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Displaying drugs 551 - 575 of 1241 in total
Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only...
Investigational
Nutraceutical
Matched Name: … Tyramine
Matched Description: … compound and trace amine derived from the amino acid tyrosine. ... Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine ... Tyramine acts by inducing the release of catecholamine. …
Matched Salts name: … Tyramine hydrochloride …
Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis...
Investigational
Matched Name: … Tyrosinase
Matched Description: … in mammals, thus causing undesired browning of fruits and vegetables and diseases resulting from melanin ... form and plays a critical role in regulating the process of melanin biosynthesis (also known as melanogenesis ... [A231829, A231839] It is recognized as being the main enzyme responsible for enzymatic browning and melanogenesis …
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Synonyms: … L-tryptophan amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein ... TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -3-cyclohexyl-d-alanyl-d-arginyl-d-arginyl-d-arginyl-d-glutaminyl-d-arginyl- ... D-arginine, 4-benzoyl-d-phenylalanyl-d-seryl-d-tryptophyl-d-seryl-2,3,4,5,6-pentafluoro-d-phenylalanyl …
Matched Categories: … Protein Tyrosine Phosphatases ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intracellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … L-tyrosine-l-serine-l-leucine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … (-)-menthol (+/-)-1-propylene glycol carbonate ... Fema no. 3806, 1-propylene glycol carbonate ... 2-hydroxypropyl ((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) carbonate
Matched Name: … (-)-menthol 1-propylene glycol carbonate
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … factor 21 (98-arginine,171-glycine,180-glutamic acid) (human mutant clone amg876) ... (human), dimer ... (ggggs)3 fusion protein with fibroblast growth factor 21 (98-arginine,171-glycine,180-glutamic acid) …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Approved
Vet approved
Withdrawn
Matched Synonyms: … Chlorphenesin carbamate ... 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate ... 3-(4-chlorophenoxy)-1,2-propanediol-1-carbamate
Matched Name: … Chlorphenesin carbamate
Matched Iupac: … 3-(4-chlorophenoxy)-2-hydroxypropyl carbamate
Zanolimumab is a fully human monoclonal antibody directed against CD4.
Investigational
Matched Synonyms: … Humax-cd4 ... IMMUNOGLOBULIN, ANTI-(HUMAN CD4 ANTIGEN) (HUMAN MONOCLONAL 6G5 HEAVY CHAIN), DISULPHIDE WITH HUMAN MONOCLONAL …
Matched Description: … Zanolimumab is a fully human monoclonal antibody directed against CD4. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... PGs contribute to inflammation and pain signalling. …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac potassium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... diclofenac and antiinfectives ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM
Experimental
Matched Synonyms: … 3-Nitro-L-tyrosine
Matched Name: … 3-nitro-L-tyrosine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 1-hydroperoxy-L-tryptophan
Experimental
Matched Name: … 7-Aza-L-tryptophan
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched International brands: … HuMax-EGFR ... HuMax-EGFR-2F8 ... HuMax-EGFR, 2F8 …
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. ... Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … N-Carbamyl-L-glutamate ... Carbamino-L-glutamic acid ... N-Carbamoyl-L-Glutamic Acid …
Matched Description: … Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins …
Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Synonyms: … Choline carbamate
Matched Iupac: … 2-(trimethylazaniumyl)ethyl carbamate
Matched Description: … Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and
Matched Categories: … Antiglaucoma Preparations and Miotics …
Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Pteroyl-L-glutamate ... Pteroyl-L-glutamic acid ... N-pteroyl-L-glutamic acid …
Matched Description: … As humans are unable to synthesize folic acid endogenously, diet and supplementation is necessary to ... cofactor for enzymes involved in DNA and RNA synthesis. ... Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential …
Matched Mixtures name: … Isotonix Advanced B-complex Vitamins With Potassium and Magnesium ... Chela Potassium Plus ... Potassium W Folic Acid Tab …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... iron, multivitamins and folic acid ... ferrous sulfate and folic acid …
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … 2-(difluoromethyl)ornithine
Matched Description: … hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells. ... for human African trypanosomiasis. ... [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA …
Matched Categories: … Ornithine Decarboxylase Inhibitors ... Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Experimental
Matched Synonyms: … Tyramine sulfate …
Matched Name: … Tyramine O-sulfate …
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS ... CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis ... factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus …
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-Nim-benzyl-histidyl-L-leucyl-L-arginyl-L-proline ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin
Matched Categories: … Adrenal Cortex Hormones ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … (-)-(s)-2-acetamido-n-(3,4-dihydroxyphenethyl)-4-(methylthio)butyramide bis(ethyl carbonate) (ester) …
Matched Iupac: … 5-{2-[(2S)-2-acetamido-4-(methylsulfanyl)butanamido]ethyl}-2-[(ethoxycarbonyl)oxy]phenyl ethyl carbonate
Experimental
Matched Name: … Ndelta-(N'-Sulphodiaminophosphinyl)-L-Ornithine
Displaying drugs 551 - 575 of 1241 in total