Sovesudil

Identification

Generic Name
Sovesudil
DrugBank Accession Number
DB18812
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 407.445
Monoisotopic: 407.164519743
Chemical Formula
C23H22FN3O3
Synonyms
  • (1,1'-biphenyl)-3-carboxylic acid, 2'-(aminomethyl)-5'-(((3-fluoro-4-pyridinyl)amino)carbonyl)-, propyl ester
  • Sovesudil
External IDs
  • AMA-0076
  • AMA0076
  • PHP-201
  • PHP201

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
C23O3R93BM
CAS number
1333400-14-8
InChI Key
PNWBYIFLWUCWKS-UHFFFAOYSA-N
InChI
InChI=1S/C23H22FN3O3/c1-2-10-30-23(29)17-5-3-4-15(11-17)19-12-16(6-7-18(19)13-25)22(28)27-21-8-9-26-14-20(21)24/h3-9,11-12,14H,2,10,13,25H2,1H3,(H,26,27,28)
IUPAC Name
SMILES
CCCOC(=O)C1=CC=CC(=C1)C1=CC(=CC=C1CN)C(=O)NC1=CC=NC=C1F

References

General References
Not Available
ChemSpider
30840182
BindingDB
50442825
ChEMBL
CHEMBL2440750

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
3Unknown StatusTreatmentOcular Hypertension / Ocular Hypertension, Primary Open-angle Glaucoma (POAG)1somestatusstop reasonjust information to hide
2CompletedTreatmentEye Diseases / Glaucoma / Ocular Hypertension2somestatusstop reasonjust information to hide
2CompletedTreatmentNormal Tension Glaucoma (NTG)1somestatusstop reasonjust information to hide
1CompletedBasic ScienceHealthy Volunteers (HV)1somestatusstop reasonjust information to hide
1CompletedTreatmentEye Diseases / Glaucoma / Ocular Hypertension1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 24, 2024 02:17 / Updated at June 24, 2024 02:49