Displaying drugs 401 - 425 of 739 in total
Tarlatamab
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … [L50743] Tarlatamab-dlle was approved by the FDA in May 2024 for use in patients who have failed previous ... across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50743] Tarlatamab-dlle was approved by the FDA in May 2024 for use in patients who have failed previous ... across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Bismuth subsalicylate
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … Bismuth subsalicylate is an antacid and anti-diarrheal agent. ... to relieve nausea, diarrhea, and gastrointestinal discomfort. ... Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …
Lanolin
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... PETROLATUM and LANOLIN ... Vitamins A and D …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... PETROLATUM and LANOLIN ... Vitamins A and D …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Loratadine
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief ... Berkley and Jensen Allergy Relief …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief ... Berkley and Jensen Allergy Relief …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …
Mycogone nigra
Mycogone nigra allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Mycogone nigra whole …
Quercus acutissima whole
Quercus acutissima whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Sawtooth Oak Whole …
Matched Name: … Quercus acutissima whole …
Matched Description: … Quercus acutissima whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Name: … Quercus acutissima whole …
Matched Description: … Quercus acutissima whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Fructose-6-phosphate
Experimental
Matched Synonyms: … D-Fructose 6-phosphate ... keto-D-fructose 6-phosphate …
Matched Name: … Fructose-6-phosphate …
Matched Categories: … Sugar Phosphates …
Matched Name: … Fructose-6-phosphate …
Matched Categories: … Sugar Phosphates …
Dichlorvos
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved
Matched Synonyms: … 2,2-Dichloroethenyl dimethyl phosphate ... Dimethyl 2,2-dichlorovinyl phosphate ... Dimethyl-2,2-dichlorovinyl phosphate …
Matched Iupac: … 2,2-dichloroethenyl dimethyl phosphate …
Matched Description: … Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the _organophosphate_ class, frequently ... , and cancer. ... environmental and health concerns. …
Matched Iupac: … 2,2-dichloroethenyl dimethyl phosphate …
Matched Description: … Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the _organophosphate_ class, frequently ... , and cancer. ... environmental and health concerns. …
TMP
Experimental
Matched Synonyms: … 5-methyluridine 5'-phosphate ... ribothymidine 5'-phosphate ... ribosylthymine 5'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pyrethrum extract
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Acapatamab
Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and …
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …
D-glyceraldehyde 3-phosphate
An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Experimental
Matched Synonyms: … Glyceraldehyde-3-phosphate ... D-Glyceraldehyde 3-phosphate …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Lorigerlimab
Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND ... MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND …
Pyridoxal phosphate
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-phosphate ... Pyridoxal 5'-phosphate ... Pyridoxal phosphate anhydrous …
Matched Name: … Pyridoxal phosphate …
Matched Description: … phosphate (pyridoxamine). ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal …
Matched Salts name: … Pyridoxal phosphate hydrate …
Matched Categories: … pyridoxal phosphate ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Pyridoxal phosphate …
Matched Description: … phosphate (pyridoxamine). ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal …
Matched Salts name: … Pyridoxal phosphate hydrate …
Matched Categories: … pyridoxal phosphate ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Fosbretabulin
Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Synonyms: … Combretastatin A4 phosphate ... Combretastatin A-4 phosphate ... 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL)PHENYL DIHYDROGEN PHOSPHATE …
Triciribine phosphate
Investigational
Matched Synonyms: … Triciribine phosphate ... Pentaazaacenaphthylene-5' phosphate ester ... -D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLENE 5'-(DIHYDROGEN PHOSPHATE) …
Matched Name: … Triciribine phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Name: … Triciribine phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Estramustine phosphate
A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Synonyms: … Estramustine 17-(dihydrogen phosphate) …
Matched Name: … Estramustine phosphate …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Matched Name: … Estramustine phosphate …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Cephalosporium roseum
Cephalosporium roseum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Cephalosporium roseum whole …
Garcinia gummi-gutta fruit
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL-9718S
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tepilamide fumarate
Investigational
Matched Synonyms: … 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate …
Xylometazoline
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Dabocemagene autoficel
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND …
Displaying drugs 401 - 425 of 739 in total