Displaying drugs 4326 - 4350 of 5627 in total
SRT-1720
SRT-1720 is an activator of NAD(+)-dependent histone deacetylase SIRT1.
Investigational
Matched Synonyms: … 2-quinoxalinecarboxamide, n-(2-(3-(1-piperazinylmethyl)imidazo(2,1-b)thiazol-6-yl)phenyl)- ... N-(2-(3-(1-piperazinylmethyl)imidazo(2,1-b)thiazol-6-yl)phenyl)-2-quinoxalinecarboxamide …
Matched Iupac: … N-(2-{3-[(piperazin-1-yl)methyl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl)quinoxaline-2-carboxamide …
Matched Iupac: … N-(2-{3-[(piperazin-1-yl)methyl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl)quinoxaline-2-carboxamide …
Vismodegib
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Synonyms: … 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide ... Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)- …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Matched Description: … inhibiting the transmembrane protein smoothened homologue (SMO). ... Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and ... Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Matched Description: … inhibiting the transmembrane protein smoothened homologue (SMO). ... Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and ... Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
3-Fluoro-2-Methyl-Aniline
Experimental
Matched Name: … 3-Fluoro-2-Methyl-Aniline …
Matched Iupac: … 3-fluoro-2-methylaniline …
Matched Iupac: … 3-fluoro-2-methylaniline …
N-[3-(aminomethyl)benzyl]acetamidine
Experimental
Matched Name: … N-[3-(aminomethyl)benzyl]acetamidine …
Matched Iupac: … N-{[3-(aminomethyl)phenyl]methyl}ethanimidamide …
Matched Iupac: … N-{[3-(aminomethyl)phenyl]methyl}ethanimidamide …
2',3'-Dideoxythymidine-5'-Monophosphate
Experimental
Matched Name: … 2',3'-Dideoxythymidine-5'-Monophosphate …
Matched Iupac: … {[(2S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
3-Aminomethyl-Pyridinium-Adenine-Dinucleotide
Experimental
Matched Name: … 3-Aminomethyl-Pyridinium-Adenine-Dinucleotide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato ... }oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-(aminomethyl)-1lambda5-pyridin-1-ylium …
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato ... }oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-(aminomethyl)-1lambda5-pyridin-1-ylium …
GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE
Experimental
Matched Name: … GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE …
Matched Iupac: … [3,4-d][1,3]dioxol-2-yl]methyl}phosphonic acid ... {[(2R,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo …
Matched Iupac: … [3,4-d][1,3]dioxol-2-yl]methyl}phosphonic acid ... {[(2R,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo …
N-(pyridin-3-ylmethyl)aniline
Experimental
Matched Name: … N-(pyridin-3-ylmethyl)aniline …
Matched Iupac: … N-[(pyridin-3-yl)methyl]aniline …
Matched Iupac: … N-[(pyridin-3-yl)methyl]aniline …
N-(3-AMINOPROPYL)-2-NITROBENZENAMINE
Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
N-(3-carboxypropanoyl)-L-norvaline
N-(3-carboxypropanoyl)-L-norvaline is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom. This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase.
Experimental
Matched Name: … N-(3-carboxypropanoyl)-L-norvaline …
Matched Iupac: … (2S)-2-(3-carboxypropanamido)pentanoic acid …
Matched Description: … This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen ... This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase …
Matched Iupac: … (2S)-2-(3-carboxypropanamido)pentanoic acid …
Matched Description: … This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen ... This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase …
3'-THIO-THYMIDINE-5'-PHOSPHATE
Experimental
Matched Name: … 3'-THIO-THYMIDINE-5'-PHOSPHATE …
Matched Iupac: … acid ... {[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-sulfanyloxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … acid ... {[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-sulfanyloxolan-2-yl]methoxy}phosphonic …
Amotosalen
Investigational
Matched Synonyms: … 3-((2-aminoethoxy)methyl)-2,5,9-trimethyl-7h-furo(3,2-g)chromen-7-one ... 7h-furo(3,2-g)(1)benzopyran-7-one, 3-((2-aminoethoxy)methyl)-2,5,9-trimethyl- …
Matched Iupac: … 3-[(2-aminoethoxy)methyl]-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one …
Matched Salts name: … Amotosalen hydrochloride …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 3-[(2-aminoethoxy)methyl]-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one …
Matched Salts name: … Amotosalen hydrochloride …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Methotrimeprazine
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Synonyms: … (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine ... (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Salts cas: … 7104-38-3 ... 1236-99-3 …
Matched Salts name: … Methotrimeprazine hydrochloride …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Salts cas: … 7104-38-3 ... 1236-99-3 …
Matched Salts name: … Methotrimeprazine hydrochloride …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Navitoclax
Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others.
Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of...
Investigational
Matched Synonyms: … -1-Enylmethyl]-Piperazin-1-Yl}-Benzoyl)-3-Trifluoromethanesulfonylbenzenesulfonamide ... (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex …
Matched Iupac: … 1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3- …
Matched Description: … Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's ... Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among ... It is a substance being studied in the treatment of lymphomas and other types of cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3- …
Matched Description: … Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's ... Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among ... It is a substance being studied in the treatment of lymphomas and other types of cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
LDN-193189
Investigational
Matched Synonyms: … 4-(6-(4-(piperazin-1-yl)phenyl_pyrazolo[1,5-a]pyrimidin-3-yl)quinoline ... Quinoline, 4-(6-(4-(1-piperazinyl)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)- …
Matched Iupac: … 4-{6-[4-(piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl}quinoline …
Matched Iupac: … 4-{6-[4-(piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl}quinoline …
Magrolimab
Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g4-kappa, anti-(homo sapiens cd47 (integrin associated protein, iap, mer6, oa3)), monoclonal ... antibodygamma4 heavy chain (1-444) (vh (homo sapiens ighv1-3*01 (87.8%)-(ighd)-ighj4*01 (100%)) (8.8.10 …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium
Experimental
Matched Name: … [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium …
Matched Iupac: … N-[3-(dimethyl-oxo-$l^{5}-azanyl)propyl]dodecanamide …
Matched Iupac: … N-[3-(dimethyl-oxo-$l^{5}-azanyl)propyl]dodecanamide …
3'-Phosphate-Adenosine-5'-Diphosphate
Experimental
Matched Name: … 3'-Phosphate-Adenosine-5'-Diphosphate …
Matched Iupac: … )oxy]phosphonic acid ... [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Iupac: … )oxy]phosphonic acid ... [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Experimental
Matched Name: … Di-Stearoyl-3-Sn-Phosphatidylethanolamine …
Matched Iupac: … (2-aminoethoxy)[(2S)-2,3-bis(octadecanoyloxy)propoxy]phosphinic acid …
Matched Iupac: … (2-aminoethoxy)[(2S)-2,3-bis(octadecanoyloxy)propoxy]phosphinic acid …
3-(Benzyloxy)Pyridin-2-Amine
Experimental
Matched Name: … 3-(Benzyloxy)Pyridin-2-Amine …
Matched Iupac: … 3-(benzyloxy)pyridin-2-amine …
Matched Iupac: … 3-(benzyloxy)pyridin-2-amine …
3-Aza-2,3-Dihydrogeranyl Diphosphate
Experimental
Matched Name: … 3-Aza-2,3-Dihydrogeranyl Diphosphate …
Matched Iupac: … ({2-[methyl(4-methylpent-3-en-1-yl)amino]ethyl phosphonato}oxy)phosphonate …
Matched Iupac: … ({2-[methyl(4-methylpent-3-en-1-yl)amino]ethyl phosphonato}oxy)phosphonate …
2',3'-Dideoxycytidine-5'-Monophosphate
Experimental
Matched Name: … 2',3'-Dideoxycytidine-5'-Monophosphate …
Matched Iupac: … {[(2S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
3-Amino-6-Hydroxy-Tyrosine
Experimental
Matched Name: … 3-Amino-6-Hydroxy-Tyrosine …
Matched Iupac: … (2S)-2-amino-3-(5-amino-2,4-dihydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(5-amino-2,4-dihydroxyphenyl)propanoic acid …
4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline
Experimental
Matched Name: … 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline …
Matched Iupac: … 6,7-dimethoxy-N-[3-(methylsulfanyl)phenyl]quinazolin-4-amine …
Matched Iupac: … 6,7-dimethoxy-N-[3-(methylsulfanyl)phenyl]quinazolin-4-amine …
Displaying drugs 4326 - 4350 of 5627 in total