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Displaying drugs 4876 - 4900 of 9744 in total

AVL-3288

Investigational
Matched Synonyms: … (z)-3-(4-chloroanilino)-n-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide …
Matched Iupac: … (2Z)-N-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide …

Chlorfenson

Chlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.
Investigational

2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER

Experimental
Matched Name: … 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER …
Matched Iupac: … ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]-1,3-thiazole-4-carboxylate …

Saccharin

Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.
Investigational
Matched Iupac: … 2,3-dihydro-1lambda6,2-benzothiazole-1,1,3-trione …
Matched Salts cas: … 6155-57-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DULCARYL EFERVESAN TABLET 1/2 DOZ, 100 ADET ... DULCARYL EFERVESAN TABLET 1/2 DOZ, 1000 ADET ... DULCARYL EFERVESAN TABLET 1/2 DOZ, 300 ADET …

Isoindolin-1,3-Dithione

Investigational
Matched Iupac: … 2,3-dihydro-1H-isoindole-1,3-dithione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine

Experimental
Matched Name: … 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine …
Matched Iupac: … 3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2-b]pyridin-1-ol …

1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE

Experimental
Matched Name: … 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …

Pantothenoylaminoethenethiol

Experimental
Matched Synonyms: … 2,4-Dihydroxy-N-[2-(2-mercapto-vinylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide …
Matched Iupac: … (2R)-2,4-dihydroxy-3,3-dimethyl-N-(2-{[(1Z)-2-sulfanylethenyl]carbamoyl}ethyl)butanamide …

Epigallocatechin gallate

Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Investigational
Matched Synonyms: … BENZOIC ACID, 3,4,5-TRIHYDROXY-, (2R,3R)-3,4-DIHYDRO-5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-2H-1-BENZOPYRAN ... -3-YL ESTER ... (-)-Epigallocatechin 3-gallate …
Matched Iupac: … (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

PF-03382792

Pf 03382792 is under investigation in clinical trial NCT01045863 (To Evaluate Safety, Tolerability, Plasma Drug Levels And Other Biological Effects In Healthy Volunteers).
Investigational
Matched Iupac: … 6-fluoro-N-({1-[(4-hydroxyoxan-4-yl)methyl]piperidin-4-yl}methyl)-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indole …

DLO6002

DLO6002 is developed by Summit Corporation and is in phase I of clinical trials for the treatment of Parkinson's disease.
Investigational

S64315

S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).
Investigational

Cu-67 sartate

Investigational

3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid

Experimental
Matched Name: … 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid …
Matched Iupac: … 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid …

5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide

Experimental
Matched Name: … 5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide …
Matched Iupac: … 5-ethoxy-4-{1-methyl-7-oxo-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}thiophene-2-sulfonamide …

Tetrastearoyl cardiolipin

Experimental
Matched Iupac: … [(2R)-2,3-bis(octadecanoyloxy)propoxy][3-({[(2R)-2,3-bis(octadecanoyloxy)propoxy](hydroxy)phosphoryl} ... oxy)-2-hydroxypropoxy]phosphinic acid …

{4-[(2S)-2-({[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}amino)-3-oxo-3-(pentylamino)propyl]phenoxy}malonic acid

Experimental
Matched Name: … {4-[(2S)-2-({[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}amino)-3-oxo-3-(pentylamino)propyl]phenoxy}malonic …
Matched Iupac: … 2-{4-[(2S)-2-({[(1S)-1-carboxy-2-phenylethyl]carbamoyl}amino)-2-(pentylcarbamoyl)ethyl]phenoxy}propanedioic …

HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM

Experimental
Matched Name: … HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM …
Matched Iupac: … (2Z)-N-(3-nitrophenyl)-4-{3-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}-2,5-dihydropyrimidin-2-imine …

Simtuzumab

Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational

2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3-oxopropyl]phenyl}(carboxycarbonyl)amino]benzoic acid

Experimental
Matched Name: … 2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3- …
Matched Iupac: … 2-(1-carboxy-N-{4-[(2S)-2-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}carbamoyl)-2-{[(prop-2-en-1 …

Bioymifi

Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi is currently being investigated as an anti-tumor agent.[A257048,A257053]
Investigational
Matched Synonyms: … 5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione ... 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3- …
Matched Iupac: … 6-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-hydroxy-1H-isoindol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tideglusib

Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia...
Investigational
Withdrawn
Matched Synonyms: … 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE ... 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … (GSK-3). ... anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 …
Matched Categories: … Glycogen Synthase Kinase 3, antagonists & inhibitors …

JNJ-1802

Investigational
Matched Synonyms: … (+)-(2s)-2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy ... 2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol ... Ethanone, 2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy …
Matched Iupac: … (2S)-2-(4-chloro-2-methoxyphenyl)-2-[(3-methanesulfonyl-5-methoxyphenyl)amino]-1-[5-(trifluoromethoxy ... )-1H-indol-3-yl]ethan-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Seladelpar

Seladelpar (MBX-8025) has been used in trials studying the treatment of Hyperlipidemia.
Investigational
Matched Iupac: … 2-(4-{[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl}-2-methylphenoxy)acetic acid …
Matched Salts cas: … 928821-40-3 …

4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline

Experimental
Matched Name: … 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline …
Matched Iupac: … 4-bromo-2-[(3R,5S)-3,5-dimethylpiperidine-1-carbonyl]aniline …
Displaying drugs 4876 - 4900 of 9744 in total