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Displaying drugs 4876 - 4900 of 10619 in total
Cefminox
Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
Experimental
Ritanserin
Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
Investigational
Matched Description: … Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Azimilide
Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.
Investigational
Matched Description: … Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of …
GS-6620
GS-6620 is under investigation in clinical trial NCT01316237 (A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naïve Subjects With Chronic Hepatitis C Virus Infection).
Investigational
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-4-hydroxy …
Matched Description: … trial NCT01316237 (A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of …
Matched Description: … trial NCT01316237 (A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of …
Silk sericin
Experimental
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Iupac: … (1'R,3R,10'S)-5-(2,2,2-trifluoroethyl)-5'-[(1E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-en-1-yl]spiro …
Matched Description: … It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682] …
Matched Description: … It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682] …
N-Alkyl dimethyl benzyl ammonium chloride (C12-C18)
Experimental
Matched Mixtures name: … SINBIO Sanitizer S-300 …
BNT162b1 SARS-CoV-2 Vaccine
BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin...
Investigational
Matched Description: … the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin ... either 10 or 30μg of BNT162b1, with further improvements following a second dose. ... BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a …
Furazolidone
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Experimental
Vet approved
Matched Description: … Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Ketobemidone
Ketobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or...
Investigational
Matched Description: … to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection. ... This makes it useful for some types of pain that don't respond well to other opioids. ... The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Imexon
Imexon is currently being studied for the treatment of pancreatic, lung, breast, prostate, melanoma, and multiple myeloma cancers. It belongs to the family of drugs called cyanoaziridine derivatives. Also called Amplimexon. Imexon is a cyanoaziridine derivative.
Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane...
Investigational
Matched Description: … It belongs to the family of drugs called cyanoaziridine derivatives. Also called Amplimexon. ... Imexon is currently being studied for the treatment of pancreatic, lung, breast, prostate, melanoma, ... Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane potential …
Milademetan
Milademetan is under investigation in clinical trial NCT02319369 (Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)).
Investigational
Matched Iupac: … (3'R,4'S,5'R)-N-[(3R,6S)-6-carbamoyloxan-3-yl]-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl …
Matched Description: … Milademetan is under investigation in clinical trial NCT02319369 (Safety, Tolerability and Pharmacokinetics of …
Matched Description: … Milademetan is under investigation in clinical trial NCT02319369 (Safety, Tolerability and Pharmacokinetics of …
Oxidized coenzyme A
Experimental
Ceftiofur
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Dextromethadone
Dextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).
Investigational
Matched Description: … Dextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients …
SARS-CoV-2 Sclamp
The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp. The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in...
Investigational
Matched Description: … The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations ... Preclinical trials showed the vaccine candidate produced high levels of neutralizing antibodies, and ... As of July 13, 2020, the candidate is being tested for safety and immunogenicity in Phase 1 clinical …
Samarium Sm-153
Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer, Prostate Cancer, and Metastatic Cancer.
Investigational
Matched Description: … Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer …
3-thiaoctanoyl-CoA
Experimental
Methacrylyl-Coenzyme A
Experimental
Shigella sonnei strain 53G
Investigational
NKG2D-ACE2 CAR-NK Cell
These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. Chimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling...
Investigational
Matched Description: … The ACE2 is a receptor for SARS-Cov-2, binding to the S-protein of the viral envelope and competitively ... inhibiting SARS-Cov-2 infection of type II alveolar epithelial cells. ... as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of …
Lysergic acid diethylamide
Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD...
Illicit
Investigational
Withdrawn
Matched Description: … of LSD on brain chemistry, and varies according to the susceptibility of the individual to the disorder ... state reminiscent of post-traumatic stress disorder. ... Debate continues over the nature and causes of chronic flashbacks. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Indalpine
Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market.
Investigational
Withdrawn
Matched Description: … Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. ... However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 4876 - 4900 of 10619 in total