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Displaying drugs 4351 - 4375 of 8653 in total

5-Nitro-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione

Experimental
Matched Name: … 5-Nitro-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione …
Matched Iupac: … 5-nitro-6-{[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione …

2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE

Experimental
Matched Name: … 2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE …
Matched Iupac: … (2S)-2-amino-3-{2,4-dihydroxy-5-[(E)-(2-phenylethylidene)amino]phenyl}propanoic acid …

4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid

Experimental
Matched Name: … 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid …
Matched Iupac: … 4-{5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acid …

2,3-Dicarboxy-4-(2-Chloro-Phenyl)-1-Ethyl-5-Isopropoxycarbonyl-6-Methyl-Pyridinium

Experimental
Matched Name: … 2,3-Dicarboxy-4-(2-Chloro-Phenyl)-1-Ethyl-5-Isopropoxycarbonyl-6-Methyl-Pyridinium …
Matched Iupac: … 2,3-dicarboxy-4-(2-chlorophenyl)-1-ethyl-6-methyl-5-[(propan-2-yloxy)carbonyl]pyridin-1-ium …

N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid

Experimental
Matched Name: … N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl ... )-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid …
Matched Iupac: … (2S)-2-({4-[(2E)-N-({2-amino-4-oxo-1H,4H-pyrido[3,2-d]pyrimidin-6-yl}methyl)-3-{4-carbamoyl-1-[(2R,3R ... ,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido …

4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide

Experimental
Matched Name: … 4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide …
Matched Iupac: … 4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]-[1,1'-biphenyl]-3-carboxamide …

EVT 201

EVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being developed as a treatment for insomnia. It is being developed by Evotec Inc.
Investigational
Matched Iupac: … }]tetradeca-1(10),3,5,11,13-pentaen-9-one ... 11-chloro-5-{5-[(dimethylamino)methyl]-1,2,4-oxadiazol-3-yl}-8-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6 …

Ribitol

Experimental

ATYR-1940

Investigational

Ifenprodil

N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Iupac: … 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ilginatinib

NS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, and Post-Essential Thrombocythemia Myelofibrosis.
Investigational
Matched Synonyms: … (S)-N-(1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N'-(PYRAZIN-2-YL)PYRIDINE-2,6-DIAMINE ... 2,6-PYRIDINEDIAMINE, N2-((1S)-1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N6-2-PYRAZINYL- …
Matched Iupac: … N2-[(1S)-1-(4-fluorophenyl)ethyl]-4-(1-methyl-1H-pyrazol-4-yl)-N6-(pyrazin-2-yl)pyridine-2,6-diamine …

Icerguastat

Investigational
Matched Synonyms: … Sephin 1 ... Sephin-1 …

Inhibitor Idd 384

Experimental

Cinitapride

Cinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.
Investigational
Matched Synonyms: … 4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamide …
Matched Iupac: … 4-amino-N-{1-[(cyclohex-3-en-1-yl)methyl]piperidin-4-yl}-2-ethoxy-5-nitrobenzamide …
Matched Description: … Cinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5- ... HT4 receptors and antagonist activity at 5-HT2 receptors. …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …

Sovesudil

Investigational
Matched Synonyms: … (1,1'-biphenyl)-3-carboxylic acid, 2'-(aminomethyl)-5'-(((3-fluoro-4-pyridinyl)amino)carbonyl)-, propyl …

Sudapyridine

Sudapyridine is under investigation in clinical trial NCT05824871 (Sudapyridine (WX-081) in Rr/mdr/xdr-tuberculosis Patients).
Investigational
Matched Synonyms: … 3-Pyridineethanol, 5-(4-chlorophenyl)-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl- ... αS,βR)-5-(4-Chlorophenyl)-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-pyridineethanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

DR-01

DR-01 is a monoclonal antibody directed against human CD94.
Investigational

HH-009

HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational

7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE

Experimental
Matched Name: … 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE …
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-methyloxolane-3,4-diol …

GYM329

GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational

RG-7795

Investigational
Matched Iupac: … (2R,3R,5S)-2-{5-amino-2-oxo-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolan-3-yl acetate …

Galegenimab

Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … igg1 fab fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal fhtr2163 .gamma.1- …

Proscillaridin

Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations and triggering cell...
Experimental
Matched Iupac: … 5-[(1S,2R,5S,10R,11S,14S,15R)-11-hydroxy-2,15-dimethyl-5-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan …
Matched Description: … anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I …

BNT162b3

The BNT162b3 vaccine is the latest addition to BioNTech and partner Pfizer’s mRNA COVID-19 vaccine program. Similar to BNT162b2, BNT162b3 uses a nucleoside-modified RNA (modRNA) technology. Pfizer and BioNTech deemed this compound as promising in preclinical trials and have decided to initiate further testing of it. As such, BNT162b3 has...
Investigational
Matched Description: … As such, BNT162b3 has entered a phase I/II study in early September 2020 (NCT04537949). …

N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE

Experimental
Matched Name: … N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …
Displaying drugs 4351 - 4375 of 8653 in total