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Displaying drugs 501 - 525 of 1393 in total

Aripiprazole

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational

Avanafil

Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved

Edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved

Afatinib

Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved

Neratinib

Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Approved
Investigational

Indomethacin

Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational

Delafloxacin

Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, among others. It was approved in June 2017 under the trade name Baxdela for use in the treatment of...
Approved
Investigational

Lusutrombopag

Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages...
Approved
Investigational

Cangrelor

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved

Asunaprevir

Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on...
Approved
Investigational
Withdrawn

Abarelix

Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Approved
Investigational
Withdrawn

Telavancin

Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Approved

Cadmium

An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
Experimental
Matched Synonyms: … Cadmium metal ... Cadmium metallicum ... Colloidal cadmium …
Matched Name: … Cadmium …
Matched Iupac: … cadmium …
Matched Description: … It is a metal and ingestion will lead to CADMIUM POISONING. …

Oleoyl chloride

Experimental
Matched Synonyms: … Oleic chloride ... Oleyl chloride ... Oleic acid chloride …
Matched Name: … Oleoyl chloride …
Matched Iupac: … (9Z)-octadec-9-enoyl chloride …

Acetyl chloride

Experimental
Matched Synonyms: … Acetic chloride ... Ethanoyl chloride ... Acetic acid chloride …
Matched Name: … Acetyl chloride …
Matched Iupac: … acetyl chloride …

Methylmethionine chloride

Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.
Experimental
Matched Synonyms: … Methiosulfonium chloride …
Matched Name: … Methylmethionine chloride …
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
Matched Description: … Methylmethionine chloride may be useful in helping the healing of gastric ulcers. …
Matched Categories: … methiosulfonium chloride …

Chloride ion

Experimental
Matched Synonyms: … Chloride ... Chloride(1-) ... Chloride ions …
Matched Name: … Chloride ion …
Matched Iupac: … chloride …

Cuprous chloride

Experimental
Matched Synonyms: … Copper(1+) chloride …
Matched Name: … Cuprous chloride …

Lauroyl chloride

Experimental
Matched Synonyms: … Dodecanoyl chloride ... Lauric acid chloride ... N-dodecanoyl chloride …
Matched Name: … Lauroyl chloride …
Matched Iupac: … dodecanoyl chloride …

Butyl chloride

Vet approved
Matched Synonyms: … n-Butyl chloride ... n-Propylcarbinyl chloride …
Matched Name: … Butyl chloride …

Mercuric chloride

Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a topical antiseptic and disinfectant. Mercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern...
Experimental
Matched Synonyms: … Mercuric chloride ... Mercury(II) chloride ... corrosive mercury chloride …
Matched Name: … Mercuric chloride …
Matched Description: … Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and ... Mercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern medicine …
Matched Categories: … mercuric chloride …

Cholesteryl chloride

Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals.
Experimental
Matched Synonyms: … Cholesterol chloride …
Matched Name: … Cholesteryl chloride …
Matched Description: … Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol …

N-acetylsulfanilyl chloride

ASC has been investigated for the screening of Patients Undergoing Screening or Surveillance Colonoscopy.
Investigational
Matched Synonyms: … 4-(acetylamino)benzenesulfonyl chloride …
Matched Name: … N-acetylsulfanilyl chloride …
Matched Iupac: … 4-acetamidobenzene-1-sulfonyl chloride …

Lithium chloride

Experimental
Matched Name: … Lithium chloride …
Matched Categories: … lithium chloride …

Nolpitantium chloride

Experimental
Matched Name: … Nolpitantium chloride …
Displaying drugs 501 - 525 of 1393 in total