Displaying drugs 4776 - 4800 of 11857 in total
GI-181771X
Gski181771 X is under investigation in clinical trial NCT00600743 (Effect of a CCK-1R Agonist on Food Intake in Humans).
Investigational
Matched Description: … Gski181771 X is under investigation in clinical trial NCT00600743 (Effect of a CCK-1R Agonist on Food …
Matched Categories: … Receptor, Cholecystokinin A, agonists …
Matched Categories: … Receptor, Cholecystokinin A, agonists …
Mesterolone
Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm...
Experimental
Matched Iupac: … (1S,3aS,3bR,5aS,9S,9aS,9bS,11aS)-1-hydroxy-9,9a,11a-trimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
Matched Description: … It is not a substrate for aromatase so it is not converted into estrogen. ... Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT ... Experiments of mesterolone serving as a potential treatment of depression are still undergoing. …
Matched Description: … It is not a substrate for aromatase so it is not converted into estrogen. ... Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT ... Experiments of mesterolone serving as a potential treatment of depression are still undergoing. …
Stanolone acetate
Stanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.
Experimental
Matched Iupac: … (1S,3aS,3bR,5aS,9aS,9bS,11aS)-9a,11a-dimethyl-7-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … Stanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was …
Matched Description: … Stanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was …
Navoximod
Navoximod is under investigation in clinical trial NCT02048709 (Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors).
Investigational
Matched Iupac: … (1R,4r)-4-[(1R)-2-[(5S)-6-fluoro-5H-imidazo[4,3-a]isoindol-5-yl]-1-hydroxyethyl]cyclohexan-1-ol …
AICA ribonucleotide
5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has been used clinically to treat and protect against cardiac ischemic injury. The drug was first used in the 1980s as...
Experimental
Investigational
Matched Description: … is currently of interest as a potential treatment for diabetes by increasing the metabolic activity ... The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and …
Vitex agnus-castus fruit extract
Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus. The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones. Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast...
Experimental
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused …
7-(Carboxyamino)-8-Amino-Nonanoic Acid
Experimental
Zinpentraxin alfa
Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. ... It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With …
Lithium cation
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Description: … displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several ... It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. ... The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily …
Cp-Coeleneterazine
Experimental
Matched Iupac: … cyclopentylmethyl)-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H,3H,7H,8H-imidazo[1,2-a] …
I-Coeleneterazine
Experimental
Matched Iupac: … (2S,8R)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-iodophenyl)methyl]-2H,3H,7H,8H-imidazo[1,2-a] …
cis-Diamminechlorocholylglycinateplatinum(II)
Experimental
Matched Iupac: … platinum(2+) 2-[(1-oxido-4-{4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
Vamotinib
Vamotinib (PF-114) is under investigation in clinical trial NCT02885766 (Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene).
Investigational
Matched Iupac: … 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-(2-{[1,2,4]triazolo[4,3-a] …
ORG-31710
ORG-31710 is a progestational hormone antagonist.
Experimental
Matched Iupac: … -[4-(dimethylamino)phenyl]-5,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,10,11,11a-dodecahydrospiro[cyclopenta[a] …
Matched Description: … ORG-31710 is a progestational hormone antagonist. …
Matched Description: … ORG-31710 is a progestational hormone antagonist. …
Zamerovimab
Investigational
Aspartic Acid-4-Carboxymethyl Ester
Experimental
COTI-2
Investigational
Icaridin
Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Description: … and a member of the piperidine chemical family. ... Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine ... Piperidines are structural components of [piperine], which is a plant extract from the genus _Piper _ …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dodecyldimethylamine N-oxide
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Caprylhydroxamic acid
Experimental
4-Carboxycinnamic Acid
Experimental
TTX-MC138
TTX-MC138 is an antisense oligonucleotide targeting miR-10b. It is under investigation for the treatment of various metastatic cancers.
Investigational
Manitimus
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Investigational
Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]hept-2-en-6-ynamide …
Matched Description: … kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. ... FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Matched Description: … kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. ... FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Ciclonium bromide
Experimental
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Displaying drugs 4776 - 4800 of 11857 in total