Displaying drugs 5176 - 5200 of 5863 in total
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo- ... (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy …
Matched Iupac: … (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Matched Products: … เตตระไลซอล 300 ... CycloPel 300 mg Kapseln ... TETRALYSAL® CAPSULAS 300 MG …
Matched Iupac: … (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Matched Products: … เตตระไลซอล 300 ... CycloPel 300 mg Kapseln ... TETRALYSAL® CAPSULAS 300 MG …
Iopofosine I-131
Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).
Investigational
Matched Synonyms: … 2-((HYDROXY((18-(4-(131I)IODOPHENYL)OCTADECYL)OXY)PHOSPHINYL)OXY)-N,N,NTRIMETHYLETHANAMINIUM INNER SALT ... Ethanaminium, 2-((hydroxy((18-(4-(iodo-131I)phenyl)octadecyl)oxy)phosphinyl)oxy)-N,N,N-trimethyl-, inner …
Matched Iupac: … 18-[4-(¹³¹I)iodophenyl]octadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Description: … Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation …
Matched Iupac: … 18-[4-(¹³¹I)iodophenyl]octadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Description: … Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation …
S-oxy-L-cysteine
Experimental
Matched Synonyms: … 3-(oxidosulfanyl)-L-alanine …
Matched Iupac: … (2R)-2-amino-3-sulfinylpropanoic acid …
Matched Iupac: … (2R)-2-amino-3-sulfinylpropanoic acid …
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … -c)pyrrol-2(1h)-yl)-3-hydroxy-2-phenyl-, (2s)- ... 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) ... -3-hydroxy-2-phenylpropan-1-one …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) ... -3-hydroxy-2-phenylpropan-1-one …
Etodolac
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid ... 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid …
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid …
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Mixtures name: … NuDroxiPAK E-400 ... ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET ... S-ETODUO 150/300 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … ETODOLACO TABLETAS POR 300 MG ... EDOLAR FORT 400 MG FİLM KAPLI TABLET, 30 ADET ... DOLELAC FORT 400 MG FİLM KAPLI TABLET, 30 ADET …
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid …
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Mixtures name: … NuDroxiPAK E-400 ... ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET ... S-ETODUO 150/300 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … ETODOLACO TABLETAS POR 300 MG ... EDOLAR FORT 400 MG FİLM KAPLI TABLET, 30 ADET ... DOLELAC FORT 400 MG FİLM KAPLI TABLET, 30 ADET …
5-(Hydroxy-Methyl-Amino)-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Experimental
Matched Name: … 5-(Hydroxy-Methyl-Amino)-3-Methyl-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5R)-5-[hydroxy(methyl)amino]-3-methylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R,3R,5R)-5-[hydroxy(methyl)amino]-3-methylpyrrolidine-2-carboxylic acid …
3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene
Experimental
Matched Name: … 3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene …
Matched Iupac: … benzyl N-[(1S)-2-phenyl-1-{[(3S)-1-phenyl-5-phenylmethanesulfonylpentan-3-yl]carbamoyl}ethyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-2-phenyl-1-{[(3S)-1-phenyl-5-phenylmethanesulfonylpentan-3-yl]carbamoyl}ethyl]carbamate …
5-(3-Amino-4,4-Dihyroxy-Butylsulfanylmethyl)-Tetrahydro-Furan-2,3,4-Triol
Experimental
Matched Name: … 5-(3-Amino-4,4-Dihyroxy-Butylsulfanylmethyl)-Tetrahydro-Furan-2,3,4-Triol …
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid …
3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside
Experimental
Matched Name: … 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside …
Matched Iupac: … (2R,3R,4S,5R,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-3,5-dihydroxy ... -6-(hydroxymethyl)oxan-4-yl octanoate …
Matched Iupac: … (2R,3R,4S,5R,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-3,5-dihydroxy ... -6-(hydroxymethyl)oxan-4-yl octanoate …
2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid
Experimental
Matched Name: … 2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid …
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid …
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid …
1,2-Di-1-(3,7,11,15-Tetramethyl-Hexadecane)-Sn-Glycero-3-Phosphate
Experimental
Matched Name: … 1,2-Di-1-(3,7,11,15-Tetramethyl-Hexadecane)-Sn-Glycero-3-Phosphate …
Matched Iupac: … [(2S)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propoxy]phosphonic acid …
Matched Iupac: … [(2S)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propoxy]phosphonic acid …
1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID
Experimental
Matched Name: … 1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID …
Matched Iupac: … (1S,3R,4R,5S)-1,3,4-trihydroxy-5-(3-phenoxypropyl)cyclohexane-1-carboxylic acid …
Matched Iupac: … (1S,3R,4R,5S)-1,3,4-trihydroxy-5-(3-phenoxypropyl)cyclohexane-1-carboxylic acid …
3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid
Experimental
Matched Name: … 3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid …
Matched Iupac: … 3-{[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]oxy}propanoic acid …
Matched Iupac: … 3-{[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]oxy}propanoic acid …
(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID
Experimental
Matched Name: … (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID …
Matched Iupac: … 2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}phenoxy)acetic acid …
Matched Iupac: … 2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}phenoxy)acetic acid …
(3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE
Experimental
Matched Name: … (3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide …
Matched Iupac: … (3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide …
1-{[N-(1-Imino-guanidino-methyl)]sulfanylmethyl}-3-trifluoromethyl-benzene
Experimental
Matched Name: … 1-{[N-(1-Imino-guanidino-methyl)]sulfanylmethyl}-3-trifluoromethyl-benzene …
Matched Iupac: … N-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine …
Matched Iupac: … N-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine …
3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one
Experimental
Matched Name: … 3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one …
Matched Iupac: … 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one …
Matched Iupac: … 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one …
5-bromo-3-(pyrrolidin-1-ylsulfonyl)-1H-indole-2-carboxamide
Experimental
Matched Name: … 5-bromo-3-(pyrrolidin-1-ylsulfonyl)-1H-indole-2-carboxamide …
Matched Iupac: … 5-bromo-3-(pyrrolidine-1-sulfonyl)-1H-indole-2-carboxamide …
Matched Iupac: … 5-bromo-3-(pyrrolidine-1-sulfonyl)-1H-indole-2-carboxamide …
1-(c14-c18 esteroyl)-2-docosahexanoyl-sn-glycero-3-phosphocholine
Experimental
Matched Name: … 1-(c14-c18 esteroyl)-2-docosahexanoyl-sn-glycero-3-phosphocholine …
[4-R-(4-ALPHA,6-BETA,7-BETA]-HEXAHYDRO-5,6-DI(HYDROXY)-1,3-DI(ALLYL)-4,7-BISPHENYLMETHYL)-2H-1,3-DIAZEPINONE
Experimental
Matched Name: … [4-R-(4-ALPHA,6-BETA,7-BETA]-HEXAHYDRO-5,6-DI(HYDROXY)-1,3-DI(ALLYL)-4,7-BISPHENYLMETHYL)-2H-1,3-DIAZEPINONE …
Matched Iupac: … (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(prop-2-en-1-yl)-1,3-diazepan-2-one …
Matched Iupac: … (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(prop-2-en-1-yl)-1,3-diazepan-2-one …
2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide
Experimental
Matched Name: … 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole …
Matched Iupac: … 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,3-thiazole-5 …
Matched Iupac: … 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,3-thiazole-5 …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... damage) during trials, and to discontinue its distribution in countries where the drug had been approved ... AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver …
Matched Categories: … Blood and Blood Forming Organs ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... damage) during trials, and to discontinue its distribution in countries where the drug had been approved ... AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver …
Matched Categories: … Blood and Blood Forming Organs ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Sanfetrinem cilexetil
Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil).
Investigational
Matched Synonyms: … 5s,8as,8br)-1,2,5,6,7,8,8a,8b-octahydro-1-((r)-1-hydroxyethyl)-5-methoxy-2-oxoazeto(2,1-a)isoindole-4- …
Matched Description: … Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability …
Matched Description: … Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability …
Rosiglitazone
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Synonyms: … (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
Matched Description: … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … Avandia 4mg ... AVANDIA TABLET 4MG …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
Matched Description: … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … Avandia 4mg ... AVANDIA TABLET 4MG …
Vigabatrin
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid …
Matched Iupac: … 4-aminohex-5-enoic acid …
Matched Description: … inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was ... [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its …
Matched Categories: … Cytochrome P-450 CYP2C9 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2C9 Inducers (strength unknown) …
Matched Products: … Sabril Pwr 3g/sachet …
Matched Iupac: … 4-aminohex-5-enoic acid …
Matched Description: … inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was ... [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its …
Matched Categories: … Cytochrome P-450 CYP2C9 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2C9 Inducers (strength unknown) …
Matched Products: … Sabril Pwr 3g/sachet …
Displaying drugs 5176 - 5200 of 5863 in total