Displaying drugs 3701 - 3725 of 8028 in total
Depelestat
Investigational
Matched Synonyms: … Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
IMT504
IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.
Investigational
Matched Synonyms: … PyNTTTTGT class of oligodeoxynucleotide with a 24-base single chain composed of nucleotide sequence 5 …
STM-217
Investigational
Matched Synonyms: … Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a …
FB-825
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment of …
Matched Description: … IgE (mIgE), causing a depletion of mIgE positive B-cells. ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Matched Description: … IgE (mIgE), causing a depletion of mIgE positive B-cells. ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
AAV2/8.TBG.hARSB
Investigational
Matched Synonyms: … vector serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter driving the expression of …
Lagerstroemia indica whole
Lagerstroemia indica whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Pride of India Whole …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Description: … This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription …
Matched Description: … designed to down-regulate the expression of EVI1 oncogene in cancer cells. ... PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Matched Description: … designed to down-regulate the expression of EVI1 oncogene in cancer cells. ... PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
GTB-3550
GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin 15 (IL-15).
Investigational
Matched Synonyms: … single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 …
Matched Description: … regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin ... GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable …
Matched Description: … regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin ... GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable …
NBL-015
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Volrubigene ralaparvovec
Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated viral vector, serotype 8, expressing the 1A1 isoform of …
Inodiftagene vixteplasmid
Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed non-protein coding gene).
Investigational
Matched Synonyms: … Dna Plasmid Expressing Diphtheria Toxin Triggered By The Presence Of Oncofetal Gene H19 …
Matched Description: … is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of ... the promoter region of the human H19 gene (an imprinted maternally expressed non-protein coding gene …
Matched Description: … is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of ... the promoter region of the human H19 gene (an imprinted maternally expressed non-protein coding gene …
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Matched Synonyms: … an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …
Tomaralimab
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Matched Description: … investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of …
Matched Description: … investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of …
Cirtuvivint
Cirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor.
Investigational
Matched Synonyms: … CDC-like kinase inhibitor of the Wnt Pathway …
Butylidenephthalide
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …
Ergidina
Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …
CYNK-101
CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Investigational
Matched Synonyms: … derived natural killer (NK) cell therapy product that is genetically modified to express a variant of …
Matched Description: … cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of …
Matched Description: … cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of …
Cinnamic acid
Investigational
Matched Synonyms: … Cinnamic acid (constituent of cinnamomum verum bark) ... Trans-cinnamic acid (constituent of cinnamomum cassia bark) …
Eltrapuldencel-T
Investigational
Matched Synonyms: … loaded with antigen from self-renewing, proliferating autologous irradiated tumour cells, in a solution of …
EB003
EB003 is a CRISPR-based sequence-specific antimicrobial (SSAM) targeted against shiga toxin-producing E. coli.
Investigational
Matched Synonyms: … non-replicative delivery vector carrying a DNA payload encoding an RNA-guided nuclease that targets stx genes of …
RP-72
Investigational
Matched Synonyms: … 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin …
AAV9/MFSD8
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for expression of …
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of …
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of …
Displaying drugs 3701 - 3725 of 8028 in total