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Displaying drugs 426 - 450 of 8170 in total

Damoctocog alfa pegol

In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational

Ergosterol

A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental

Hydroxyamphetamine

Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is indirect sympathomimetic agent which cause dilation of the eye pupil before diagnostic test. Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry...
Approved
Matched Synonyms: … 4-hydroxyamphetamine ... 4-(2-aminopropyl)phenol ... dl-4-hydroxyamphetamine …
Matched Iupac: … 4-(2-aminopropyl)phenol …

Dihydro-alpha-ergocryptine

Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Iupac: … [7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14 ... -tetraene-4-carboxamide ... (2R,4R,7R)-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …

Tildrakizumab

Tildrakizumab is a high-affinity, humanized, IgG1 κ antibody targeting interleukin 23 p19 that shows promise in the evolution of treatment strategy in chronic plaque psoriasis . The Food and Drug Administration (FDA) approved ILUMYA (tildrakizumab-asmn) for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy...
Approved
Investigational
Matched Description: … The approved recommended dosage of ILUMYA is a subcutaneous injection of 100 mg at Weeks 0, 4, and every …

Dostarlimab

Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Description: … Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed …

Dichlorobenzyl alcohol

Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Salts cas: … 137-08-6 …
Matched Mixtures name: … Irospan 24/6 ... Irospan 24/6 ... Pregvit Folic 4 …
Matched Products: … แพนโทธีนิค 200 (วิตามินบี5) …

Ethynodiol diacetate

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Synonyms: … 17α-Ethynylestr-4-ene-3β,17β-diol acetate ... 3β, 17β-Diacetoxy-17α-ethynyl-4-oestrene ... 17α-Ethynyl-4-estrene-3β,17β-diol diacetate …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Mixtures name: … MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 50 G …
Matched Products: … MAJEZIK %5 TOPIKAL JEL, 30 G ... MAJEZIK %5 TOPIKAL JEL, 50 G ... MAJEZIK % 5 TOPIKAL SPREY, ÇÖZELTİ, 50 ML …

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Synonyms: … 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine ... 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Salts cas: … 32795-47-4 …

Posaconazole

Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Iupac: … 4-{4-[4-(4-{[(3R,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methoxy}phenyl ... )piperazin-1-yl]phenyl}-1-[(2S,3S)-2-hydroxypentan-3-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one …

Technetium Tc-99m pertechnetate

Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … Technetium-99m's short half life (6 hours) makes storage impossible, therefore it is supplied as its …
Matched Products: … MON.TEK 99 MO/99MTC JENERATÖR, 5 GBQ …

Zaleplon

Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Products: … SONATA ® 5 MG. CAPSULAS …

Oteracil

Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … 5-azaorotic acid …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, 5- …

Imatinib

Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Synonyms: … α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 1-phenethyl-4-N-propionylanilinopiperidine ... 1-Phenethyl-4-(N-phenylpropionamido)piperidine ... N-(1-phenethyl-4-piperidyl)propionanilide …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Salts cas: … 1443-54-5 …
Matched Products: … DUROGESIC 12 MCG/SAAT TRANSDERMAL FLASTER, 5 ADET ... DUROGESIC 100 MCG/SAAT TRANSDERMAL FLASTER, 5 ADET ... DUROGESIC 25 MCG MCG/SAAT TRANSDERMAL FLASTER, 5 ADET …

Ebola Zaire vaccine (live, attenuated)

Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved

Viltolarsen

Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational

Repaglinide

Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Repaglinide induces an early insulin response to meals decreasing postprandial blood...
Approved
Investigational
Matched Iupac: … 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid …
Matched Products: … Repaglinid STADA 4 mg Tabletten ... Repaglinid Sandoz 4 mg - Tabletten …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Synonyms: … N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine …
Matched Iupac: … 7-chloro-N-[5-(diethylamino)pentan-2-yl]quinolin-4-amine …
Matched Salts cas: … 50-63-5 …
Matched Products: … OROQUİNE 250 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ , 10 ADET …

Diaminopyrimidine oxide

Diaminopyrimidine oxide is a compound similar to minoxidil which is used to aid in hair growth.
Approved

Olopatadine

Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … -2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-5- …
Matched Salts cas: … 140462-76-6 …
Matched Products: … OFNOL %0,1 STERIL OFTALMIK COZELTI, 5 ML ... NIANCO %0,1 STERIL OFTALMIK COZELTI, 5 ML ... OLOPATADINE HYDROCHLORIDE TABLETS 5 MG MEIJI …

Buclizine

Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Synonyms: … 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine …
Matched Iupac: … 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)(phenyl)methyl]piperazine …

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Synonyms: … 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine …
Matched Iupac: … 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14 …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Loxapine-5 ... Loxapine Succinate Tablets 5 mg ... ADASUVE 9,1 MG İNHALASYON İÇİN KULLANIMA HAZIR TOZ, 5 ADET …
Displaying drugs 426 - 450 of 8170 in total