Displaying drugs 551 - 575 of 1458 in total
Avanafil
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Edoxaban
Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Afatinib
Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved
Neratinib
Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Approved
Investigational
Indomethacin
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Delafloxacin
Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, among others. It was approved in June 2017 under the trade name Baxdela for use in the treatment of...
Approved
Investigational
Lusutrombopag
Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages...
Approved
Investigational
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Asunaprevir
Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on...
Approved
Investigational
Withdrawn
Esomeprazole
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Salts name: … Esomeprazole magnesium dihydrate …
Abarelix
Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Approved
Investigational
Withdrawn
Telavancin
Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Approved
Barium
Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease.
Investigational
Matched Name: … Barium …
Matched Iupac: … barium …
Matched Description: … Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease. …
Matched Iupac: … barium …
Matched Description: … Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease. …
Oleoyl chloride
Experimental
Matched Synonyms: … Oleic chloride ... Oleyl chloride ... Oleic acid chloride …
Matched Name: … Oleoyl chloride …
Matched Iupac: … (9Z)-octadec-9-enoyl chloride …
Matched Name: … Oleoyl chloride …
Matched Iupac: … (9Z)-octadec-9-enoyl chloride …
Acetyl chloride
Experimental
Matched Synonyms: … Acetic chloride ... Ethanoyl chloride ... Acetic acid chloride …
Matched Name: … Acetyl chloride …
Matched Iupac: … acetyl chloride …
Matched Name: … Acetyl chloride …
Matched Iupac: … acetyl chloride …
Methylmethionine chloride
Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.
Experimental
Matched Synonyms: … Methiosulfonium chloride …
Matched Name: … Methylmethionine chloride …
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
Matched Description: … Methylmethionine chloride may be useful in helping the healing of gastric ulcers. …
Matched Categories: … methiosulfonium chloride …
Matched Name: … Methylmethionine chloride …
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
Matched Description: … Methylmethionine chloride may be useful in helping the healing of gastric ulcers. …
Matched Categories: … methiosulfonium chloride …
Chloride ion
Experimental
Matched Synonyms: … Chloride ... Chloride(1-) ... Chloride ions …
Matched Name: … Chloride ion …
Matched Iupac: … chloride …
Matched Name: … Chloride ion …
Matched Iupac: … chloride …
Cuprous chloride
Experimental
Matched Synonyms: … Copper(1+) chloride …
Matched Name: … Cuprous chloride …
Matched Name: … Cuprous chloride …
Lauroyl chloride
Experimental
Matched Synonyms: … Dodecanoyl chloride ... Lauric acid chloride ... N-dodecanoyl chloride …
Matched Name: … Lauroyl chloride …
Matched Iupac: … dodecanoyl chloride …
Matched Name: … Lauroyl chloride …
Matched Iupac: … dodecanoyl chloride …
Butyl chloride
Vet approved
Matched Synonyms: … n-Butyl chloride ... n-Propylcarbinyl chloride …
Matched Name: … Butyl chloride …
Matched Name: … Butyl chloride …
Mercuric chloride
Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a topical antiseptic and disinfectant. Mercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern...
Experimental
Matched Synonyms: … Mercuric chloride ... Mercury(II) chloride ... corrosive mercury chloride …
Matched Name: … Mercuric chloride …
Matched Description: … Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and ... Mercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern medicine …
Matched Categories: … mercuric chloride …
Matched Name: … Mercuric chloride …
Matched Description: … Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and ... Mercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern medicine …
Matched Categories: … mercuric chloride …
Cholesteryl chloride
Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals.
Experimental
Matched Synonyms: … Cholesterol chloride …
Matched Name: … Cholesteryl chloride …
Matched Description: … Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol …
Matched Name: … Cholesteryl chloride …
Matched Description: … Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol …
N-acetylsulfanilyl chloride
ASC has been investigated for the screening of Patients Undergoing Screening or Surveillance Colonoscopy.
Investigational
Matched Synonyms: … 4-(acetylamino)benzenesulfonyl chloride …
Matched Name: … N-acetylsulfanilyl chloride …
Matched Iupac: … 4-acetamidobenzene-1-sulfonyl chloride …
Matched Name: … N-acetylsulfanilyl chloride …
Matched Iupac: … 4-acetamidobenzene-1-sulfonyl chloride …
Lithium chloride
Experimental
Matched Name: … Lithium chloride …
Matched Categories: … lithium chloride …
Matched Categories: … lithium chloride …
Displaying drugs 551 - 575 of 1458 in total