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Displaying drugs 4701 - 4725 of 10619 in total
Investigational
Matched Categories: … Diagnostic Uses of Chemicals …
LU-31130 is a rapid acting therapy developed by H. Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. It acts at the Dopamine D4 receptors in the cortex and has low affinity for D2 receptors, adrenoceptors, muscarinic and histaminergic receptors. It provides anti-psychotic characteristic and a low incidence of extrapyramidal...
Investigational
Matched Description: … Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. ... It provides anti-psychotic characteristic and a low incidence of extrapyramidal and cardiovascular side …
Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm...
Experimental
Matched Description: … Experiments of mesterolone serving as a potential treatment of depression are still undergoing. ... Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT ... Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH [A27177, A27178 …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Vet approved
Matched Iupac: … (1'R,2R,4'S,5S,6R,8'R,10'E,13'R,14'E,16'E,20'R,21'Z,24'S)-24'-hydroxy-21'-(hydroxyimino)-5,6,11',13', ... oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S, ... 5S,6R,8'R,10'E,13'R,14'E,16'E,20'R,21'Z,24'S)-6-ethyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl …
Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more potent than this drug.
Illicit
Matched Description: … Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Trimegestone has been used in trials studying the treatment of Postmenopause.
Investigational
Matched Description: … Trimegestone has been used in trials studying the treatment of Postmenopause. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Illicit
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …
PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors.
Investigational
Matched Description: … PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors. …
Experimental
Illicit
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
Experimental
Illicit
Matched Description: … An opioid analgesic structurally related to methadone and used in the treatment of severe pain. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Investigational
Matched Iupac: … (4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-5',15'-dioxa-2' …
Matched Description: … Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea. …
Oxaprotiline is a norepinephrine reuptake inhibitor of the tetracyclic antidepressant family that is related to maprotiline. This drug was never marketed. Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). Dextroprotiline is the S or dextro isomer of...
Experimental
Matched Description: … Dextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A). ... Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). ... Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Description: … Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult …
Matched Categories: … Diagnostic Uses of Chemicals …
The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Investigational
Matched Description: … The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein …
Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
Investigational
Matched Description: … Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic. …
Matched Categories: … Antivirals for treatment of HCV infections …
Experimental
Matched Categories: … Ethers of Tropine or Tropine Derivatives …
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … results in the expression of S protein by human cells. ... INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development ... Furthermore, the antibodies produced were capable of inhibiting the binding of SARS-CoV-2 to the ACE2 …
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Experimental
Matched Categories: … Drugs for Treatment of Bone Diseases …
Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Description: … Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective ... in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase …
Matched Mixtures name: … Senna-S ... Senexon-S ... Senna-S
SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. As of June 2020, the company is pursuing a...
Investigational
Matched Description: … SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID ... ) to test the safety and immunogenicity of the vaccine. ... As of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908 …
Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein . It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults...
Investigational
Matched Description: … the S-protein[A226588]. ... 1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of ... It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide …
Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.
Withdrawn
Matched Description: … It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 4701 - 4725 of 10619 in total