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Displaying drugs 501 - 525 of 771 in total

(3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione

Experimental
Matched Name: … (3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione …

Inositol nicotinate

Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched International brands: … Hexin …
Matched Description: … nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and ... vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and ... Niacin exists in different forms including nicotinic acid, nicotinamide and other derivatives such as …
Matched Categories: … Nicotinic Acid and Derivatives …

{[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid

Experimental
Matched Name: … {[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid …

Allyl-{6-[3-(4-Bromo-Phenyl)-Benzofuran-6-Yloxy]-Hexyl-}-Methyl-Amin

Experimental
Matched Name: … Allyl-{6-[3-(4-Bromo-Phenyl)-Benzofuran-6-Yloxy]-Hexyl-}-Methyl-Amin …
Matched Iupac: … (6-{[3-(4-bromophenyl)-1-benzofuran-6-yl]oxy}hexyl)(methyl)(prop-2-en-1-yl)amine …

Enmetazobactam

Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like [morphine] and …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … FENTANIL HEXAL ... FENTANIL HEXAL AG ... FENTANYL HEXAL S 12UG/H …

Opipramol

Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and …
Matched Products: … OPIPRAMOL HEXAL 50MG ... OPIPRAMOL HEXAL 100MG ... OPIPRAMOL HEXAL 150MG …

Dalosirvat

Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).
Investigational
Matched Synonyms: … 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione …
Matched Description: … Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and …

Xipamide

Experimental
Matched Products: … XIPAMID HEXAL 10MG ... XIPAMID HEXAL 20MG ... XIPAMID HEXAL 40MG …

1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE

Experimental
Matched Name: … 1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE …
Matched Iupac: … propan-2-yl 2-chloro-5-{[(propan-2-yloxy)methanethioyl]amino}benzoate …

Carbimazole

An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Approved
Investigational
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CARBIMAZOL 5MG HEXAL ... CARBIMAZOL 10MG HEXAL …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Mixtures name: … RAMIPRIL HEXAL PL PIR5/6MG ... RAMIPRIL HEXAL PL PIR5/6MG ... RAMIPRIL HEXAL PL PIR5/6MG …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … PIRETANID HEXAL 3MG ... PIRETANID HEXAL 6MG …

5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE

Experimental
Matched Name: … 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …

Pergolide

Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome....
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine ... The drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Products: … PERGOLID HEXAL 1MG ... PERGOLID HEXAL 0.25MG …

Azathioprine

Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … AZATIOPRINA HEXAL ... AZATHIOPRIN HEXAL 75MG ... AZATHIOPRIN HEXAL 100MG …

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Mixtures name: … RAMIPRIL HEXAL PL AM 5/5 ... RAMIPRIL HEXAL PL AM 5/5 ... RAMIPRIL HEXAL PL AM 5/5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and diuretics …
Matched Products: … RAMIPRIL HEXAL ... RAMIPRIL HEXAL AG ... RAMIPRIL HEXAL 5MG …

Moclobemide

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide ... is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA ... Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than …
Matched Categories: … Benzamides and benzamide derivatives ... Benzoates …
Matched Products: … MOCLOBEMID HEXAL 150MG ... MOCLOBEMID HEXAL 300MG ... MOCLOBEMIDE HEXAL TABLET 150mg …

Mirtazapine

Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. ... symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and …
Matched Products: … MIRTAZAPINA HEXAL ... MIRTAZAPINA HEXAL AG ... MIRTAZAPIN HEXAL 15MG …

Methimazole

Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and ... metabolite of the pro-drug [carbimazole], which is an antithyroid medication used in the United Kingdom and …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … THIAMAZOL 5MG HEXAL ... THIAMAZOL 10MG HEXAL ... THIAMAZOL 20MG HEXAL …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... Due to these modifications, it presents a very high potency and comparable side effect profile to the ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … HYDROMORPHON HEXAL 4MG ... HYDROMORPHON HEXAL 8MG ... HYDROMORPHON HEXAL 16MG …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … NIMODIPINA HEXAL ... NIMODIPIN HEXAL 30MG ... Nimodipine HEXAL® 30 mg Film-coated Tablet …

Etavopivat

Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Description: … , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. ... Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension …
Matched Categories: … Alpha and Beta Blocking Agents ... carvedilol and ivabradine ... Calcium-Regulating Hormones and Agents …
Matched Products: … CARVEDILOLO HEXAL ... CARVEDILOL HEXAL 25MG ... CARVEDILOL HEXAL 50MG …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and …
Matched Categories: … moxonidine and diuretics …
Matched Products: … MOXONIDIN HEXAL 0.2MG FILM ... MOXONIDIN HEXAL 0.3MG FILM ... MOXONIDIN HEXAL 0.4MG FILM …

Clopidogrel

Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … HEXYR ... CLOPIDOGREL HEXAL ... Clopidogrel Hexal …
Displaying drugs 501 - 525 of 771 in total