
Matched Synonyms: … 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-C]pyridine-3,6(2H,5H)-dione …
Matched Iupac: … 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H,2H,3H,5H,6H-pyrazolo[4,3-c]pyridine-3,6-dione …
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and ... does not affect monoamine oxidase activity. …
Matched Salts name: … Maprotiline hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride
An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]
Experimental
Matched Synonyms: … alpha-ketopropionaldehyde …
Matched Description: … An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning ... cell preparations, in various culture media, and in vivo in certain animals. ... It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated …
Displaying drugs 3376 - 3400 of 3952 in total