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Displaying drugs 3876 - 3900 of 9053 in total
Navocaftor
Navocaftor is under investigation in clinical trial NCT04853368 (Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/navocaftor/abbv-119 or Galicaftor/navocaftor/abbv-576 Combination Therapies in Adult Participants With Cystic Fibrosis).
Investigational
Matched Synonyms: … (5-(3-amino-5-((4-(trifluoromethoxy)phenyl)sulfonyl)pyridin-2-yl)-1,3,4-oxadiazol-2-yl)methanol ... 1,3,4-oxadiazole-2-methanol, 5-(3-amino-5-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-pyridinyl)- …
6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE
Experimental
Dimethyltryptamine
An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Experimental
Illicit
Tolperisone
Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. Based on existing clinical data, Tolperisone is not...
Investigational
Matched Iupac: … 2-methyl-1-(4-methylphenyl)-3-(piperidin-1-yl)propan-1-one …
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cilofexor
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … -1-yl]pyridine-4-carboxylic acid ... 2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin …
Matched Iupac: … -1-yl]pyridine-4-carboxylic acid ... 2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … -1-yl]pyridine-4-carboxylic acid ... 2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bleximenib
Bleximenib is under investigation in clinical trials NCT04811560 (A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia) and NCT05453903 (A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies)
Investigational
Matched Synonyms: … Benzamide, N-ethyl-5-fluoro-2-[[5-[2-[(1R)-4-[(2-methoxyethyl)methylamino]-1-(1-methylethyl)butyl]-2,6 ... N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[ ... -diazaspiro[3.4]oct-6-yl]-1,2,4-triazin-6-yl]oxy]-N-(1-methylethyl)- …
Matched Description: … Bleximenib is under investigation in clinical trials NCT04811560 (A Phase 1/2 Study of Bleximenib in …
Matched Description: … Bleximenib is under investigation in clinical trials NCT04811560 (A Phase 1/2 Study of Bleximenib in …
5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide
Experimental
Matched Name: … 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide …
Matched Iupac: … 5-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide …
Matched Iupac: … 5-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide …
5-(5-(6-CHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE
Experimental
Matched Name: … 5-(5-(6-CHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE …
Matched Iupac: … 5-{5-[2-chloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl}-3-methyl-1,2-oxazole …
Matched Iupac: … 5-{5-[2-chloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl}-3-methyl-1,2-oxazole …
(1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose
Experimental
Matched Synonyms: … 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE …
Matched Name: … (1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose …
Matched Iupac: … -1-one ... (3R)-7-[(2R)-butan-2-yl]-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-8,9-dihydroxy-1,2,3,4-tetrahydroanthracen …
Matched Name: … (1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose …
Matched Iupac: … -1-one ... (3R)-7-[(2R)-butan-2-yl]-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-8,9-dihydroxy-1,2,3,4-tetrahydroanthracen …
(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one
Experimental
Matched Name: … (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2 …
Matched Iupac: … -1(10),2(7),3,5,8,12(18)-hexaen-13-one ... (15R)-15-methyl-5-(6-methylpyridin-3-yl)-11-thia-6,14,17-triazatetracyclo[8.8.0.0^{2,7}.0^{12,18}]octadeca …
Matched Iupac: … -1(10),2(7),3,5,8,12(18)-hexaen-13-one ... (15R)-15-methyl-5-(6-methylpyridin-3-yl)-11-thia-6,14,17-triazatetracyclo[8.8.0.0^{2,7}.0^{12,18}]octadeca …
AVX-001
AVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult Subjects With AK).
Investigational
Matched Synonyms: … 1-((2e,6z,9z,12z,15z)-octadeca-3,6,9,12,15-pentaen-1-thio)-3,3,3-trifluoroacetone …
Matched Description: … AVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel ... in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult …
Matched Description: … AVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel ... in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult …
Disitertide
Disitertide has been used in trials studying the treatment of Skin Fibrosis.
Investigational
Matched Synonyms: … Peptide 144 TGF beta-1 inhibitor …
5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole
5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. This medication is known to target genome polyprotein.
Experimental
Matched Name: … 5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole …
Matched Iupac: … 3-methyl-5-(5-{4-[(4S)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}pentyl)-1,2-oxazole …
Matched Description: … 5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole is a solid. …
Matched Iupac: … 3-methyl-5-(5-{4-[(4S)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}pentyl)-1,2-oxazole …
Matched Description: … 5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole is a solid. …
Dimethylthiambutene
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Experimental
Illicit
Matched Synonyms: … 3-dimethylamino-1,1-bis(2-thienyl)-1-butene ... 3-dimethylamino-1,1-di-(2'-thienyl)-1-butene ... N,N,1-trimethyl-3,3-di-2-thienylallylamine …
Matched Description: … Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid ... It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs …
Matched Description: … Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid ... It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs …
A-98881
Experimental
Matched Iupac: … (5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,2,4-triazepan-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
3,4-dihydroxy-9,10-secoandrosta-1(10),2,4-triene-9,17-dione
Experimental
Matched Name: … 3,4-dihydroxy-9,10-secoandrosta-1(10),2,4-triene-9,17-dione …
Matched Iupac: … (3aS,4S,7aS)-4-[2-(2,3-dihydroxy-6-methylphenyl)ethyl]-7a-methyl-octahydro-1H-indene-1,5-dione …
Matched Iupac: … (3aS,4S,7aS)-4-[2-(2,3-dihydroxy-6-methylphenyl)ethyl]-7a-methyl-octahydro-1H-indene-1,5-dione …
5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid
Experimental
Matched Name: … 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
Tretamine
Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Experimental
Matched Synonyms: … 2,4,6-tri(1-aziridinyl)-1,3,5-triazine ... 2,4,6-tris(1-aziridinyl)-s-triazine ... 2,4,6-tris(1-aziridinyl)-1,3,5-triazine …
Matched Iupac: … tris(aziridin-1-yl)-1,3,5-triazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … tris(aziridin-1-yl)-1,3,5-triazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Coptisine
Investigational
Matched Synonyms: … 6,7-dihydrobis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium ... Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, 6,7-dihydro- …
Bifidobacterium animalis lactis
Experimental
5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
Investigational
Matched Synonyms: … 5-((trans-4-(4-(trifluoromethoxy)phenyl)cyclohexyl)oxy)-1h-1,2,3-triazole-4-carboxylic acid ... 5-[[trans-4-[(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
CHROMOPHORE (LYS-TYR-GLY)
Experimental
Matched Iupac: … 2-[(4Z)-2-[(1S)-1,5-diaminopentyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl …
PBT-1033
Investigational
Displaying drugs 3876 - 3900 of 9053 in total