Sovesudil

DB18812InvestigationalSmall molecule

Sovesudil: Overview.

Mechanism: Pharmacologically active on Rho-associated protein kinase 1 and Rho-associated protein kinase 2
Curator reviewed
Formula / weight: C₂₃H₂₂FN₃O₃ · 407.445 g/mol (avg)
Code names: AMA-0076 · PHP-201

Resolves to

Compound

Structure

InChIKeyPNWBYIFLWUCWKS-UHFFFAOYSA-NSMILESCCCOC(=O)C1=CC=CC(=C1)C1=CC(=CC=C1CN)C(=O)NC1=CC=NC=C1F

Targets

What you can answer from here — as of July 09, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Sovesudil, and which of those have an active Phase 3 trial?

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