Dihydroxyaluminum sodium carbonate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Dihydroxyaluminum sodium carbonate
Accession Number
DB15825
Description
Not Available
Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 143.993
Monoisotopic: 143.9615309
Chemical Formula
CH2AlNaO5
Synonyms
  • Aluminium-natrium-carbonat-dihydroxid
  • Aluminum sodium dihydroxide monocarbonate
  • Dihydroxo-aluminium-natrium-carbonat
  • Dihydroxyaluminum sodium carbonate

Pharmacology

Pharmacology
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Indication
Not Available
Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Medicalerrors
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Chenodeoxycholic acidDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Chenodeoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cholic AcidDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Cholic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dehydrocholic acidDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Dehydrocholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Deoxycholic acidDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Deoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
DolutegravirThe serum concentration of Dolutegravir can be decreased when it is combined with Dihydroxyaluminum sodium carbonate.
HalofantrineDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Halofantrine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Obeticholic acidDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Obeticholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ox bile extractThe serum concentration of Ox bile extract can be decreased when it is combined with Dihydroxyaluminum sodium carbonate.
PhenytoinDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Phenytoin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Taurocholic acidDihydroxyaluminum sodium carbonate can cause a decrease in the absorption of Taurocholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Interactions
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Food Interactions
Not Available

Products

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International/Other Brands
Daxaids / Noacid / Rolaids
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
ทิมมี่Tablet334 mgOralบริษัท บี.เอ็ล.ฮั้ว จำกัด จำกัด1987-02-18Not applicableThailand flag
ทิมมี่Tablet334 mgOralบริษัท บี.เอ็ล.ฮั้ว จำกัด จำกัด1987-02-18Not applicableThailand flag

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
84H8Z9550J
CAS number
16482-55-6
InChI Key
SEIGJEJVIMIXIU-UHFFFAOYSA-J
InChI
InChI=1S/CH2O3.Al.Na.2H2O/c2-1(3)4;;;;/h(H2,2,3,4);;;2*1H2/q;+3;+1;;/p-4
IUPAC Name
sodium dihydroxyalumanylium carbonate
SMILES
[Na+].O[Al+]O.[O-]C([O-])=O

References

General References
Not Available
ChemSpider
7969582
RxNav
23163
ChEMBL
CHEMBL3707202
Wikipedia
Carbaldrate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TabletOral340 mg
TabletOral334 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility269.0 mg/mLALOGPS
logP-0.71ALOGPS
logP0.25ChemAxon
logS0.27ALOGPS
pKa (Strongest Acidic)3.5ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area63.19 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity31.17 m3·mol-1ChemAxon
Polarizability3.52 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on September 11, 2020 17:56 / Updated on February 21, 2021 18:55