Displaying drugs 4851 - 4875 of 10620 in total
Adafosbuvir
Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
Investigational
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2S,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-fluoro-3,4- …
Matched Description: … Impairment on the Pharmacokinetics of AL-335). ... Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal …
Matched Description: … Impairment on the Pharmacokinetics of AL-335). ... Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal …
ASP-3026
ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS.
Investigational
Matched Description: … ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies …
Chymostatin
Experimental
Matched Iupac: … (2S)-2-({[(S)-(2-imino-1,3-diazinan-4-yl)({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl …
Toloxatone
Toloxatone is an antidepressant agent, the first ever use of which was in France, 1984. It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) .
Experimental
Matched Description: … Toloxatone is an antidepressant agent, the first ever use of which was in France, 1984. ... It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) [L1388]. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Ilepatril
Investigational
Harmaline
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Midomafetamine
An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic...
Experimental
Illicit
Investigational
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pazufloxacin
Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …
Ormeloxifene
Ormeloxifene is a third-generation selective estrogen receptor (ER) modulator. In India, ormeloxifene has been marketed since the 1990s as a non-hormonal, non-steroidal oral contraceptive taken once a week, and it was later introduced for the treatment of dysfunctional uterine bleeding. Similar to other selective estrogen receptor modulators (SERMs), ormeloxifene has...
Experimental
Matched Description: … [A251475] The use of levormeloxifene for the treatment of reduced bone turnover and the prevention of ... [A251450,A251465] The use of ormeloxifene for the treatment of perimenopausal bleeding and the management ... of menorrhagia has also been investigated. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Nicomorphine
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Stanolone
A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.
Illicit
Investigational
Matched Description: … A potent androgenic metabolite of testosterone. ... Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Gedatolisib
Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer, Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others.
Investigational
Matched Description: … Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer …
hu3S193
Investigational
PPI-2458
PPI-2458 represents a potentially new and important addition to the growing list of therapeutics aimed at specific molecular oncology targets. PPI-2458 is a novel, proprietary molecule belonging to the fumagillin class of compounds that specifically targets the MetAP-2 enzyme. This class of compounds has been shown to prevent both abnormal...
Investigational
Matched Description: … This class of compounds has been shown to prevent both abnormal cell growth and the formation of new ... of compounds while displaying an improved pharmacokinetic and toxicity profile. ... PPI-2458 represents a potentially new and important addition to the growing list of therapeutics aimed …
Pexelizumab
Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.
Investigational
Faldaprevir
Faldaprevir has been investigated for the treatment of Chronic Hepatitis C.
Investigational
Matched Description: … Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Categories: … Antivirals for treatment of HCV infections …
Iprindole
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Sus scrofa stomach
Experimental
Cinitapride
Cinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.
Investigational
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Blonanserin
Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. It offers improved tolerability as it lacks side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. As a second-generation (atypical) antipsychotic, it is significantly more efficacious in the treatment of the negative symptoms of schizophrenia compared to first-generation...
Investigational
Matched Description: … the negative symptoms of schizophrenia compared to first-generation (typical) antipsychotics. ... a second-generation (atypical) antipsychotic, it is significantly more efficacious in the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Opipramol
Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 4851 - 4875 of 10620 in total