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Displaying drugs 4901 - 4925 of 10619 in total

Pirlindole

This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug. Pirlindole is a...
Experimental
Matched Description: … supported by many years of clinical experience in the treatment of depression. ... Pirlindole's efficacy and safety have also been shown in the treatment of fibromyalgia. ... This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

SGN-1

SGN-1 is a genetically modified strain of Salmonella enterica comprising methioninase.
Investigational
Matched Description: … SGN-1 is a genetically modified strain of _Salmonella enterica_ comprising methioninase. …

Polaprezinc

Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. It was determined that polaprezinc may be effective in pressure ulcer treatment . A study in 2013 showed...
Experimental
Matched Description: … Polaprezinc is a chelated form of zinc and L-carnosine. ... A study in 2013 showed that CO-administration of polaprezinc may be effective against small intestine …

SN-38

7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan DB00762, a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative...
Investigational
Matched Description: … 7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan ... [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. ... SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung …

ST-36

ST-36 is a cell-penetrating dominant-negative form of activating transcription factor 5. In 2017, it received orphan drug designation by the FDA for the treatment of glioma.
Investigational
Matched Description: … ST-36 is a cell-penetrating dominant-negative form of activating transcription factor 5. ... In 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341] …

5-Mercaptoethanol-2-decenoyl-coenzyme A

Experimental

L-serine O-sulfate

Experimental

SP-876

Experimental

Sp-722

Experimental

SGN-15

SGN-15 is studied in the treatment of cancer. It combines a monoclonal antibody with the anticancer drug doxorubicin. Monoclonal antibodies are substances that are made in the laboratory and that can locate and bind to cancer cells. Doxorubicin is a type of anthracycline antitumor antibiotic. When it is combined with...
Investigational
Matched Description: … SGN-15 is studied in the treatment of cancer. ... Doxorubicin is a type of anthracycline antitumor antibiotic. ... When it is combined with a monoclonal antibody, it forms a type of drug conjugate. …

SC-236

SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
Experimental
Investigational
Matched Description: … SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been …

STF-31

Experimental

SM-337

Investigational

SEL-24

Investigational

ST-003

ST-003 is a novel galanin receptor inhibitor being investigated for the treatment of primary sclerosing cholangitis.
Investigational
Matched Description: … ST-003 is a novel galanin receptor inhibitor being investigated for the treatment of primary sclerosing …

Ephedra sinica stem

Experimental

Iproniazid

Withdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine.
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dapoxetine

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation...
Investigational
Matched Description: … Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. ... Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation in December ... In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tianeptine

Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants . Tianeptine was discovered and...
Investigational
Matched Description: … in the treatment of irritable bowel syndrome (IBS) [A31983]. ... Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

SO-101

SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.
Investigational
Matched Description: … SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected ... Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages …

ST-101

ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …

SQ-109

SQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen.
Investigational
Matched Description: … SQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. …

SJ-733

SJ-733 has been used in trials studying Malaria.
Investigational

V-SARS

COVID-19 convalescent plasma is currently being acquired from recovered COVID-19 patients and used as prophylaxis for the virus. This therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, and packages it into a once-daily pill form. Immunitor Inc., the sponsor, is currently testing this oral...
Investigational
Matched Description: … This therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, …

SP-420

SP-420 is under investigation in clinical trial NCT03801889 (SP-420 in Subjects With Transfusion-dependent Beta-thalassemia or Other Rare Anemias).
Investigational
Displaying drugs 4901 - 4925 of 10619 in total