Displaying drugs 376 - 400 of 721 in total
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (BCG ... It is one of the active ingredients in Anktiva, a combination product also containing [inbakicept], where …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (BCG ... It is one of the active ingredients in Anktiva, a combination product also containing [inbakicept], where …
Matched Categories: … Amino Acids, Peptides, and Proteins …
INO-4995
INO-4995 is an inositol tetrakisphosphate analog being investigated for Cystic Fibrosis.
Investigational
Matched Synonyms: … 2-O-butyryl-1-O-octyl-myo-Inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester …
Matched Iupac: … (1S,2S,3R,4R,5S,6R)-2,3,4,5-tetrakis({bis[(propanoyloxy)methoxy]phosphoryl}oxy)-6-(octyloxy)cyclohexyl …
Matched Iupac: … (1S,2S,3R,4R,5S,6R)-2,3,4,5-tetrakis({bis[(propanoyloxy)methoxy]phosphoryl}oxy)-6-(octyloxy)cyclohexyl …
6-o-Capryloylsucrose
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 6-O-(1-oxooctyl)-beta-D-fructofuranosyl …
Matched Name: … 6-o-Capryloylsucrose …
Matched Iupac: … 5S)-3,4-dihydroxy-5-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …
Matched Name: … 6-o-Capryloylsucrose …
Matched Iupac: … 5S)-3,4-dihydroxy-5-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …
Mucor circinelloides f. circinelloides
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
2-O-Methyl-beta-L-fucopyranose
Experimental
Matched Synonyms: … 6-Deoxy-2-O-methyl-β-L-galactopyranose ... 6-Deoxy-2-O-methyl-beta-L-galactopyranose …
Matched Name: … 2-O-Methyl-beta-L-fucopyranose …
Matched Name: … 2-O-Methyl-beta-L-fucopyranose …
2-O-methyl-alpha-L-fucopyranose
Experimental
Matched Synonyms: … 6-deoxy-2-O-methyl-α-L-galactopyranose ... 6-deoxy-2-O-methyl-alpha-L-galactopyranose …
Matched Name: … 2-O-methyl-alpha-L-fucopyranose …
Matched Name: … 2-O-methyl-alpha-L-fucopyranose …
Mangostin
Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … 7-o-methyl-.gamma.-mangostin ... 7-o-methyl-4-desprenylcostatin …
Matched Description: … Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Description: … Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. …
Luminol
Investigational
Matched Synonyms: … O-aminophthalylhydrazide ... O-aminophthaloyl hydrazide …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
3'-beta-Sialyl-beta-lactose
Experimental
Matched Synonyms: … O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose …
Matched Iupac: … }oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid ... 6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy …
Matched Iupac: … }oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid ... 6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy …
Orphenadrine
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Approved
Matched Synonyms: … N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine ... o-methyldiphenhydramine ... o-monomethyldiphenhydramine …
Matched Description: … A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm …
Matched Mixtures name: … MYOGESIC-O ... MYOGESIC-OR ... Orphenadrine Citrate, Aspirin and Caffeine …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Description: … A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm …
Matched Mixtures name: … MYOGESIC-O ... MYOGESIC-OR ... Orphenadrine Citrate, Aspirin and Caffeine …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Ivermectin
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … [15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one ... 24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy ... -2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S ... }-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3',7',19'-trioxaspiro[oxane ... 2-yl]-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy …
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... with statistical errors and accusations of plagiarism. ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents ... Compounds used in a research, industrial, or household setting …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... I-Dectin 0.5 % Pour-On ... Vimectin 0.5% w/v Pour On …
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... with statistical errors and accusations of plagiarism. ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents ... Compounds used in a research, industrial, or household setting …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... I-Dectin 0.5 % Pour-On ... Vimectin 0.5% w/v Pour On …
3-O-Methyl-d-glucose
Experimental
Matched Synonyms: … 3-O-Methylglucose ... O(3)-methyl-D-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Tofersen
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R ... Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Dextromethorphan
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Cold and Flu All In One ... Cold and Flu-IN-one Extra Strength ... Mucus Relief All In One Cold and Flu …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Heterocyclic Compounds with 4 or More Rings ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
Matched Mixtures name: … Cold and Flu All In One ... Cold and Flu-IN-one Extra Strength ... Mucus Relief All In One Cold and Flu …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Heterocyclic Compounds with 4 or More Rings ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
Lactulose
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Synonyms: … 4-O-beta-D-Galactopyranosyl-D-fructose ... 4-O-beta-D-Galactopyranosyl-D-fructofuranose …
Matched Iupac: … (2S,3R,4S,5R,6R)-2-{[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy}-6-(hydroxymethyl …
Matched Description: … List of Essential Medicines as one of the most effective and safe medicines employed in a health system ... for treating constipation and its efficacy in managing PSE may never be formally confirmed or refuted ... a readily available generic and brand-name non-prescription medication listed on the World Health Organization's …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Orb-lactulose …
Matched Iupac: … (2S,3R,4S,5R,6R)-2-{[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy}-6-(hydroxymethyl …
Matched Description: … List of Essential Medicines as one of the most effective and safe medicines employed in a health system ... for treating constipation and its efficacy in managing PSE may never be formally confirmed or refuted ... a readily available generic and brand-name non-prescription medication listed on the World Health Organization's …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Orb-lactulose …
Tyrosyladenylate
Experimental
Matched Synonyms: … 5'-O-(L-Tyrosylsulfamoyl)adenosine …
Matched Iupac: … 6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-(4-hydroxyphenyl)propan-1-one …
Matched Iupac: … 6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-(4-hydroxyphenyl)propan-1-one …
Desvenlafaxine
Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271]
MDD is a highly...
Approved
Investigational
Matched International brands: … Zyven-OD …
Matched Synonyms: … ODV ... O-desmethylvenlafaxine …
Matched Description: … 16% in the US alone and 12.8% in Europe. ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine ... Although the exact mechanism of pathophysiology is still unknown, imbalances or deficiencies of monoamines …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Synonyms: … ODV ... O-desmethylvenlafaxine …
Matched Description: … 16% in the US alone and 12.8% in Europe. ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine ... Although the exact mechanism of pathophysiology is still unknown, imbalances or deficiencies of monoamines …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Meradimate
Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Synonyms: … Menthyl-O-aminobenzoate …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products ... [T200] It is currently required to be named as meradimate in all FDA approved OTC products. ... Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 ... SPF 15 Spray-ON Sunscreen ... SPF 30+ Spray-ON Sunscreen …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products ... [T200] It is currently required to be named as meradimate in all FDA approved OTC products. ... Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 ... SPF 15 Spray-ON Sunscreen ... SPF 30+ Spray-ON Sunscreen …
Displaying drugs 376 - 400 of 721 in total