Displaying drugs 4226 - 4250 of 9845 in total
S-(3-Iodobenzyl)glutathione
Experimental
Matched Name: … S-(3-Iodobenzyl)glutathione …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(3-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl} …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(3-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl} …
Daglutril
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Synonyms: … ((3S)-3-{1-((2R)-2-Ethoxycarbonyl-4-phenylbutyl)cyclopentanecarboxamido}-2-oxo-2,3,4,5-tetrahydro-1H- ... 1-benzazepin-1-yl)acetic acid …
Matched Iupac: … 2-[(3S)-3-{1-[(2R)-3-ethoxy-3-oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro ... -1H-1-benzazepin-1-yl]acetic acid …
Matched Iupac: … 2-[(3S)-3-{1-[(2R)-3-ethoxy-3-oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro ... -1H-1-benzazepin-1-yl]acetic acid …
(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
Experimental
Matched Name: … (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate …
ABT-341
ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different).
Experimental
Matched Synonyms: … TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE ... (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5- …
Matched Iupac: … )cyclohex-3-en-1-amine ... (1S,6R)-3-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl]-6-(2,4,5-trifluorophenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … )cyclohex-3-en-1-amine ... (1S,6R)-3-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl]-6-(2,4,5-trifluorophenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Opebacan
Investigational
Matched Synonyms: … 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
Profadol
Investigational
Matched Synonyms: … Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)- ... M-(1-methyl-3-propyl-3-pyrrolidinyl)phenol ... Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)- …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Irsenontrine
Irsenontrine is under investigation in clinical trial NCT03467152 (Study to Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies).
Investigational
Matched Synonyms: … 7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-((3s)-tetrahydrofuran-3-yl)-1,5-dihydro-4h-pyrazolo(4,3-c)quinolin ... -3-furanyl)- ... 4h-pyrazolo(4,3-c)quinolin-4-one, 1,5-dihydro-7-(2-methoxy-3,5-dimethyl-4- pyridinyl)-1-((3s)-tetrahydro …
Bisantrene
Investigational
Matched Iupac: … )hydrazin-1-yl]-4,5-dihydro-1H-imidazole ... 2-[(2E)-2-({10-[(E)-[2-(4,5-dihydro-1H-imidazol-2-yl)hydrazin-1-ylidene]methyl]anthracen-9-yl}methylidene …
(3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE
Experimental
Matched Iupac: … (3R,4S,5S,7R,9E,11R,12R)-12-ethyl-4-hydroxy-3,5,7,11-tetramethyl-1-oxacyclododec-9-ene-2,8-dione …
Bifidobacterium animalis lactis
Experimental
4'-nitrophenyl-3i-thiolaminaritrioside
Experimental
Divarasib
Investigational
Matched Synonyms: … -2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one ... -2-(((2S)-1-methyl-2-pyrrolidinyl)methoxy)-4-quinazolinyl)-3-methyl-1-piperazinyl)- ... 2-propen-1-one, 1-((3S)-4-((7R)-7-(6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl)-6-chloro-8-fluoro …
Omapatrilat
Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling. This drug from BMS was not approved by the FDA due...
Investigational
Matched Iupac: … (4S,7S,10aS)-5-oxo-4-[(2S)-3-phenyl-2-sulfanylpropanamido]-octahydro-2H-pyrido[2,1-b][1,3]thiazepine- …
Matched Description: … The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide
Experimental
Matched Name: … 2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide …
Matched Iupac: … 2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide …
Matched Iupac: … 2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide …
AVA-6000
Investigational
Matched Synonyms: … N-[(2R)-1-[(2S)-2-[(3-hydroxy-2-methyl-6-{[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11 ... -dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy}oxan-4-yl)carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl] …
Trazpiroben
Investigational
Matched Synonyms: … (3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8 triazaspiro(4.5) decan-3-yl)methyl)benzoic acid ... Benzoic acid, 3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro(4.5)dec-3-yl)methyl)- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PIK3CA
PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).
Investigational
Matched Synonyms: … Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform …
19-norandrostenedione
19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and mainly used by body builders. After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency.
In the...
Experimental
Illicit
Lisaftoclax
Lisaftoclax is a novel, orally active, selective and potent BCL-2 inhibitor
Investigational
Matched Synonyms: … 4-(4-((6-(4-chlorophenyl)spiro(3.5)non-6-en-7-yl)methyl)-piperazin-1-yl)-n-((3-nitro-4-(((2s)-1,4-dioxan ... 4-{4-{[6-(4-Chlorophenyl)spiro[3.5]non-6-en-7-yl]methyl}-piperazin-1-yl}-N-{{3-nitro-4-[((2S)-1,4-dioxan ... -2-ylmethyl)amino)-3-nitrophenyl)sulfonyl)-2-(1h-pyrrolo(2,3-b)pyridin-5-yloxy)- …
Matched Iupac: … methyl}amino)-3-nitrobenzenesulfonyl]-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide ... 4-(4-{[6-(4-chlorophenyl)spiro[3.5]non-6-en-7-yl]methyl}piperazin-1-yl)-N-[4-({[(2S)-1,4-dioxan-2-yl] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … methyl}amino)-3-nitrobenzenesulfonyl]-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide ... 4-(4-{[6-(4-chlorophenyl)spiro[3.5]non-6-en-7-yl]methyl}piperazin-1-yl)-N-[4-({[(2S)-1,4-dioxan-2-yl] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
fb-PMT
Investigational
Matched Synonyms: … 2-(4-(4-((1-(107- (4-(fluorophenyl)methoxy)-polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5 ... O,O'-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid ... O,O′-Bis({4-[3,5-diiodo-4-(1-methylen-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid …
BG-P-TAT
Investigational
Matched Synonyms: … 2-(4-(4-((1-(107-(4-(guanidinomethyl)phenoxy)-(polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)- …
3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol
Experimental
Matched Name: … 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol …
Matched Iupac: … 1-[(5S)-3-(2-chlorophenyl)-5-(3-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one …
Matched Iupac: … 1-[(5S)-3-(2-chlorophenyl)-5-(3-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one …
5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
Experimental
Matched Name: … 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …
Matched Iupac: … 5-(4-chloro-5-phenylthiophen-3-yl)-1lambda6,2,5-thiadiazolidine-1,1,3-trione …
Matched Iupac: … 5-(4-chloro-5-phenylthiophen-3-yl)-1lambda6,2,5-thiadiazolidine-1,1,3-trione …
Golexanolone
Investigational
Matched Synonyms: … Androstan-17-one, 3-ethynyl-3-hydroxy-, oxime, (3.beta.,5.alpha.,17e)- …
Matched Iupac: … (1E,3aS,3bR,5aS,7S,9aS,9bS,11aS)-7-ethynyl-1-(hydroxyimino)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Iupac: … (1E,3aS,3bR,5aS,7S,9aS,9bS,11aS)-7-ethynyl-1-(hydroxyimino)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Displaying drugs 4226 - 4250 of 9845 in total