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Displaying drugs 5601 - 5625 of 11755 in total

Alaproclate

Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal studies. Alaproclate has also been found to act as a non-competitive NMDA receptor antagonist although without discriminative...
Experimental
Matched Description: … Alaproclate has also been found to act as a non-competitive NMDA receptor antagonist although without …

Amitifadine

Investigational

Atipamezole

Atipamezole is a synthetic α2 adrenoceptor antagonistused to reverse the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. It has also been undergone research as a potential anti-Parkinsonian drug for humans.
Investigational
Vet approved
Matched Description: … It has also been undergone research as a potential anti-Parkinsonian drug for humans. ... Atipamezole is a synthetic α2 adrenoceptor antagonistused to reverse the sedative and analgesic effects …

Bufotenine

A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.
Experimental
Illicit
Matched Description: … Bufotenin has been used as a tool in CNS studies and misused as a psychedelic. ... A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, …
Matched Categories: … Monoamine Oxidase A Substrates …

Endostatin

Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Eprinomectin

Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Isepamicin

Experimental
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …

Bekanamycin

Experimental
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …

Maritime pine extract

Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …

Aminooxyacetic acid

A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Experimental
Matched Description: … A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of …

4-Amino Hexanoic Acid

Experimental

Invert sugar

Invert sugar is obtained from sugar cane when this is treated with dilute acid or with the invertase enzyme. It is formed by an equal amount of glucose and fructose. It differentiates from sugar cane in the rotation of the polarized light, which in the case of invert sugar it...
Experimental
Matched Description: … [A32124] Invert sugar is FDA approved since 1988 as a safe substance (GRAS). …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Exisulind

Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Emoxypine

Emoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure).
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Trodusquemine

Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B. It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models .
Investigational
Matched Iupac: … 3-aminopropyl)amino]butyl}amino)propyl]amino}-4-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits …

Fluprednidene acetate

Fluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties.
Experimental
Matched Iupac: … dihydroxy-9a,11a-dimethyl-2-methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Fluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties. …

Fluocortolone pivalate

Experimental
Matched Iupac: … fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …

Centhaquine

Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock).
Investigational
Matched Description: … Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a …

Stepronin

Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
Experimental
Matched Description: … Strepronin is a mucolytic drug. ... A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties …

AMPCPR

Experimental

AdPEDF

AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD). It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors.
Investigational

ANX-510

ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of the widely used cancer chemotherapy, 5-fluorouracil (5-FU). CoFactor use with 5-FU is being evaluated in clinical trials in first line treatment of metastatic colorectal cancer.
Investigational
Matched Description: … ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce …

ACA 125

An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas. This new concept of oncological immunotherapy consists of an attempt to trigger the immune system of the host...
Investigational
Matched Description: … To create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow …

ATN-161

ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. This approach targeting both the tumor vasculature and the cancer cells themselves, may be effective...
Investigational
Matched Description: … ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. ... inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a ... range of different cancers, the therapeutic benefit of ATN-161 is expected to extend to a variety of …

AVN-944

AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism, DNA replication, apoptosis and cell cycle control. AVN944 has been associated with cancer cell death in clinical trials. It is...
Investigational
Matched Description: … AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins …
Displaying drugs 5601 - 5625 of 11755 in total