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Displaying drugs 3401 - 3425 of 3743 in total
Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.
Investigational
Matched Synonyms: … , N-[(3S,4S)-3-[[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d] ... N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin …
Matched Iupac: … N-[(3S,4S)-3-{[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methylazetidin-1-yl)pyrido[3,4-d]pyrimidin …
Experimental
Matched Name: … 2-amino-3-[4-hydroxy-6-oxo-3-(2-phenyl-cyclopropylimino)-cyclohexa-1,4-dienyl]-propionic acid
Matched Iupac: … 2-amino-3-[(5E)-4-hydroxy-2-oxo-5-[(2-phenylcyclopropyl)imino]cyclohex-3-en-1-yl]propanoic acid
Experimental
Matched Name: … Phosporic Acid Mono-[3,4-Dihydroxy-5-(5-Methoxy-Benzoimidazol-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester …
Matched Iupac: … {[(2R,3S,4R,5S)-3,4-dihydroxy-5-(5-methoxy-1H-1,3-benzodiazol-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Name: … 5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE …
Experimental
Matched Name: … 3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID
Matched Iupac: … 3-cyclohexyl-1-[2-(morpholin-4-yl)-2-oxoethyl]-2-phenyl-1H-indole-6-carboxylic acid
Experimental
Matched Name: … [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID
Matched Iupac: … 6R,7R)-4-(4-acetamidophenyl)-3,5-dioxo-4-azatricyclo[5.2.2.0^{2,6}]undecan-1-yl]carbamoyl}oxy)acetic acid
Experimental
Matched Name: … 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID
Matched Iupac: … 2-{[3,5-difluoro-3'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl]carbamoyl}cyclopent-1-ene-1-carboxylic acid
Experimental
Matched Name: … (1S,4R,7AR)-4-BUTOXY-1-[(1R)-1-FORMYLPROPYL]-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID
Matched Iupac: … (1S,4R,7aR)-4-butoxy-1-[(2R)-1-oxobutan-2-yl]-2,4,5,6,7,7a-hexahydro-1H-isoindole-3-carboxylic acid
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Synonyms: … 2-[[2-(Dimethylamino)ethyl]-2-thenylamino]pyridine
Matched Description: … Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. …
Matched Salts name: … Methapyrilene hydrochloride
Matched Categories: … Hypnotics and Sedatives …
Investigational
Matched Synonyms: … 20-hydroxy-.alpha.-ecdysone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … Enzacamene D-L form ... 3-(p-Methylbenzylidene)-DL-camphor …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and
Matched Mixtures name: … mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS ... Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen …
Experimental
Matched Synonyms: … dibutyryl cyclic 3',5'-adenylic acid
Matched Iupac: … (4aR,6R,7R,7aR)-6-(6-butanamido-9H-purin-9-yl)-2-hydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate...
Approved
Investigational
Matched Synonyms: … -(8-chloronaphthalen-1-yl)-2-(((2s)-1- methylpyrrolidin-2-yl)methoxy)-5,6,7,8- tetrahydropyrido(3,4-d) ... (7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2s)-1-methyl-2-pyrrolidinyl)methoxy)pyrido(3,4-d) …
Matched Iupac: … 2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4-d] …
Matched Description: … KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations ... for guanosine triphosphate (GTP) and guanosine diphosphate (GDP), as well as the lack of a clear binding ... Adagrasib targets KRASG12C, one of the most common KRAS mutations, at the cysteine 12 residue and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Experimental
Matched Name: … D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-3,4-dihydroxy-5-(phosphonomethyl)oxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Name: … D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide …
Experimental
Matched Name: … 2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL …
Matched Iupac: … 2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}amino)ethan-1-ol …
Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …
Matched Iupac: … 2-{[(2R,3S,4R)-2,3,4-trihydroxy-5-(phosphonooxy)pentyl]amino}benzoic acid
Experimental
Matched Synonyms: … (S)-2-amino-6-(trimethylammonio)hexanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2 …
Experimental
Matched Name: … Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester …
Experimental
Matched Name: … 2,4-Dinitrophenyl 2-Deoxy-2-Fluoro-Beta-D-Allopyranoside …
Experimental
Matched Name: … 3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide …
Experimental
Matched Name: … 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine …
Matched Iupac: … 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine …
Experimental
Matched Name: … 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE …
Matched Iupac: … 6-(2,6-dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine …
Displaying drugs 3401 - 3425 of 3743 in total