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Displaying drugs 3776 - 3800 of 9026 in total
PR006
PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene. It is being investigated for the treatment of dementia.
Investigational
PBR-06 F-18
Investigational
Matched Synonyms: … Acetamide, n-((2,5-dimethoxyphenyl)methyl)-2-(fluoro-18f)-n-(2-phenoxyphenyl)- …
Matched Iupac: … N-[(2,5-dimethoxyphenyl)methyl]-2-(¹⁸F)fluoro-N-(2-phenoxyphenyl)acetamide …
Matched Iupac: … N-[(2,5-dimethoxyphenyl)methyl]-2-(¹⁸F)fluoro-N-(2-phenoxyphenyl)acetamide …
NRC-AN-019
Investigational
Matched Synonyms: … 3,5-BIS(TRIFLUOROMETHYL)-N-(4-METHYL-3-((4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)AMINO)PHENYL)BENZAMIDE ... (3,5-BIS TRIFLUOROMETHYL)-N-(4-METHYL-3-(4-PYRIDIN-3YL-PYRIMIDIN-2-YL AMINO) PHENYL)BENZAMIDE ... (3,5-Bis Trifluoromethyl)-N-[4-Methyl-3-(4-Pyridin-3Yl-Pyrimidin-2-Yl Amino) Phenyl] Benzamide …
SNS01-T
SNS01-T is a gene therapy nanoparticle. It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.
Investigational
RR001
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
TTAX01
TTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.
Investigational
ALMB-0166
ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.
Investigational
NX001
Investigational
EB003
EB003 is a CRISPR-based sequence-specific antimicrobial (SSAM) targeted against shiga toxin-producing E. coli.
Investigational
PBGM01
PBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.
Investigational
CT-179
Investigational
Matched Synonyms: … 1-(2-(3-(3,4-dichlorophenyl)ureido)-6-methyl-pyrimidin-4-yl)-amino-3(dimethylamino)propane ... Urea, n-(3,4-dichlorophenyl)-n'-(4-((3-(dimethylamino)propyl)amino)-6-methyl-2-pyrimidinyl)- …
Matched Iupac: … 1-(3,4-dichlorophenyl)-3-(4-{[3-(dimethylamino)propyl]amino}-6-methylpyrimidin-2-yl)urea …
Matched Iupac: … 1-(3,4-dichlorophenyl)-3-(4-{[3-(dimethylamino)propyl]amino}-6-methylpyrimidin-2-yl)urea …
NSI-189
NSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder).
Investigational
Matched Iupac: … 3-(4-benzylpiperazine-1-carbonyl)-N-(3-methylbutyl)pyridin-2-amine …
(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine
Experimental
Matched Name: … 3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine ... (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[( …
Matched Iupac: … (2S,3S)-2-amino-4-cyclopropyl-3-[(3R)-3-(2-fluoro-4-methanesulfonylphenyl)-1,2,4-oxadiazolidin-5-yl]- ... 1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one …
Matched Iupac: … (2S,3S)-2-amino-4-cyclopropyl-3-[(3R)-3-(2-fluoro-4-methanesulfonylphenyl)-1,2,4-oxadiazolidin-5-yl]- ... 1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one …
(2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide
Experimental
Matched Name: … (2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide …
Matched Iupac: … (2S)-N-[(3E)-5-cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxoimidazolidin-1-yl)phenyl]propanamide …
Matched Iupac: … (2S)-N-[(3E)-5-cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxoimidazolidin-1-yl)phenyl]propanamide …
Icaritin
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE
Experimental
Matched Name: … 2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE …
Matched Iupac: … 2-chloro-N-[(3R)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-6H-thieno[2,3-b]pyrrole-5-carboxamide …
Matched Iupac: … 2-chloro-N-[(3R)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-6H-thieno[2,3-b]pyrrole-5-carboxamide …
(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE
Experimental
Matched Name: … (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE …
Matched Iupac: … (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one …
Matched Iupac: … (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one …
alpha-Naphthoflavone
Experimental
Matched Synonyms: … 2-phenyl-4H-naphtho(1,2-b)pyran-4-one …
Matched Iupac: … 2-phenyl-4H-benzo[h]chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-phenyl-4H-benzo[h]chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
B7-H3-specific chimeric antigen receptor T cells
Investigational
Atiprimod
Investigational
Matched Synonyms: … N,N-Diethyl-8,8-dipropyl-2-azaspiro(4.5)decane-2-propanamine …
Matched Iupac: … (3-{8,8-dipropyl-2-azaspiro[4.5]decan-2-yl}propyl)diethylamine …
Matched Iupac: … (3-{8,8-dipropyl-2-azaspiro[4.5]decan-2-yl}propyl)diethylamine …
NCX 701
Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.
Investigational
NOX-700
NOX-700, an new orally active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 diabetes). In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin. Immunohistochemical studies on
pancreatic tissue also showed that...
Investigational
Matched Description: … nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 …
KW-7158
KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the bladder). The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels...
Investigational
Matched Iupac: … ),3(7),5,11,13-pentaen-14-yl}propanamide ... (2S)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-{2,9,9-trioxo-4,9λ⁶-dithiatricyclo[8.4.0.0³,⁷]tetradeca-1(10 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
MIV-701
MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. It is developed for the treatment of osteoporosis.
Investigational
Displaying drugs 3776 - 3800 of 9026 in total