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Displaying drugs 4776 - 4800 of 10623 in total

Troriluzole

Troriluzole is under investigation in clinical trial NCT03701399 (Troriluzole in Adult Subjects With Spinocerebellar Ataxia).
Investigational
Matched Iupac: … 2-amino-N-{[methyl({[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]carbamoyl}methyl)carbamoyl]methyl}acetamide …

ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE

Experimental
Matched Iupac: … (2R,3R,4S,5R,6S)-2-methyl-6-(2-nitrophenoxy)oxane-3,4,5-triol …

Aspartame

Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid.
Investigational
Nutraceutical
Matched Synonyms: … 1-Methyl N-L-alpha-aspartyl-L-phenylalanate ... 1-methyl N-L-α-aspartyl-L-phenylalanate ... L-Aspartyl-L-phenylalanine methyl ester …

5,6-dihydro-5-azacytidine

Investigational
Matched Synonyms: … 1,3,5-triazin-2(1h)-one, 4-amino-5,6-dihydro-1-.beta.-d-ribofuranosyl- …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,5,6-tetrahydro-1,3,5-triazin …

Digalactosyl Diacyl Glycerol (Dgdg)

Experimental
Matched Iupac: … (2S)-1-(octadecanoyloxy)-3-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy ... -6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}propan-2-yl octadecanoate …

Abacavir hydroxyacetate

Prurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis.
Investigational
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methyl 2-hydroxyacetate …

N-(biphenyl-4-ylsulfonyl)-D-leucine

Experimental
Matched Name: … N-(biphenyl-4-ylsulfonyl)-D-leucine …
Matched Iupac: … (2R)-2-{[1,1'-biphenyl]-4-sulfonamido}-4-methylpentanoic acid …

Danburstotug

Danburstotug is under investigation in clinical trial NCT04809012 (Study of STI-3031 in Patients With Selected Relapsed or Refractory Solid Tumors).
Investigational

Letolizumab

Letolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy in Adult Subjects With ITP).
Investigational

Domatinostat

Withdrawn
Matched Synonyms: … (e)-n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)acrylamide ... 2-propenamide, n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)- …
Matched Iupac: … (2E)-N-(2-aminophenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonyl]-1H-pyrrol-3-yl}prop-2-enamide …

SB-218078

SB-218078 is a specific inhibitor of CHK1.
Investigational
Matched Iupac: … 4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6) …

Recilisib

Investigational
Matched Synonyms: … 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)benzoic acid ... Benzoic acid, 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)- …
Matched Iupac: … 4-[(1E)-2-[(4-chlorophenyl)methanesulfonyl]ethenyl]benzoic acid …

RI 624

RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain. RI 624 is being developed by Rinat and is currently in Phase I clinical trials.
Investigational

N-6022

N6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis.
Investigational
Matched Iupac: … 3-[1-(4-carbamoyl-2-methylphenyl)-5-[4-(1H-imidazol-1-yl)phenyl]-1H-pyrrol-2-yl]propanoic acid …

Onvansertib

Onvansertib is under investigation in clinical trial NCT03303339 (Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML).).
Investigational
Matched Synonyms: … 1-(2-Hydroxyethyl)-8-((5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl)amino)-4,5-dihydro-1H-pyrazolo …
Matched Iupac: … 1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo …

Tolinapant

ASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Iupac: … 1-{6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-1-yl}-2-[ ... (2R,5R)-5-methyl-2-{[(3R)-3-methylmorpholin-4-yl]methyl}piperazin-1-yl]ethan-1-one …
Matched Salts name: … Tolinapant L-(+)-lactic acid …

Lawsone

Experimental

Dibenzofuran-4,6-Dicarboxylic Acid

Experimental

ST-101

ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational

Calcium hypochlorite

Experimental

2-Hydroxy-5-({1-[(2-Naphthyloxy)Methyl]-3-Oxoprop-1-Enyl}Amino)Tyrosine

Experimental
Matched Synonyms: … 2-Hydroxy-5-{[(2E)-1-(2-naphthyloxy)-4-oxo-2-buten-2-yl]amino}-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(2,4-dihydroxy-5-{[(2E)-1-(naphthalen-2-yloxy)-4-oxobut-2-en-2-yl]amino}phenyl)propanoic …

DSP107

DSP107 is a bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4-1BBL.
Investigational
Matched Synonyms: … SIRPα -4-1BBL …
Matched Description: … bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4- …

S-(D-Carboxybutyl)-L-Homocysteine

Experimental
Matched Name: … S-(D-Carboxybutyl)-L-Homocysteine …

Recombinant soluble human CD4

Investigational

Lorundrostat

Lorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension).
Investigational
Matched Synonyms: … 1-Piperazineacetamide, N-[trans-4-(acetylamino)cyclohexyl]-4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]- ... N-(trans-4-acetamidocyclohexyl)-2-{4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]piperazin-1-yl}acetamide …
Displaying drugs 4776 - 4800 of 10623 in total