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Displaying drugs 4076 - 4100 of 10642 in total
Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Synonyms: … (+)-4-isopropenyl-1-methylcyclohexene ... (4R)-4-isopropenyl-1-methylcyclohexene ... (4R)-1-methyl-4-isopropenylcyclohex-1-ene …
Matched Iupac: … (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene …
Modufolin is under investigation for the treatment of Osteosarcoma.
Investigational
Matched Synonyms: … (6R,S)5,10-methylene-tetrahydrofolic acid ... D-N5,N10-METHYLENE-L-TETRAHYDROFOLIC ACID …
Matched Iupac: … (2S)-2-({4-[(6aR)-3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido …
Investigational
4SC-202 has been used in trials studying the treatment of Advanced Hematologic Malignancies.
Investigational
Matched Iupac: … (2E)-N-(2-aminophenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonyl]-1H-pyrrol-3-yl}prop-2-enamide …
4SC-203 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
Matched Iupac: … 1-(2-methoxy-5-methylphenyl)-3-[6-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl}amino …
AV-101 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
Matched Synonyms: … L-4-CL-KYN ... L-4-chlorokynurenine ... (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid …
Matched Iupac: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid …
Relmapirazin is under investigation in clinical trial NCT05425719 (Pharmacokinetics and Safety of MB-102 (Relmapirazin) and the Medibeacon Transdermal GFR Measurement System in Evaluation of Kidney Function in Normal and Renal Compromised Subjects).
Investigational
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … (S)-(4-hydroxyphenyl)glycine ... L-4-hydroxyphenylglycine ... L-2-(p-hydroxyphenyl)glycine …
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid …
Experimental
Matched Synonyms: … (S)-2,4-Diaminobutanoic acid ... L-Dbu ... L-2,4-Diaminobutanoate …
Matched Name: … L-2,4-diaminobutyric acid …
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Iupac: … 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12 …
Experimental
Matched Synonyms: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid ... L-kynurenine ... 3-Anthraniloyl-L-alanine …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
SB-649868 is under investigation in clinical trial NCT01030939 (Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers).
Investigational
Matched Iupac: … N-{[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl}-1-benzofuran-4
D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … ISA101 component D-3082-L ... ISA101B component D-3082-L ... Human Papilloma Virus (HPV) Type 16 E6/e7 Synthetic Long Peptide (SLP) Vaccine Component D-3082-L
Matched Name: … D-3082-L
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
ENTR-601-44 is an exon 44 skipping phosphorodiamidate morpholino oligonucleotide (PMO). Developed by Entrada Therapeutics, it was investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Experimental
Matched Synonyms: … (2S)-2-Amino-4-(S-methylsufonimidoyl)butanoic acid ... L-Methionine-S,R-sulfoximine ... BUTANOIC ACID, 2-AMINO-4-(S-METHYLSULFONIMIDOYL)-, (2S)- …
Matched Iupac: … (2S)-2-amino-4-[imino(methyl)oxo-lambda6-sulfanyl]butanoic acid …
Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic spindle formation and thus cell replication.
Experimental
Matched Synonyms: … (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10 …
Matched Iupac: … (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10 …
Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome....
Investigational
Matched Description: … at IL-6 Site 3. ... Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation ... Targeting IL-6 function can be achieved directly, or through interrupting the IL-6 receptor or gp130 …
Investigational
Matched Synonyms: … L-methionine-(s)-sulfoximine ... (2s)-2-amino-4-((s(s))-s-methylsulfonimidoyl)butanoic acid ... L-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine …
Matched Name: … Methionine sulfoximine, (S)- …
Matched Iupac: … (2S)-2-amino-4-[(S)-imino(methyl)oxo-lambda6-sulfanyl]butanoic acid …
Zetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).
Investigational
Matched Synonyms: … methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide ... (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4- …
Matched Iupac: … methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide ... (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4- …
Dordaviprone (ONC-201) is under investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma).
Investigational
Matched Synonyms: … 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin ... 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one …
Experimental
Matched Name: … (S)-2-Amino-3-(6h-Selenolo[2,3-B]-Pyrrol-4-Yl)-Propionic Acid …
Matched Iupac: … (2S)-2-amino-3-{6H-selenopheno[2,3-b]pyrrol-4-yl}propanoic acid …
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Synonyms: … (S)-4-(2-Amino-2-carboxyethyl)imidazole ... (S)-a-Amino-1H-imidazole-4-propanoic acid ... (S)-α-amino-1H-Imidazole-4-propanoic acid …
Matched Mixtures name: … AMINOACIDI S BIOINDUSTRIA L.I.M. ... NUTRINEAL PD-4 PERITONEAL DIALYSIS SOLUTION WITH 1.1% AMINO ACIDS ... NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
AUM-601 is a highly selective pan-TRK(tropomyosin receptor kinase). It is currently being investigated in clinical trials for the treatment of cancer.
Investigational
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Synonyms: … 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea ... N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Cibinetide has been used in trials studying the basic science of Depression.
Investigational
Matched Synonyms: … L-Pyr-L-Glu-L-Gln-L-Leu-L-Glu-L-Arg-L-Ala-L-Leu-L-Asn-L-Ser-L-Ser …
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S)-1-{[(1S)-2-carbamoyl-1-{ ... carbamoyl}butyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-4- …
Displaying drugs 4076 - 4100 of 10642 in total