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Displaying drugs 5126 - 5150 of 10619 in total
Experimental
Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents.
Experimental
Matched Description: … Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase …
Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density).
Investigational
Matched Description: … Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density). ... Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing …
SEphB4-HSA is under investigation in clinical trial NCT02495896 (Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors).
Investigational
Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver).
Investigational
Matched Description: … Recurrence in Patients With Ascites Due to Cirrhosis of the Liver). ... Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites …
Selatogrel is under investigation in clinical trial NCT03814200 (A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects).
Investigational
Matched Description: … Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects). ... Selatogrel is under investigation in clinical trial NCT03814200 (A Study to Investigate the Effect of
Investigational
Experimental
Investigational
Experimental
Investigational
Vet approved
Matched Iupac: … (2R,3S,4R,6S)-6-[(3aR,4R,4'R,5'S,6S,6'R,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-[(2R,3aS,3'aR ... ,6'R,7R,7'S,7aR,7'aR)-7'-acetyl-6'-methyl-7-[(2-methylpropanoyl)oxy]-octahydro-2'H,3aH-2,4'-spirobi[[ …
Investigational
Experimental
Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
Experimental
Vet approved
Matched Iupac: … (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl …
Experimental
Experimental
SF1126 is an integrin-targeted PI3 kinase inhibitor.
Investigational
MYO-029 is a human anti-GDF-8 monoclonal antibody, which is being developed to treat muscle-wasting diseases including muscular dystrophy and age-related sarcopenia.
Investigational
Investigational
Investigational
According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) and when delivered following incorporation into an E1B-deleted adenovirus (Ad/L523S)." It has been investigated as a lung cancer vaccine.
Investigational
Serdemetan has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Description: … Serdemetan has been used in trials studying the treatment of Neoplasms. …
Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Description: … Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast ... Epothilones are 16-member ring macrolides with antimicrotubule activity that share a similar mechanism of ... synthetic epothilone and is the first such compound to be in clinical development to combat several forms of
Displaying drugs 5126 - 5150 of 10619 in total