Displaying drugs 4076 - 4100 of 9917 in total
4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one
Experimental
Matched Name: … 4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one …
Matched Iupac: … 4-ethyl-5-methyl-2-(1H-1,2,3,4-tetrazol-5-yl)-2,3-dihydro-1H-pyrazol-3-one …
Matched Iupac: … 4-ethyl-5-methyl-2-(1H-1,2,3,4-tetrazol-5-yl)-2,3-dihydro-1H-pyrazol-3-one …
SC-74020
Experimental
Matched Iupac: … N-(4-{[(1R)-1-(hydroxycarbamoyl)-2-methylpropyl][2-(morpholin-4-yl)ethyl]sulfamoyl}phenyl)-4-pentylbenzamide …
L-756423
Experimental
Matched Iupac: … (2S)-4-[(1-benzofuran-2-yl)methyl]-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(2R)-2-hydroxy-2,3-dihydro-1H-inden ... -1-yl]carbamoyl}butyl]-N-tert-butylpiperazine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
OSI-7836
OSI-7836 is a member of the nucleoside class of cytotoxic drugs of which gemcitabine is the market leader. OSI Pharmaceuticals develops OSI-7836 as a next-generation gemcitabine. The anti-tumor activity of OSI-7836 appeares to be less schedule dependent than gemcitabine. It is also more active than ara-C (another clinically used nucleoside...
Investigational
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidine-2-thione …
L-778123
Experimental
Matched Iupac: … 4-[(5-{[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl}-1H-imidazol-1-yl)methyl]benzonitrile …
AZD-7687
AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AVI-7287
Investigational
SPK-7001
Investigational
tgAAG-76
tgAAG-76 consists of a recombinant adeno-associated virus (serotype 2) (rAAV2) gene transfer agent expressing RPE65.
Investigational
ALLO-715
ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).
Investigational
(11R)-10-acetyl-11-(2,4-dichlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Experimental
Matched Name: … 11-(2,4-dichlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1- …
Matched Iupac: … 9-acetyl-10-(2,4-dichlorophenyl)-4-hydroxy-14,14-dimethyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1( …
Matched Iupac: … 9-acetyl-10-(2,4-dichlorophenyl)-4-hydroxy-14,14-dimethyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1( …
(3r)-1-Acetyl-3-Methylpiperidine
Experimental
Matched Name: … (3r)-1-Acetyl-3-Methylpiperidine …
Matched Iupac: … 1-[(3R)-3-methylpiperidin-1-yl]ethan-1-one …
Matched Iupac: … 1-[(3R)-3-methylpiperidin-1-yl]ethan-1-one …
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Indopan
Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United...
Experimental
Illicit
Matched Synonyms: … 1-(1H-Indol-3-yl)-2-propanamine ... 3-(2-Aminopropyl)indole ... DL-3-(2-Aminopropyl)indole …
Matched Iupac: … 1-(1H-indol-3-yl)propan-2-amine …
Matched Iupac: … 1-(1H-indol-3-yl)propan-2-amine …
Pridopidine
Pridopidine has been used in trials studying the treatment of Huntington's Disease.
Investigational
Matched Iupac: … 4-(3-methanesulfonylphenyl)-1-propylpiperidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tapotoclax
Investigational
Matched Synonyms: … MCL-1 inhibitor AMG 176 ... MCL-1 inhibitor AMG-176 …
Matched Iupac: … (1S,3'R,6'R,7'S,8'E,11'S,12'R)-6-chloro-7'-methoxy-11',12'-dimethyl-3,4-dihydro-2H-20'-oxa-13'lambda6 ... -thia-1',14'-diazaspiro[naphthalene-1,22'-tetracyclo[14.7.2.0^{3,6}.0^{19,24}]pentacosane]-8',16'(25' …
Matched Iupac: … (1S,3'R,6'R,7'S,8'E,11'S,12'R)-6-chloro-7'-methoxy-11',12'-dimethyl-3,4-dihydro-2H-20'-oxa-13'lambda6 ... -thia-1',14'-diazaspiro[naphthalene-1,22'-tetracyclo[14.7.2.0^{3,6}.0^{19,24}]pentacosane]-8',16'(25' …
Fidrisertib
Investigational
Matched Synonyms: … (r)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo(1,2-b)pyridazin ... -b)pyridazin-4-yl)-, (3r)-tetrahydro-3-furanyl ester ... 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2 …
Matched Iupac: … (3R)-oxolan-3-yl 4-(6-{5-[4-ethoxy-1-(propan-2-yl)piperidin-4-yl]pyridin-2-yl}pyrrolo[1,2-b]pyridazin ... -4-yl)piperazine-1-carboxylate …
Matched Iupac: … (3R)-oxolan-3-yl 4-(6-{5-[4-ethoxy-1-(propan-2-yl)piperidin-4-yl]pyridin-2-yl}pyrrolo[1,2-b]pyridazin ... -4-yl)piperazine-1-carboxylate …
Vodudeutentan
Investigational
Matched Synonyms: … D-norleucine, n-((cis-2,6-di(methyl-d)-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)- …
Matched Iupac: … ]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid ... (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-di(2H1)methylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Iupac: … ]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid ... (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-di(2H1)methylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one
Experimental
Matched Name: … (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one …
Matched Iupac: … (12R)-12-(aminomethyl)-4-methoxy-8-thia-11,14-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),3,5-tetraen …
Matched Iupac: … (12R)-12-(aminomethyl)-4-methoxy-8-thia-11,14-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),3,5-tetraen …
Recifercept
Investigational
Matched Synonyms: … Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble ... Recombinant human fibroblast growth factor receptor 3 ... Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46) …
Zotiraciclib
Zotiraciclib is under investigation in clinical trial NCT02942264 (Zotiraciclib (TG02) Plus Dose-dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma).
Investigational
Matched Iupac: … (16E)-14-methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.1^{2,6}.1^{8,12}]heptacosa-1(24),2,4,6(27) …
GBR-12879
Investigational
Matched Synonyms: … Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propen-1-yl)- ... 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine ... Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)- …
Matched Iupac: … 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RO7300490
RO7300490 is an investigational Fibroblast Activation Protein-α (FAP) targeted CD40 agonist. RO7300490 is under investigation in clinical trial NCT04857138 (A Study to Evaluate Safety, Pharmacokinetics and Anti-tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in Participants With Advanced Solid Tumors).
Investigational
Displaying drugs 4076 - 4100 of 9917 in total