Displaying drugs 426 - 450 of 705 in total
Cyclo(prolylglycyl)
Experimental
Matched Synonyms: … Cyclo(pro-O-gly) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
cis-tetracosenoyl sulfatide
Experimental
Matched Synonyms: … 1-(3-O-sulfo-beta-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]sphingosine …
Matched Iupac: … ,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy …
Matched Iupac: … ,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy …
AB-201
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Name: … OTL-102 …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells ... It is being investigated for the treatment of X-linked chronic granulomatous disease. …
Matched Name: … OTL-102 …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells ... It is being investigated for the treatment of X-linked chronic granulomatous disease. …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Matched Description: … These are heat inactivated and purified. …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this ... TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. ... various degrees of organ damage. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
Matched Description: … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this ... TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. ... various degrees of organ damage. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
RU84687
RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
Experimental
Matched Synonyms: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-2-O-{2-[(piperidin-3- ... ylmethyl)amino]ethyl}-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside …
Matched Name: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin ... -3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside …
Matched Iupac: … }-5-(hydroxymethyl)-3-(2-{[(piperidin-3-yl)methyl]amino}ethoxy)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy ... )-4,6-diamino-2-{[(2S,3R,4R,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy …
Matched Name: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin ... -3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside …
Matched Iupac: … }-5-(hydroxymethyl)-3-(2-{[(piperidin-3-yl)methyl]amino}ethoxy)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy ... )-4,6-diamino-2-{[(2S,3R,4R,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy …
Butylidenephthalide
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …
OTL-203
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Name: … OTL-203 …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Matched Name: … OTL-203 …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH ... N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN AVERAGE OFAPPROXIMATELY ... -METHOXYPOLY(O …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Iupac: … amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy ... }-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide …
Matched Description: … of breath and the coughing up of blood. ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin …
Matched Iupac: … amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy ... }-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide …
Matched Description: … of breath and the coughing up of blood. ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin …
Mitotane
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … o,p'-DDD …
Matched Description: … metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their ... It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... used off-label for the management of Cushing's syndrome. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their ... It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... used off-label for the management of Cushing's syndrome. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
WP-1122
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). ... It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361] …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). ... It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361] …
3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
Experimental
Matched Name: … 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME …
Methylcellulose
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … and emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and ... [A253277] Several serogroups of _N. meningitidis_ - A, B, C, Y, and W-135 - known to cause meningococcal ... _ CRM197 protein carrier, resulting in four drug substances contained in each dose of vaccine. …
Matched Description: … invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and ... [A253277] Several serogroups of _N. meningitidis_ - A, B, C, Y, and W-135 - known to cause meningococcal ... _ CRM197 protein carrier, resulting in four drug substances contained in each dose of vaccine. …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched International brands: … Omnatax-O …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Bitolterol
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … 4-(2-(tert-butylamino)-1-hydroxyethyl)-o-phenylene di-p-toluate ... 4-[2-(tert-butylamino)-1-hydroxyethyl]-o-phenylene di-p-toluate …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Gemcitabine elaidate
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine ... 5'-O-(TRANS-9''-OCTADECENOYL)-1-.BETA.-D-2'DEOXY-2',2'-DIFLUOROCYTIDINE …
Matched Iupac: … [(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl (9E) …
Matched Description: … Lung Cancer, and Metastatic Pancreatic Adenocarcinoma. ... Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … [(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl (9E) …
Matched Description: … Lung Cancer, and Metastatic Pancreatic Adenocarcinoma. ... Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Povidone-iodine
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Shelanski and M. V. Shelanski. ... It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. …
Matched Mixtures name: … Prevail One Step ... Point Of Care Kit KM ... Point Of Care LM 2.2 …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Easy to break-off cleaning and disinfecting swabstick DFB-I ... Alpha One ... Povi-One …
Matched Mixtures name: … Prevail One Step ... Point Of Care Kit KM ... Point Of Care LM 2.2 …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Easy to break-off cleaning and disinfecting swabstick DFB-I ... Alpha One ... Povi-One …
Tavokinogene telseplasmid
Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
Matched Synonyms: … separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus ... Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are …
Matched Description: … Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12. …
Matched Description: … Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12. …
APD-209
Investigational
Matched Synonyms: … -neuraminic acid, n-acetyl-2-o-(7,26-dioxo-10,13,16,19,22-pentaoxa-6,25-diazapentaconta-35,37-diyn-1- …
Displaying drugs 426 - 450 of 705 in total