Displaying drugs 26 - 50 of 245 in total
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid ... N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Eteplirsen
Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory...
Approved
Investigational
Matched Synonyms: … ),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl)-1-piperazinyl)-N,N-dimethylphosphonamidate ... (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G …
Matched Description: … and RNA. ... of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA ... Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … and RNA. ... of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA ... Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Nucleic Acids, Nucleotides, and Nucleosides …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … gyrase, halting DNA replication. ... fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … gyrase, halting DNA replication. ... fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Olaparib
Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health …
Matched Categories: … MATE 2-K Inhibitors ... Antineoplastic and Immunomodulating Agents ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health …
Matched Categories: … MATE 2-K Inhibitors ... Antineoplastic and Immunomodulating Agents ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Trifluridine
Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to idoxuridine . It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. It displays effective antiviral activity against Herpes simplex virus type 1...
Approved
Investigational
Matched Synonyms: … 5-Trifluoromethyl-2-deoxyuridine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine …
Matched Description: … It displays effective antiviral activity against Herpes simplex virus type 1 and 2 [A35271]. ... of cancer cells following cell uptake to aberrate DNA function during cell replication [F649]. ... , trifluridine acts as a thymidine-based nucleoside metabolic inhibitor that gets incorporated into DNA …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … THILO %1 GÖZ DAMLASI, 5 ML …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine …
Matched Description: … It displays effective antiviral activity against Herpes simplex virus type 1 and 2 [A35271]. ... of cancer cells following cell uptake to aberrate DNA function during cell replication [F649]. ... , trifluridine acts as a thymidine-based nucleoside metabolic inhibitor that gets incorporated into DNA …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … THILO %1 GÖZ DAMLASI, 5 ML …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) ... Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … INTRON-A 10 MIU/1 ML ENJEKTABL ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) ... Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … INTRON-A 10 MIU/1 ML ENJEKTABL ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA ... which encodes for the human protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA ... which encodes for the human protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Selenium Sulfide
Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Selsun Blue 2-in-1 ... Selsun Blue, 2-IN-1 ... Head and Shoulders Itch …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Selsun Blue 2-in-1 ... Selsun Blue, 2-IN-1 ... Head and Shoulders Itch …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Description: … the unique mechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and ... the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and ... re-approval' of tegaserod for treatment of IBS-C specifically in female patients less than 65 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 2-Ring …
Matched Description: … the unique mechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and ... the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and ... re-approval' of tegaserod for treatment of IBS-C specifically in female patients less than 65 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 2-Ring …
Letermovir
Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Iupac: … 2-[(4S)-8-fluoro-3-[2-methoxy-5-(trifluoromethyl)phenyl]-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3,4-dihydroquinazolin …
Matched Description: … [A31290] Letermovir has recieved both priority and orphan drug status from the FDA. ... [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... DNA Terminase Complex Inhibitors ... Cytomegalovirus DNA Terminase Complex Inhibitor …
Matched Products: … PREVYMİS 240 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... PREVYMİS 480 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Matched Description: … [A31290] Letermovir has recieved both priority and orphan drug status from the FDA. ... [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... DNA Terminase Complex Inhibitors ... Cytomegalovirus DNA Terminase Complex Inhibitor …
Matched Products: … PREVYMİS 240 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... PREVYMİS 480 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Voretigene neparvovec
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy. An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can...
Approved
Matched Description: … virus is the high predictability, unlike retrovirus, as they associate with a specific region of the human ... It is not pathogenic and it causes a very mild immune response. ... [L1094] An adeno-associated virus is a small virus that infects humans and other primates. …
Insulin degludec
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and Type 2 Diabetes. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... TRESIBA FLEXTOUCH 100 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... TRESIBA FLEXTOUCH 100 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Anthralin
Anthralin (1,8‐dihydroxy‐9anthrone, dithranol) is an older anti-psoriatic agent that was first synthesized as a derivative of chrysarobin, obtained from the araroba tree in Brazil over 100 years ago. Adverse effects of anthralin include irritation and discoloration of the skin .
This specific property of the molecule inspired workers to study...
Approved
Matched Description: … its penetration and efficacy [L1979]. ... Adverse effects of anthralin include irritation and discoloration of the skin [A27277]. ... Various formulations of the drug are available, including solutions, foams, and shampoos [L1979]. …
Matched Products: … Anthraforte 2 Ointment 2% ... Anthraforte 1 Ointment 1% …
Matched Products: … Anthraforte 2 Ointment 2% ... Anthraforte 1 Ointment 1% …
Arsenic trioxide
Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LEUSENOX 2 MG/ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 10 ADET ... อะซาดิน 1 มก. / มล. ... TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADET …
Matched Products: … LEUSENOX 2 MG/ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 10 ADET ... อะซาดิน 1 มก. / มล. ... TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADET …
Pitavastatin
Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Iupac: … (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. ... lipid levels and ultimately reduce the risk of cardiovascular disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Trolise 1 mg Filmtabletten ... PITAMIN 1 MG EFERVESAN TABLET, 30 ADET ... PITAMIN 1 MG EFERVESAN TABLET, 90 ADET …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. ... lipid levels and ultimately reduce the risk of cardiovascular disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Trolise 1 mg Filmtabletten ... PITAMIN 1 MG EFERVESAN TABLET, 30 ADET ... PITAMIN 1 MG EFERVESAN TABLET, 90 ADET …
Etravirine
Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of...
Approved
Matched Iupac: … 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile …
Matched Description: … virus type 1 (HIV-1), and consequently blocks DNA-dependent and RNA-dependent polymerase activity. ... Etravirine does not inhibit human DNA polymerase alpha, beta or gamma. ... Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Matched Description: … virus type 1 (HIV-1), and consequently blocks DNA-dependent and RNA-dependent polymerase activity. ... Etravirine does not inhibit human DNA polymerase alpha, beta or gamma. ... Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Insulin glargine
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and Type 2 Diabetes. ... [L34964]
Insulin glargine is produced by recombinant DNA technology using a non-pathogenic laboratory ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LANTUS 100 IU/ML SUBKUTAN KULLANIM İÇİN ENJEKSİYONLUK SOLÜSYON, 1 ADET ... BASAGLAR KWIKPEN 100 U/ML SC KULLANIM ICIN ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LANTUS 100 IU/ML SUBKUTAN KULLANIM İÇİN ENJEKSİYONLUK SOLÜSYON, 1 ADET ... BASAGLAR KWIKPEN 100 U/ML SC KULLANIM ICIN ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET …
Mometasone furoate
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Iupac: … 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl furan-2-carboxylate ... (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-1-(2-chloroacetyl)-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … M-FURO MANT % 0.1 + % 1 KREM, 20G ... M-FURO FA %0.1 + %2 KREM, 30 G ... MATEC 2/200 MCG INHALASYON TOZ IÇEREN KAPSÜL , 60 KAPSÜL …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … M-FURO MANT % 0.1 + % 1 KREM, 20G ... M-FURO FA %0.1 + %2 KREM, 30 G ... MATEC 2/200 MCG INHALASYON TOZ IÇEREN KAPSÜL , 60 KAPSÜL …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …
Ozenoxacin
To date, ozenoxacin has been used in trials studying the treatment of impetigo.
As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by Staphylococccus aureus or Streptococcus pyogenes in adult and pediatric patients...
Approved
Investigational
Matched Iupac: … 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic …
Matched Description: … *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age ... s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by ... and older. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age ... s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by ... and older. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Dupilumab
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin ... [A180478] Dupilumab was generated by recombinant DNA technology in Chinese Hamster Ovary cell suspension ... under investigations for potential therapeutic use in diseases driven by allergic reactions or type 2 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET ... Dupixent 175 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET ... Dupixent 175 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 1 ADET …
Pozelimab
CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US. The pathophysiology of this disease is mainly attributed to the deficiency of the CD55 protein, which is the main regulator of the complement...
Approved
Investigational
Matched Description: … [A261120]
Pozelimab is a human, monoclonal immunoglobulin G4P antibody against the terminal ... cleavage of C3 and C5 respectively into immunoreactive peptides C3a and C5a. ... Under normal circumstances, CD55 inhibits the activity of C3 and C5 convertases, thus preventing the …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Salts cas: … 63585-09-1 …
Matched Categories: … Pyrophosphate Analog DNA Polymerase Inhibitor …
Matched Salts cas: … 63585-09-1 …
Matched Categories: … Pyrophosphate Analog DNA Polymerase Inhibitor …
Doravirine
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Iupac: … 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2 …
Matched Description: … treatments available for the management of HIV-1 infection. ... no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic ... Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine, tenofovir disoproxil and doravirine ... Heterocyclic Compounds, 1-Ring …
Matched Description: … treatments available for the management of HIV-1 infection. ... no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic ... Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine, tenofovir disoproxil and doravirine ... Heterocyclic Compounds, 1-Ring …
Beclomethasone dipropionate
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Synonyms: … (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione …
Matched Iupac: … 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H ... ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... formoterol, glycopyrronium bromide and beclometasone …
Matched Products: … RİNOMİL 100 MCG BURUN SPREYİ, SÜSPANSİYON, 1 ŞİŞE …
Matched Iupac: … 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H ... ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... formoterol, glycopyrronium bromide and beclometasone …
Matched Products: … RİNOMİL 100 MCG BURUN SPREYİ, SÜSPANSİYON, 1 ŞİŞE …
Fidanacogene elaparvovec
Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B. Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to...
Approved
Investigational
Matched Description: … abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to be 1 ... Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human ... 2–3 times a week for severe hemophilia, although this carries a significant financial burden to the …
Displaying drugs 26 - 50 of 245 in total