Lofentanil

DB09174ExperimentalIllicitSmall molecule

Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more...

Chemical structure of Lofentanil
Formula / weight
C25H32N2O3 · 408.542 g/mol (avg)

Resolves to

Structure
InChIKeyIMYHGORQCPYVBZ-NLFFAJNJSA-NSMILESCCC(=O)N(C1=CC=CC=C1)[C@]1(CCN(CCC2=CC=CC=C2)C[C@H]1C)C(=O)OC

What you can answer from here — as of March 06, 2025

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
920Drug interactionsStructured to mechanism, not free text
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7+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Lofentanil, and which of those have an active Phase 3 trial?

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