Displaying drugs 476 - 500 of 2637 in total
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
Simenepag isopropyl
Simenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Investigational
Matched Synonyms: … Simenepag isopropyl …
Matched Name: … Simenepag isopropyl …
Matched Description: … Simenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma …
Matched Name: … Simenepag isopropyl …
Matched Description: … Simenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma …
Aganepag isopropyl
Aganepag isopropyl is under investigation in clinical trial NCT01110499 (Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension).
Investigational
Matched Synonyms: … Aganepag isopropyl …
Matched Name: … Aganepag isopropyl …
Matched Description: … Aganepag isopropyl is under investigation in clinical trial NCT01110499 (Safety and Efficacy of AGN-210961 …
Matched Name: … Aganepag isopropyl …
Matched Description: … Aganepag isopropyl is under investigation in clinical trial NCT01110499 (Safety and Efficacy of AGN-210961 …
Aprobarbital
Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment indicated for the use of aprobarbital was subsequently insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives...
Experimental
Illicit
Matched Synonyms: … 5-isopropyl-5-allylbarbituric acid ... 5-allyl-5-isopropylbarbituric acid …
Matched Description: … It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant ... Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant ... Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and …
Matched Categories: … Hypnotics and Sedatives …
Mucor circinelloides f. lusitanicus
Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …
STRO-001
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …
Phytic acid
Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Acido fitico ... Fytic acid ... Acide fytique …
Matched Name: … Phytic acid …
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Matched Categories: … Alcohols ... Sugar Alcohols …
Matched Name: … Phytic acid …
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Matched Categories: … Alcohols ... Sugar Alcohols …
Heptanoic acid
Experimental
Investigational
Matched Synonyms: … Enanthic acid ... Heptoic acid ... Enanthylic acid …
Matched Name: … Heptanoic acid …
Matched Iupac: … heptanoic acid …
Matched Name: … Heptanoic acid …
Matched Iupac: … heptanoic acid …
Turofexorate isopropyl
Fxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).
Investigational
Matched Synonyms: … Turofexorate isopropyl …
Matched Name: … Turofexorate isopropyl …
Matched Description: … Fxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl …
Matched Name: … Turofexorate isopropyl …
Matched Description: … Fxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl …
6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL
Experimental
Matched Name: … 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL …
Matched Iupac: … 6-benzyl-1-[(benzyloxy)methyl]-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-benzyl-1-[(benzyloxy)methyl]-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Fenofibrate
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591]
Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Synonyms: … 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester ... Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate ... Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Mixtures name: … ACIDO FENOFIBRICO / ROSUVASTATINA 135 MG/10 MG …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate ... Acids, Acyclic …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Mixtures name: … ACIDO FENOFIBRICO / ROSUVASTATINA 135 MG/10 MG …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate ... Acids, Acyclic …
Nimodipine
Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Synonyms: … 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ... isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate ... isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate …
Matched Description: … of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Nicotinic Acids …
Matched Description: … of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Nicotinic Acids …
Phenoxyethanol
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Synonyms: … 2-Phenoxyethyl alcohol …
Matched Description: … Phenoxyethanol is an ether alcohol with aromatic properties. ... It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. ... It has also been used in vaccines and shown to inactivate bacteria, and several types of yeast [A32838 …
Matched Mixtures name: … Alcohol wipes ... 75% Alcohol Wipes ... Aiweier Alcohol Wipes …
Matched Categories: … Alcohols …
Matched Description: … Phenoxyethanol is an ether alcohol with aromatic properties. ... It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. ... It has also been used in vaccines and shown to inactivate bacteria, and several types of yeast [A32838 …
Matched Mixtures name: … Alcohol wipes ... 75% Alcohol Wipes ... Aiweier Alcohol Wipes …
Matched Categories: … Alcohols …
Tricarballylic acid
Experimental
Matched Synonyms: … Carballylic acid ... 3-carboxyglutaric acid ... β-carboxyglutaric acid …
Matched Name: … Tricarballylic acid …
Matched Iupac: … propane-1,2,3-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Tricarballylic acid …
Matched Iupac: … propane-1,2,3-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Titanium dioxide
Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Description: … It is typically extracted from ilmenite, rutile and anatase. …
Matched Mixtures name: … Hyaluronic Acid Watery Sun ... TANRI Sunscreen SPF15 ... TANRI Sunscreen SPF30 …
Matched Categories: … Astringents and Deodorants …
Matched Products: … Quick and Clean Oil Free Sun Spf35 Pa ... Im Safe for Baby and Silver ... Peaufinee Baby and Kids Sun …
Matched Mixtures name: … Hyaluronic Acid Watery Sun ... TANRI Sunscreen SPF15 ... TANRI Sunscreen SPF30 …
Matched Categories: … Astringents and Deodorants …
Matched Products: … Quick and Clean Oil Free Sun Spf35 Pa ... Im Safe for Baby and Silver ... Peaufinee Baby and Kids Sun …
Demplatin pegraglumer
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Benzylpenicillin
Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms.
Natural penicillins are considered...
Approved
Vet approved
Matched Synonyms: … Benzyl benicillin ... Benzylpenicillinic acid ... 6-(2-phenylacetamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Resistance patterns, susceptibility and treatment guidelines vary across regions. ... by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and ... G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Resistance patterns, susceptibility and treatment guidelines vary across regions. ... by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and ... G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase …
Acrylic Acid
A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.
Experimental
Matched Synonyms: … acroleic acid ... 2-Propenoic acid ... Propenoic acid …
Matched Name: … Acrylic Acid …
Matched Iupac: … prop-2-enoic acid …
Matched Description: … A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group. …
Matched Categories: … Equipment and Supplies ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Acrylic Acid …
Matched Iupac: … prop-2-enoic acid …
Matched Description: … A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group. …
Matched Categories: … Equipment and Supplies ... Acids, Acyclic ... Carboxylic Acids …
Palmitic Acid
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … 1-hexyldecanoic acid ... Hexadecoic acid ... Palmitic Acid …
Matched Name: … Palmitic Acid …
Matched Iupac: … hexadecanoic acid …
Matched Description: … A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. …
Matched Salts name: … 16-chloropalmitic acid …
Matched Categories: … Fatty Acids ... Palmitic Acids …
Matched Name: … Palmitic Acid …
Matched Iupac: … hexadecanoic acid …
Matched Description: … A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. …
Matched Salts name: … 16-chloropalmitic acid …
Matched Categories: … Fatty Acids ... Palmitic Acids …
Ethanesulfonic acid
Experimental
Matched Synonyms: … 1-ethanesulfonic acid ... 2-ethanesulfonic acid ... Ethylsulfonic acid …
Matched Name: … Ethanesulfonic acid …
Matched Iupac: … ethanesulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Matched Name: … Ethanesulfonic acid …
Matched Iupac: … ethanesulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Fenoterol
Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Approved
Investigational
Matched Synonyms: … 3,5-dihydroxy-α-(((p-hydroxy-α-methylphenethyl)amino)methyl)benzyl alcohol …
Matched Description: … Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic. …
Matched Categories: … Alcohols ... Amino Alcohols ... fenoterol and ipratropium bromide ... Genito Urinary System and Sex Hormones …
Matched Description: … Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic. …
Matched Categories: … Alcohols ... Amino Alcohols ... fenoterol and ipratropium bromide ... Genito Urinary System and Sex Hormones …
PTX-100
Investigational
Matched Synonyms: … acid ... 2-{[2-benzyl-4-(5-methyl-3H-imidazol-4-ylmethyl)-3-oxo-piperazine-1-carbonyl]- amino}-4methyl-pentanoic …
Matched Iupac: … acid ... (2S)-2-{[(2S)-2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic …
Matched Iupac: … acid ... (2S)-2-{[(2S)-2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic …
5-phenylpentanoic acid
Experimental
Matched Synonyms: … 5-Phenylvaleric acid ... Phenylvaleric acid ... Benzenepentanoic-acid …
Matched Name: … 5-phenylpentanoic acid …
Matched Iupac: … 5-phenylpentanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … 5-phenylpentanoic acid …
Matched Iupac: … 5-phenylpentanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid
Experimental
Matched Name: … 2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid …
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid …
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid …
Displaying drugs 476 - 500 of 2637 in total