Displaying drugs 551 - 575 of 696 in total
Rotigotine
Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Synonyms: … (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol …
Matched Description: … restless legs syndrome (RLS) in Europe and the United States. ... (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and ... It was approved by the European Medicines Agency in 2006 and by the FDA in 2007. …
Matched Categories: … Naphthalenes …
Matched Description: … restless legs syndrome (RLS) in Europe and the United States. ... (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and ... It was approved by the European Medicines Agency in 2006 and by the FDA in 2007. …
Matched Categories: … Naphthalenes …
2-aminoethyl naphthalen-1-ylacetate
Experimental
Matched Name: … 2-aminoethyl naphthalen-1-ylacetate …
Matched Iupac: … 2-aminoethyl 2-(naphthalen-1-yl)acetate …
Matched Iupac: … 2-aminoethyl 2-(naphthalen-1-yl)acetate …
(S)-2-{Methyl-[2-(Naphthalene-2-Sulfonylamino)-5-(Naphthalene-2-Sulfonyloxy)-Benzoyl]-Amino}-Succinicacid
Experimental
Matched Name: … (S)-2-{Methyl-[2-(Naphthalene-2-Sulfonylamino)-5-(Naphthalene-2-Sulfonyloxy)-Benzoyl]-Amino}-Succinicacid …
Matched Iupac: … (2S)-2-{N-methyl-1-[2-(naphthalene-2-sulfonamido)-5-[(naphthalene-2-sulfonyl)oxy]phenyl]formamido}butanedioic …
Matched Iupac: … (2S)-2-{N-methyl-1-[2-(naphthalene-2-sulfonamido)-5-[(naphthalene-2-sulfonyl)oxy]phenyl]formamido}butanedioic …
Indralin
Investigational
Matched Synonyms: … 2-thiophenecarboxylic acid, 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen ... 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen-1-yl)-2-thiophenecarboxylic …
Desloratadine
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter ... It is the active descarboethoxy metabolite of loratidine (a second generation histamine). …
Matched Categories: … Loratadine and derivatives ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … HISTALINE ... HISTALINE ® 0.5 MG / ML JARABE …
Matched Categories: … Loratadine and derivatives ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … HISTALINE ... HISTALINE ® 0.5 MG / ML JARABE …
8-anilinonaphthalene-1-sulfonic acid
Experimental
Matched Synonyms: … 8-Anilino-1-naphthalene sulfonic acid …
Matched Iupac: … 8-(phenylamino)naphthalene-1-sulfonic acid …
Matched Categories: … Indicators and Reagents ... Naphthalenes …
Matched Iupac: … 8-(phenylamino)naphthalene-1-sulfonic acid …
Matched Categories: … Indicators and Reagents ... Naphthalenes …
Levobunolol
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Synonyms: … (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Naphthalenes …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Naphthalenes …
Schisandra chinensis fruit
Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Five-flavoured Seed …
(2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide
Experimental
Matched Name: … (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide …
Matched Iupac: … (2R)-N-hydroxy-3-(naphthalen-2-yl)-2-(naphthalene-2-sulfonamido)propanamide …
Matched Iupac: … (2R)-N-hydroxy-3-(naphthalen-2-yl)-2-(naphthalene-2-sulfonamido)propanamide …
NNC-55-0396 free base
NNC-55-0396 is a T-type Ca(2+) channel inhibitor.
Investigational
Matched Synonyms: … ((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Synonyms: … (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Naphthalenes …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Naphthalenes …
Diazolidinylurea
Approved
Experimental
Matched Synonyms: … Diazolidinyl urea ... N,N'-Bis(hydroxymethyl) urea ... N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N,N'-bis(hydroxymethyl)urea …
Matched Iupac: … 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea …
Matched Categories: … Increased Histamine Release …
Matched Iupac: … 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea …
Matched Categories: … Increased Histamine Release …
WIN 55212-2
WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of...
Experimental
Matched Synonyms: … (2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl …
Matched Iupac: … (11R)-2-methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12 …
Matched Description: … It activates p42 and p44 MAP kinase via receptor-mediated signaling. …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Matched Iupac: … (11R)-2-methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12 …
Matched Description: … It activates p42 and p44 MAP kinase via receptor-mediated signaling. …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Synonyms: … 4-(6-Methoxy-2-naphthalenyl)-2-butanone …
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid
Experimental
Matched Name: … 3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid …
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid …
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid …
Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine
Experimental
Matched Name: … Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine …
Matched Iupac: … 6-[(1R,2R)-2-phenylcyclopropyl]naphthalene-2-carboximidamide …
Matched Iupac: … 6-[(1R,2R)-2-phenylcyclopropyl]naphthalene-2-carboximidamide …
8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide
Experimental
Matched Name: … 8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide …
Matched Iupac: … 8-[(pyrimidin-2-yl)amino]naphthalene-2-carboximidamide …
Matched Iupac: … 8-[(pyrimidin-2-yl)amino]naphthalene-2-carboximidamide …
6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID …
Matched Iupac: … 6-[difluoro(phosphono)methyl]naphthalene-2-carboxylic acid …
Matched Iupac: … 6-[difluoro(phosphono)methyl]naphthalene-2-carboxylic acid …
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated ... [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and ... the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated ... [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and ... the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
MPT-0L055
Investigational
Matched Synonyms: … 4-(((3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino)methyl)-n-3-pyridinylbenzamide ... Benzamide, 4-(((3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino)methyl)-n-3-pyridinyl- …
Karaya gum
Karaya gum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Sterculia urens resin …
Matched Categories: … Alimentary Tract and Metabolism ... Equipment and Supplies ... Increased Histamine Release …
Matched Categories: … Alimentary Tract and Metabolism ... Equipment and Supplies ... Increased Histamine Release …
KUS-121 free acid
Investigational
Matched Synonyms: … 4-Amino-3-[[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]azo]naphthalene-1-sulfonic acid …
Matched Iupac: … 4-amino-3-[(1E)-2-[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]diazen-1-yl]naphthalene-1-sulfonic acid …
Matched Iupac: … 4-amino-3-[(1E)-2-[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]diazen-1-yl]naphthalene-1-sulfonic acid …
Arotinoid acid
Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
Experimental
Matched Synonyms: … (E)-4-(2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl)benzoic acid …
Imidurea
Imidurea is an antimicrobial preservative used in cosmetics. It acts as a formaldehyde releaser.
Approved
Experimental
Matched Synonyms: … Imidazolidinyl urea …
Matched Iupac: … 2,5-dioxoimidazolidin-4-yl]-1-[({[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoyl}amino)methyl]urea …
Matched Categories: … Increased Histamine Release …
Matched Iupac: … 2,5-dioxoimidazolidin-4-yl]-1-[({[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoyl}amino)methyl]urea …
Matched Categories: … Increased Histamine Release …
Displaying drugs 551 - 575 of 696 in total