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Displaying drugs 376 - 400 of 603 in total
Satralizumab
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody …
Matched Description: … Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL- ... formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL- ... formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Water
Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … rain, and is the major constituent of the fluids of organisms. ... its solid state, ice; and gaseous state, steam (water vapor). ... Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and …
Matched Mixtures name: … Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … Salinaax Eye Wash and Skin Flush ... Aerowash Eyewash and Skin-Rinse ... Xpect First aid Buffered Eye and Skin …
Matched Mixtures name: … Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … Salinaax Eye Wash and Skin Flush ... Aerowash Eyewash and Skin-Rinse ... Xpect First aid Buffered Eye and Skin …
SBT-100
SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Investigational
Matched Synonyms: … Anti-STAT3 B VHH13 single domain antibody …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Synonyms: … Recombinant human IgG monoclonal HPA-1a antibody …
Matched Description: … RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). ... It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia …
Matched Description: … RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). ... It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia …
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Bandha for and Mask …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Bandha for and Mask …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
AOC 1001
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting ... , effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA ( …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Methylcellulose
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Zinc sulfate
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Description: … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Calcium and Magnesium W Zinc Tab ... Prenatal Vitamin and Mineral Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Skin and Mucous Membrane Agents ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Anu-aide - Ont Top 0.5% …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Calcium and Magnesium W Zinc Tab ... Prenatal Vitamin and Mineral Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Skin and Mucous Membrane Agents ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Anu-aide - Ont Top 0.5% …
Fazpilodemab
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 ... Bfkb-8488a (bispecific antibody designed to mimic the metabolic hormone fgf21). ... (fibroblast growth factor receptor 1, FLT2, KAL2)], monoclonal antibody, bispecific; gamma1 heavy chain …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …
Tifcemalimab
Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … Sutimlimab is a first-in-class humanized monoclonal antibody targeted at complement subunit C1s, which ... [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Sutimlimab is a first-in-class humanized monoclonal antibody targeted at complement subunit C1s, which ... [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Benzethonium
Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Mixtures name: … Gold Bond Pain and Itch ... Benzocaine and Benzethonium ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Loesch Original Kleer-Plex Antimicrobial Face and Body Wash …
Matched Mixtures name: … Gold Bond Pain and Itch ... Benzocaine and Benzethonium ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Loesch Original Kleer-Plex Antimicrobial Face and Body Wash …
Lanolin
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... Vitamin A and D ... Vitamins A and D …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... Vitamin A and D ... Vitamins A and D …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Nitroglycerin
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … TOP-NITRO …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … TOP-NITRO …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Emollients Demulcents and Protectants ... Aluminum and magnesium containing antacids …
Matched Products: … Dermagran II Ointment-ont Top 0.25% …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Emollients Demulcents and Protectants ... Aluminum and magnesium containing antacids …
Matched Products: … Dermagran II Ointment-ont Top 0.25% …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Synonyms: … Anti-CD 154 human-mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ordesekimab
Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).
Investigational
Matched Synonyms: … Human IgG1 anti-IL-15 monoclonal antibody …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
NKX101
NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Investigational
Matched Synonyms: … NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and …
AD-214
Investigational
Matched Synonyms: … Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and …
Minoxidil
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …
Rivabazumab pegol
Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … PEGylated recombinant anti-Pseudomonas aeruginosa PcrV Fab' antibody ... KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS ... ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN, PEGYLATED HUMANIZED MONOCLONAL ANTIBODY …
Famotidine
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … gastroesophageal reflux disease (GERD), in adults and children. ... [A189462] Famotidine is used in various over-the-counter and off-label uses. ... It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and …
Matched Mixtures name: … Ibuprofen and famotidine ... Ibuprofen and Famotidine ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Famotidine ... Berkley and Jensen Famotidine ... Berkley and Jensen Acid Controller …
Matched Mixtures name: … Ibuprofen and famotidine ... Ibuprofen and Famotidine ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Famotidine ... Berkley and Jensen Famotidine ... Berkley and Jensen Acid Controller …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Displaying drugs 376 - 400 of 603 in total