Displaying drugs 3601 - 3625 of 3938 in total
Filgrastim
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous ... [L40719] It has a number of therapeutic uses, including the management and prevention of infections and ... G-CSF and has an N-terminal methionine added in the sequence for expression in _E. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML ... ACCOFIL 48 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 48 MU/0.5 ML …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML ... ACCOFIL 48 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 48 MU/0.5 ML …
Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate
Experimental
Matched Synonyms: … Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome …
Matched Name: … )phosphoryl}-L-alanyl-L-prolinate ... Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy …
Matched Iupac: … ]({[(2S)-1-[(2S)-2-(methoxycarbonyl)pyrrolidin-1-yl]-1-oxopropan-2-yl]amino})phosphinic acid ... [(1R)-1-[(2S)-6-azaniumyl-2-{[(2S)-1-[(benzyloxy)carbonyl]pyrrolidin-2-yl]formamido}hexanamido]-2-phenylethyl …
Matched Name: … )phosphoryl}-L-alanyl-L-prolinate ... Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy …
Matched Iupac: … ]({[(2S)-1-[(2S)-2-(methoxycarbonyl)pyrrolidin-1-yl]-1-oxopropan-2-yl]amino})phosphinic acid ... [(1R)-1-[(2S)-6-azaniumyl-2-{[(2S)-1-[(benzyloxy)carbonyl]pyrrolidin-2-yl]formamido}hexanamido]-2-phenylethyl …
{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid
Experimental
Matched Name: … (1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid …
Matched Iupac: … -carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl]carbamoyl}-2-acetamidoethyl]-2-phosphonophenoxy}acetic acid …
Matched Iupac: … -carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl]carbamoyl}-2-acetamidoethyl]-2-phosphonophenoxy}acetic acid …
(1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid
Experimental
Matched Name: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid …
Matched Iupac: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid …
Matched Iupac: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid …
3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid
Experimental
Matched Name: … 1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid …
Matched Iupac: … 1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid …
Matched Iupac: … 1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid …
4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID
Experimental
Matched Name: … 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID …
Matched Iupac: … 4-{[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}benzoic acid …
Matched Iupac: … 4-{[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}benzoic acid …
2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID
Experimental
Matched Name: … 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID …
Matched Iupac: … {[5-(pyridin-2-ylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}amino)methyl]-1H-imidazol-4-yl}phenoxy)acetic acid …
Matched Iupac: … {[5-(pyridin-2-ylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}amino)methyl]-1H-imidazol-4-yl}phenoxy)acetic acid …
Leukotriene C4
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and...
Experimental
Investigational
Matched Synonyms: … (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl ... L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycine …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … SRS-A ... Arachidonic Acids ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … SRS-A ... Arachidonic Acids ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor necrosis factor .alpha …
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
Duloxetine
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. ... Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. ... pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence. …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … N/A ... Ag-duloxetine ... Apo-duloxetine …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … N/A ... Ag-duloxetine ... Apo-duloxetine …
[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester
Experimental
Matched Name: … Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid …
2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid
Experimental
Matched Name: … 2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid …
Matched Iupac: … -[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-4-{4'-ethoxy-[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
Matched Iupac: … -[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-4-{4'-ethoxy-[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE
Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL] …
(7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid
Experimental
Matched Name: … Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
(2S)-({(5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid
Experimental
Matched Name: … (5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid …
Matched Iupac: … [(5-ethylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}-2-(4-fluorophenyl)acetic acid …
Matched Iupac: … [(5-ethylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}-2-(4-fluorophenyl)acetic acid …
ORC-13661
ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin).
Investigational
Matched Synonyms: … (4R,6S)-2-[[[(4-Chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5-methyl-4,6-ethanothieno[3,2-c ... 4,6-Ethanothieno[3,2-c]pyridine-3-carboxamide, 2-[[[(4-chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro …
Elinzanetant
Elinzanetant is under investigation in clinical trial NCT05099159 (A Study to Learn More About How Well Elinzanetant Works and How Safe It Is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause (OASIS-2)).
Investigational
Matched Synonyms: … .,.alpha. ... methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,.alpha …
Matched Description: … Elinzanetant Works and How Safe It Is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are ... Elinzanetant is under investigation in clinical trial NCT05099159 (A Study to Learn More About How Well …
Matched Description: … Elinzanetant Works and How Safe It Is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are ... Elinzanetant is under investigation in clinical trial NCT05099159 (A Study to Learn More About How Well …
Vincristine
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Description: … liposomal injection) and Vincasar. ... significant bone–marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy ... indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. …
Nemvaleukin alfa
Investigational
Matched Synonyms: … of IL-2 receptor alpha ... Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain ... human) fusion protein with peptide linker (gsgggs) fusion protein with 1-165-interleukin 2 receptor .alpha …
N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide
Experimental
Matched Synonyms: … N-[(benzyloxy)carbonyl]leucyl-N(1)-[3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]leucinamide …
Matched Name: … N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide …
Matched Name: … N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide …
Ziritaxestat
Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis).
Investigational
Matched Synonyms: … 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin …
Matched Iupac: … 2-[(2-ethyl-6-{4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl}-8-methylimidazo[1,2-a]pyridin …
Matched Description: … and Safe GLPG1690 is for Patients With Systemic Sclerosis). ... Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective …
Matched Iupac: … 2-[(2-ethyl-6-{4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl}-8-methylimidazo[1,2-a]pyridin …
Matched Description: … and Safe GLPG1690 is for Patients With Systemic Sclerosis). ... Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective …
Firolimogene autotemcel
Investigational
Matched Synonyms: … NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY (X-SCID) PATIENTS, TRANSDUCED EX VIVO WITH A …
Uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-galactose
Experimental
Matched Name: … Uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-galactose …
Matched Iupac: … )oxy]phosphinic acid ... dihydroxyoxolan-2-yl]methoxy}[({[(2R,3R,4S,5S,6R)-3-fluoro-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}(hydroxy)phosphoryl …
Matched Iupac: … )oxy]phosphinic acid ... dihydroxyoxolan-2-yl]methoxy}[({[(2R,3R,4S,5S,6R)-3-fluoro-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}(hydroxy)phosphoryl …
Displaying drugs 3601 - 3625 of 3938 in total