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Displaying drugs 3601 - 3625 of 4302 in total
Experimental
Matched Name: … 4,6-dideoxy-4-amino-alpha-D-glucose …
Experimental
Matched Name: … N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide …
Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational
Matched Synonyms: … XCEL-UMC-BETA
Matched Description: … The umbilical cord, which starts developing in the fifth week of gestation, contains different compartments ... their own version of these stem cells, one of which is by Aspire, who are creating a version named ACT-20 ... Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity …
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Description: … investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and
Matched Salts cas: … 1849590-02-8
Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one …
Matched Iupac: … 6-amino-9-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-7-(4-phenoxyphenyl)-8,9-dihydro-7H-purin-8-one …
Matched Description: … 4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)). ... Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- …
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Description: … It is available as a tablet and is usually dosed twice daily. ... antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and ... on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Accolate Tab 20 mg ... CARROX 20 MG FILM TABLET, 28 TABLET ... ACCOLATE 20 MG TABLETA RECUBIERTA. …
Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Approved
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-8-oxo-3-(prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0 …
Matched Description: … skin, bronchitis, and others. ... antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and
Matched Categories: … beta-Lactams ... beta Lactam Antibiotics …
Matched Products: … CEFNOR 250 MG EFERVESAN TABLET, 20 ADET ... PREFIX 250 MG FILM TABLET, 20 ADET ... CEFNOR 500 MG EFERVESAN TABLET, 20 ADET …
Experimental
Matched Name: … 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake...
Approved
Investigational
Matched Description: … It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action ... an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. ... serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and
Matched Products: … KELAC® 20 MG ... บรินเทลิกซ์ 20 มก. ... BRINTELLIX® 20 MG …
Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
Approved
Withdrawn
Matched Mixtures name: … เชริพร็อค(R) เอ็น ... ULTRALAN POMAT, 20 GR …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... fluocortolone and antibiotics ... fluocortolone and antiseptics ... fluocortolone and antiinfectives …
Matched Products: … ULTRALAN 20 MG TABLET, 500 ADET ... ULTRALAN 20 MG TABLET, 10 ADET ... ULTRALAN ORAL 5 MG TABLET, 20 ADET …
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Synonyms: … Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha
Matched Description: … masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha
Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Description: … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin ... infections such as athlete's foot, jock itch and ringworm. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … OXEZOLE %1 KREM, 20 G ... OXEZOLE %1 DERI SPREYI, ÇÖZELTİ 20 ML ... ZOLEXOL % 1 DERI SPREYI, ÇÖZELTİ, 20 ML …
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MEGAPTH-G Teriparatide 20 micrograms / 80 microliters solution for injection ... FORSTEO 20 MCG/80 MCL KULLANIMA HAZIR DOLU ENJEKSIYON KALEMI ICINDE COZELTI, 2.4 ML ... SONDELBAY (Teriparatide) 20 micrograms/ 80 microliters solution for injection in pre-filled pen …
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and ... metabolite of the pro-drug [carbimazole], which is an antithyroid medication used in the United Kingdom and
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … THYROZOL 20 ... METHIZOL SD 20MG ... THIAMAZOL 20MG HEXAL …
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Description: … acute graft-versus-host disease in adults and children. ... response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in steroid-refractory ... It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Jakavi 20mg Tablets ... JAKAVI TABLET 20MG ... JAKAVI 20 MG (TABLETS) …
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. ... [L764] Adlyxin recieved FDA approval July 28, 2016.[L763] …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA® 20 MCG / 0.2 ML ... LYXUMIA (SOLUTION FOR INJECTION 20 MCG) ... LYXUMIA 20 MCG ENJEKSIYON IÇIN ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM ,1 KALEM …
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... beta-N-Acetylhexosaminidases ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse ... Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. ... Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … Antiglaucoma Preparations and Miotics ... latanoprost and netarsudil ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Products: … PEGEA %0.005 GÖZ DAMLASI, ÇÖZELTİ, 2,5 ML ... OFTIDON® SOLUCION OFTALMICA ESTERIL ... LOUTEN ® EMULSION OFTALMICA ESTERIL
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Description: … Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. ... ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Matched Categories: … beta-Lactamase Inhibitors ... Beta-Lactam Antibacterials ... Extended-spectrum beta-lactamase inhibitors …
Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Iupac: … -1(9),11-dien-8-yl]methyl carbamate ... [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca …
Matched Description: … , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... approval for its use in low-grade Upper Tract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... Indicators and Reagents …
Matched Products: … MITOMICINA 20 ... MUTAMYCIN 20 MG ... Mutamycin Inj 20mg/vial …
Investigational
Matched Synonyms: … SPR-720 FREE ACID
Matched Iupac: … amino]-6-fluoro-7-[(2R)-oxolan-2-yl]-1H-1,3-benzodiazol-5-yl}pyrimidin-2-yl)propan-2-yl]oxy}phosphonic acid
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Recombinant human growth hormone fused to alpha1-antitrypsin variant …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction pathway. It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or...
Approved
Investigational
Matched Description: … protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction ... Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated ... It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … COTELLIC FILM-COATED TABLET 20 MG ... COTELLIC FILM COATED TABLET 20MG ... COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTAS …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Pharma 80 mg-Filmtabletten ... LITEDA 20 MG ... Dasatinib G.L. 80 mg-Filmtabletten …
Investigational
Matched Products: … SOLCOSERYL EYE GEL 20% ... SOLCOSERYL JELLY 2 g/20 g ... SOLCOSERYL OINTMENT 1 g/20 g …
Displaying drugs 3601 - 3625 of 4302 in total