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Displaying drugs 5576 - 5600 of 9101 in total
Cethromycin
Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6-linked aromatic ring system. Cethromycin represents a joint development effort by Abbott Laboratories, Taisho Pharmaceuticals, and Advanced Life Sciences, intended to be marketed under the trade name Restanza for the treatment of community-acquired pneumonia.[L14006, A203369]...
Investigational
Matched Iupac: … (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl] ... oxy}-4-ethyl-3a,7,9,11,13,15-hexamethyl-11-{[3-(quinolin-3-yl)prop-2-en-1-yl]oxy}-tetradecahydro-1H-oxacyclotetradeca …
Matched Description: … Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6- …
Matched Description: … Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6- …
5-N-Allyl-arginine
Experimental
Matched Name: … 5-N-Allyl-arginine …
Matched Iupac: … (E)-[(4S)-4-amino-4-carboxybutyl]({amino[(prop-2-en-1-yl)amino]methylidene})azanium …
Matched Iupac: … (E)-[(4S)-4-amino-4-carboxybutyl]({amino[(prop-2-en-1-yl)amino]methylidene})azanium …
Inosine 5'-sulfate
Investigational
Matched Name: … Inosine 5'-sulfate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}sulfonic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}sulfonic acid …
Chromate ion Cr-51
Experimental
SC-236
SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
Experimental
Investigational
Matched Iupac: … 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Matched Description: … SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been …
Matched Description: … SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been …
TP-271
TP-271 is under investigation in clinical trial NCT02724085 (A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271).
Investigational
Matched Iupac: … yl]-1-methylpyrrolidine-2-carboxamide ... dimethylamino)-4-fluoro-1,8,10a,11-tetrahydroxy-10,12-dioxo-5,5a,6,6a,7,10,10a,12-octahydrotetracen-2- …
M-2698
M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies).
Investigational
Matched Iupac: … 4-{[(1S)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl]amino}quinazoline-8-carboxamide …
AEM-28
AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.
Investigational
BN-201
Investigational
Matched Synonyms: … N-(2-amino-2-oxoethyl)-2-(2-((4-fluorophenethyl)amino)-N-isobutylacetamido)-N-(3-(2-oxopyrrolidin-1-yl ... Glycinamide, n-(2-(2-fluorophenyl)ethyl)glycyl-n-(2-methylpropyl)glycyl-n2-(3-(2-oxo-1-pyrrolidinyl)propyl ... )propyl)acetamide N-({Carbamoylmethyl-[3-(2-oxo-pyrrolidin-1-yl)propyl}-carbamoyl}-methyl)-2-[2-(2-fluorophenyl …
Matched Iupac: … N-(carbamoylmethyl)-2-(2-{[2-(2-fluorophenyl)ethyl]amino}-N-(2-methylpropyl)acetamido)-N-[3-(2-oxopyrrolidin …
Matched Iupac: … N-(carbamoylmethyl)-2-(2-{[2-(2-fluorophenyl)ethyl]amino}-N-(2-methylpropyl)acetamido)-N-[3-(2-oxopyrrolidin …
AD-214
Investigational
Matched Synonyms: … Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 …
TN-201
TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
7-methyl-guanosine-5'-triphosphate-5'-guanosine
Experimental
Matched Name: … 7-methyl-guanosine-5'-triphosphate-5'-guanosine …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-5-({[({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9-ylium ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-5-({[({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9-ylium ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan …
19-Nor-5-androstenedione
19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone once metabolized in vivo. It is regulated in the United States as a schedule III controlled substance, and prohibited by the World Anti-Doping Agency for use in competitive sports.
Experimental
Illicit
Matched Synonyms: … estr-5-ene-3,17-dione …
Matched Name: … 19-Nor-5-androstenedione …
Matched Description: … 19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone …
Matched Name: … 19-Nor-5-androstenedione …
Matched Description: … 19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Iupac: … }prop-2-enamide ... N-{3-[(2-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl …
Matched Description: … more pronounced clinical benefits as compared to agents targeting single pathways (e.g. interleukin-6 …
Matched Description: … more pronounced clinical benefits as compared to agents targeting single pathways (e.g. interleukin-6 …
Coenzyme A
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of...
Investigational
Nutraceutical
Matched Synonyms: … 3'-phosphoadenosine-(5')diphospho(4')pantatheine …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tyrosyladenylate
Experimental
Matched Synonyms: … 5'-O-(L-Tyrosylsulfamoyl)adenosine …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) …
Isoflavone
Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa . Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram . The main soy isoflavones are mostly...
Experimental
Matched Description: … Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Interferon alfa-2c
Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma).
Investigational
Chiglitazar
Chiglitazar is under investigation in clinical trial NCT06125587 (Chiglitazar/metformin in Non-obese Women With PCOS).
Investigational
Matched Synonyms: … (2s)-3-(4-(2-carbazol-9-ylethoxy)phenyl)-2-(2-(4-fluorobenzoyl)anilino)propanoic acid ... L-tyrosine, o-(2-(9h-carbazol-9-yl)ethyl)-n-(2-(4-fluorobenzoyl)phenyl)- ... O-(2-(9h-carbazol-9-yl)ethyl)-n-(2-(4-fluorobenzoyl)phenyl)-l-tyrosine …
Matched Salts cas: … 2390374-10-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 2390374-10-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
PH-284
PH-284 belongs to a new family of new chemical entities called vomeropherins. Vomeropherins are self-administered by the patient with a metered nasal spray, or nasal aerosol device so that they can bind to peripheral chemosensory receptors in the nasal passages. This binding produces neural impulses that are transmitted by specific...
Investigational
GTS-21
GTS-21 (also known as DMBX-A), is a novel, small-molecule, orally active and selective alpha-7 nicotinic acetylcholine (nACh) receptor agonist that has demonstrated memory and cognition enhancement activity in human clinical trials. Athenagen licensed the exclusive rights to the compound and a related library of analogs as part of the acquisition...
Investigational
T-2000
T2000 has been used in trials studying the treatment of Myoclonus and Essential Tremor.
Investigational
IO-202
IO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4). It is being investigated in cancers.
Investigational
HPA-23
HPA-23 is an investigational antiviral compound.
Investigational
Matched Iupac: … henicosatungsten(6+) nonaantimony(3+) disodium(2+) heptadecaammonium hexaoctacontaoxidandiide …
LP-284
Investigational
Displaying drugs 5576 - 5600 of 9101 in total