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Displaying drugs 4151 - 4175 of 10623 in total
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Synonyms: … N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide …
Matched Iupac: … (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic …
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid ... L-3-Nitrotyrosine ... 3-Nitro-L-tyrosine …
Matched Name: … 3-nitro-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Experimental
Matched Synonyms: … 2,4,6-tris(1-aziridinyl)-s-triazine …
Investigational
Matched Name: … S-49076 …
Matched Iupac: … 3-{[(3Z)-3-({4-[(morpholin-4-yl)methyl]-1H-pyrrol-2-yl}methylidene)-2-oxo-2,3-dihydro-1H-indol-5-yl]methyl …
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Investigational
Matched Synonyms: … (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone ... S-Warfarin ... 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Name: … (S)-Warfarin …
Matched Iupac: … 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Description: … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared ... S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] …
Investigational
Trinitrotoluene is an explosive chemical that can cause skin irritation and other toxic consequences.
Experimental
Investigational
Investigational
Matched Synonyms: … 2-[4-(1-Methyl-4-pyridin-4-yl-lH-pyrazol-3-yl)-phenoxymethyl]-quinoline succinic acid …
Matched Iupac: … 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline …
Tempol has been used in trials studying the treatment of Anal Cancer.
Investigational
Matched Synonyms: … 4-OXYPIPERIDOL ... 2,2,6,6-TETRAMETHYL-4-HYDROXYPIPERIDINOOXY ... 1-PIPERIDINYLOXY,4-HYDROXY-2,2,6,6-TETRAMETHYL- …
Matched Iupac: … (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-yl)oxidanyl …
Mezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma).
Investigational
Matched Synonyms: … 4-(4-((4-(((2-((3s)-2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1h-isoindol-4- yl)oxy)methyl)phenyl)methyl ... Benzonitrile, 4-(4-((4-(((2-((3s)-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1h-isoindol-4-yl)oxy)methyl …
Matched Iupac: … 4-[4-({4-[({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}oxy)methyl]phenyl}methyl …
Investigational
Matched Synonyms: … 1,2,4-Triazolo(3,4-f)(1,6)naphthyridin-3(2H)-one, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl- ... 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one …
Matched Iupac: … 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H,3H-[1,2,4]triazolo[3,4-f]1,6-naphthyridin-3-one …
Investigational
Matched Synonyms: … L-valine, l-tyrosyl-l-leucyl-l-phenylalanyl-l-prolyl-l-glutaminyl-l-leucyl-l-isoleucyl-l-seryl- …
Investigational
Matched Synonyms: … Arg-ser-ser-cys-phe-gly-gly-arg-met-asp-arg-ile-gly-ala-gln-ser-gly-leu-gly-cys-asn-ser-phe-arg-tyr (cys 4- …
Investigational
Redasemtide is under investigation in clinical trial NCT05953480 (A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke).
Investigational
Matched Description: … investigation in clinical trial NCT05953480 (A Phase 2b, Randomized, Double-blind Study of Redasemtide (S- …
Investigational
Matched Synonyms: … (1e,6e)-1,7-bis(3,4-dimethoxyphenyl)-4-cyclobutylmethyl-1,6-heptadiene-3,5-dione ... (1e,6e)-4-(cyclobutylmethyl)-1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione ... 1,6-heptadiene-3,5-dione, 4-(cyclobutylmethyl)-1,7-bis(3,4-dimethoxyphenyl)-, (1e,6e)- …
Matched Iupac: … (1E,6E)-4-(cyclobutylmethyl)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione …
Investigational
Matched Synonyms: … L-Threonine, N-(1-oxotetradecyl)-L-α-glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl- …
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(2S)-6-amino-1-[(2S)-2-{[(1S,2R)-1-carboxy-2-hydroxypropyl ... carbamoyl}-3-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-methylpropyl]carbamoyl}ethyl]carbamoyl}-4- …
GDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
Investigational
Matched Synonyms: … 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amine …
Matched Iupac: … 5-[6,6-dimethyl-4-(morpholin-4-yl)-6H,8H,9H-[1,4]oxazino[3,4-h]purin-2-yl]pyrimidin-2-amine …
Experimental
Matched Name: … (1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl …
Matched Iupac: … {[(1R,2S,3R,5S,6R)-2,3,5-trihydroxy-4-{[hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-6-(phosphonooxy …
Investigational
Matched Iupac: … methyl 3-[(12R,13R,22S,23S)-17-(1-butoxyethyl)-4-butyl-12-ethyl-13,18,22,27-tetramethyl-3,5-dioxo-4,8,24,25,26 …
Experimental
Matched Name: … 5-[(3AS,4R,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANOIC ACID …
Matched Iupac: … 5-[(3aS,4R,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Biropepimut-S is under investigation in clinical trial NCT02873819 (Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral Cavity).
Investigational
Matched Synonyms: … Biropepimut-S
Matched Name: … Biropepimut-S
Matched Description: … Biropepimut-S is under investigation in clinical trial NCT02873819 (Safety and Efficacy Study of GL-0817 …
Displaying drugs 4151 - 4175 of 10623 in total