Displaying drugs 3476 - 3500 of 10056 in total
3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol
Experimental
Matched Name: … 3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol …
Matched Iupac: … 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-4,7-dihydro-1H-indole-4,7-dione …
Matched Iupac: … 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-4,7-dihydro-1H-indole-4,7-dione …
Anvatabart opadotin
Investigational
Matched Synonyms: … kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody; conjugated ... (pAF) (121), K120 (217) (121- 218), hinge 1-15 (219 ... gamma1 heavy chain humanized (1-449) [VH humanized (Homo sapiens IGHV3-66*01 (81.6%) -(IGHD) -IGHJ4*01 …
(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE
Experimental
Matched Name: … (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE …
Matched Iupac: … (3E)-4-(1-methyl-1H-indol-3-yl)but-3-en-2-one …
Matched Iupac: … (3E)-4-(1-methyl-1H-indol-3-yl)but-3-en-2-one …
(2s,3r)-1-Amino-2-Methylbutane-2,3-Diol
Experimental
Matched Name: … (2s,3r)-1-Amino-2-Methylbutane-2,3-Diol …
Matched Iupac: … (2S,3R)-1-amino-2-methylbutane-2,3-diol …
Matched Iupac: … (2S,3R)-1-amino-2-methylbutane-2,3-diol …
Dithioerythritol
A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl groups. [PubChem]
Experimental
Ceclazepide
Investigational
Matched Synonyms: … (r)-1-(1-(4-acetoxy-3,3-dimethyl-2-oxo-butyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1h-benzo(e)(1,4)diazepin ... Urea, n-((3r)-1-(4-(acetyloxy)-3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1h-1,4-benzodiazepin ... -3-yl)-3-(3-methylamino-phenyl)-urea …
Matched Iupac: … -1,4-benzodiazepin-1-yl]-3-oxobutyl acetate ... 2,2-dimethyl-4-[(3R)-3-({[3-(methylamino)phenyl]carbamoyl}amino)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H …
Matched Iupac: … -1,4-benzodiazepin-1-yl]-3-oxobutyl acetate ... 2,2-dimethyl-4-[(3R)-3-({[3-(methylamino)phenyl]carbamoyl}amino)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H …
gp209-2M antigen
The gp209-2M antigen is derived from gp209, and has potential immunomodulatory and antineoplastic activities.
Investigational
3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Experimental
Matched Name: … 3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione …
Matched Iupac: … 3-(1H-indol-3-yl)-4-(1-{2-[(2R)-1-methylpyrrolidin-2-yl]ethyl}-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole- …
Matched Iupac: … 3-(1H-indol-3-yl)-4-(1-{2-[(2R)-1-methylpyrrolidin-2-yl]ethyl}-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole- …
(2Z)-1-(5-Chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-tetrazol-5-yl)-2-propen-1-one
Experimental
Matched Synonyms: … 1-(5-Chloroindol-3-YL)-3-hydroxy-3-(2H-tetrazol-5-YL)-propenone …
Matched Name: … (2Z)-1-(5-Chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-tetrazol-5-yl)-2-propen-1-one …
Matched Iupac: … (2Z)-1-(5-chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-1,2,3,4-tetrazol-5-yl)prop-2-en-1-one …
Matched Name: … (2Z)-1-(5-Chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-tetrazol-5-yl)-2-propen-1-one …
Matched Iupac: … (2Z)-1-(5-chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-1,2,3,4-tetrazol-5-yl)prop-2-en-1-one …
Dabocemagene autoficel
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … WITH A NON-REPLICATING, SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND 3' …
3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one
Experimental
Matched Name: … 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one …
Matched Iupac: … 3-{[(3S)-3,4-dihydroxybutoxy]amino}-1H,2'H-[2,3'-biindol]-2'-one …
Matched Iupac: … 3-{[(3S)-3,4-dihydroxybutoxy]amino}-1H,2'H-[2,3'-biindol]-2'-one …
Treprostinil palmitil
Investigational
Matched Synonyms: … Acetic acid, 2-(((1r,2r,3as,9as)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3s)- 3-hydroxyoctyl)-1h-benz(f ... Hexadecyl 2-(((1r,2r,3as,9as)-2-hydroxy-1-((s)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1h-cyclopenta( …
Seclidemstat
Investigational
Matched Synonyms: … Benzoic acid, 3-((4-methyl-1-piperazinyl)sulfonyl)-, (2e)-2-(1-(5-chloro-2-hydroxyphenyl)ethylidene)hydrazide ... N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]- 3-(4-methylpiperazine-1-sulfonyl)benzohydrazide …
Matched Iupac: … N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]-3-[(4-methylpiperazin-1-yl)sulfonyl]benzohydrazide …
Matched Iupac: … N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]-3-[(4-methylpiperazin-1-yl)sulfonyl]benzohydrazide …
(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
Experimental
Matched Name: … (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
(R)-Gossypol
(R)-Gossypol is the R-isomer of Gossypol.
Investigational
Matched Synonyms: … (r)-2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) …
Matched Iupac: … 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(propan-2-yl)-[2,2'-binaphthalene]-8,8'-dicarbaldehyde …
Matched Iupac: … 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(propan-2-yl)-[2,2'-binaphthalene]-8,8'-dicarbaldehyde …
Icapamespib
Investigational
Matched Iupac: … 9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine …
Matched Salts cas: … 2267287-26-1 …
Matched Salts cas: … 2267287-26-1 …
N-[(1S)-1-{1-[(1R,3E)-1-ACETYLPENT-3-EN-1-YL]-1H-1,2,3-TRIAZOL-4-YL}-1,2-DIMETHYLPROPYL]BENZAMIDE
Experimental
Matched Name: … N-[(1S)-1-{1-[(1R,3E)-1-ACETYLPENT-3-EN-1-YL]-1H-1,2,3-TRIAZOL-4-YL}-1,2-DIMETHYLPROPYL]BENZAMIDE …
Matched Iupac: … N-[(2S)-3-methyl-2-{1-[(3R,5E)-2-oxohept-5-en-3-yl]-1H-1,2,3-triazol-4-yl}butan-2-yl]benzamide …
Matched Iupac: … N-[(2S)-3-methyl-2-{1-[(3R,5E)-2-oxohept-5-en-3-yl]-1H-1,2,3-triazol-4-yl}butan-2-yl]benzamide …
GC-376 free acid
GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov...
Experimental
Matched Iupac: … (2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane ... -1-sulfonic acid …
Matched Description: … A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Encaleret
Investigational
Matched Synonyms: … 2'-((1r)-1-((2r)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3 ... 2'-((1r)-1-(((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-(2r)-2-hydroxypropoxy)ethyl)-3-methyl ... 2'-((1r)-1-(((2r)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl …
Matched Iupac: … 2'-[(1R)-1-[(2R)-3-{[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3 …
Matched Salts cas: … 1214922-52-7 …
Matched Iupac: … 2'-[(1R)-1-[(2R)-3-{[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3 …
Matched Salts cas: … 1214922-52-7 …
Rezatapopt
Rezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).
Investigational
Matched Synonyms: … -2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methyl- ... 4-[[3-[4-[[(3S,4R)-3-Fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn ... Benzamide, 4-[[3-[4-[[(3S,4R)-3-fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol …
(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
Experimental
Matched Name: … -yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol ... (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … -yl]cyclopentyl]prop-2-en-1-ylidene]cyclohexane-1,3-diol ... (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … -yl]cyclopentyl]prop-2-en-1-ylidene]cyclohexane-1,3-diol ... (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Indirubin-3'-monoxime
Experimental
Matched Synonyms: … 1H,1'H-[2,3']biindolylidene3,2'-dione-3-oxime …
Matched Name: … Indirubin-3'-monoxime …
Matched Iupac: … (Z,3E)-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … Indirubin-3'-monoxime …
Matched Iupac: … (Z,3E)-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL
Experimental
Matched Name: … 1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-{4-[(2,2,2-trifluoroethyl)amino]phenyl}propan-2-ol …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-{4-[(2,2,2-trifluoroethyl)amino]phenyl}propan-2-ol …
Displaying drugs 3476 - 3500 of 10056 in total