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Displaying drugs 551 - 575 of 1089 in total

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Antidote for Acetaminophen Overdose ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Matched Products: … SIRAN FORTE ... ANCARE SOLUTION FOR IV INFUSION 100MG/ML ... HIDONAC SOLUTION FOR INFUSION 5 g/25 ml …

Erenumab

Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the ... Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and ... first and only FDA approved treatment specifically developed to prevent migraine by blocking the CGRP …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AIMOVIG (140 MG/ML SOLUTION FOR INJECTION) ... AIMOVIG (70 MG/ML SOLUTION FOR INJECTION) ... AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication ... first approved for use in the United States in 2001. ... [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases ... formoterol and mometasone ... formoterol and budesonide ... formoterol and fluticasone …
Matched Products: … FORMO-ARISTO 12UG ... Foradil Dry Powder Capsules for Inhalation ... FORADIL CAPSULE FOR INHALATION 12 mcg/capsule …

Pertuzumab

Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Description: … It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … Perjeta 420 mg concentrate for solution for infusion ... PERJETA CONCENTRATE FOR SOLUTION FOR INFUSION 420MG/14ML ... PHESGO SOLUTION FOR SUBCUTANEOUS INJECTION 600 MG/600 MG / 10 ML …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Azacitidine For ... Vidaza powder for suspension for injection 100mg/vial ... AZADINE POWDER FOR SUSPENSION FOR INJECTION 100MG/VIAL …

Sodium chloride

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … Accusol 35 Solution for Haemofiltration, Haemodialysis and Haemodiafiltration ... Accusol 35 Potassium 4 mmol/l Solution for Haemofiltration, Haemodialysis and Haemodiafiltration ... ELECTRAL FORTE GRANULES …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Walgreens Infants and Childrens Saline Nasal ... DILUTE FOR EPOPROSTENOL FOR INTRAVENOUS INJECTION ... Sodium Chloride for Irrigation …

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma ... Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... and marketed under the brand name Nucala by GlaxoSmithKline. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs for Obstructive Airway Diseases …
Matched Products: … NUCALA POWDER FOR SOLUTION FOR INJECTION 100mg ... Nucala 100mg Powder for Solution for Injection ... NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML …

Atezolizumab

Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted...
Approved
Investigational
Matched Description: … Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing ... [L7489] In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for ... [A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 840MG/14ML ... Tecentriq 60mg/ml Concentrate for Solution for Infusion ... TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 1200 MG/ 20 ML …

Aflibercept

Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Description: … the treatment of retinopathy of prematurity in preterm infants in February 2023 and for the treatment ... and February 2013, respectively. ... the treatment of metastatic colorectal cancer, and it was approved by the FDA and EMA in August 2012 …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Zaltrap 25mg/ml Concentrate for Solution for Infusion ... ZALTRAP CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/ML ... EYLEA SOLUTION FOR INJECTION IN VIAL 2MG …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … (XLH), which is a rare, inherited form of rickets. ... It causes impaired bone growth and development in children and adolescents and issues with bone mineralization ... This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … CRYSVITA 10 MG SOLUTION FOR INJECTION ... CRYSVITA 20 MG SOLUTION FOR INJECTION ... CRYSVITA 30 MG SOLUTION FOR INJECTION …

Levodropropizine

Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Investigational
Matched Description: … Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … LEVOZOPIN FORT 60MG/5ML ŞURUP, 75 ML ... LEVOPRONT FORT 60 MG/5 ML ŞURUP, 75 ML ... LEVOSOL FORT 60 MG / 5 ML ŞURUP, 75 ML …

Tirzepatide

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Dual GIP/GLP-1 agonists gained increasing attention as new therapeutic agents for glycemic and weight control as they demonstrated better glucose control and weight loss compared to selective GLP-1 receptor agonists in preclinical and clinical trials....
Approved
Investigational
Matched Description: … Dual GIP/GLP-1 agonists gained increasing attention as new therapeutic agents for glycemic and weight ... for this indication. ... the treatment of adults with type 2 diabetes, making it the first and only GIP and GLP-1 receptor agonist …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Mounjaro 2.5 mg solution for injection in pre-filled pen ... Mounjaro 5 mg solution for injection in pre-filled pen ... Mounjaro 7.5 mg solution for injection in pre-filled pen …

(10R)-10-formyl-5,8,10-trideazafolic acid

Experimental
Matched Name: … (10R)-10-formyl-5,8,10-trideazafolic acid …

Alglucosidase alfa

Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Description: … It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... residue mature polypeptide chain, and a total mass of approximately 109,000 daltons, including carbohydrates …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … Myozyme Powder for Solution for Injection ... (Alglucosidase alfa) 50mg Powder for Solution for Infusion …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Irinotecan is a topoisomerase inhibitor used for chemotherapy. ... Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IRITEC CONCENTRATE FOR SOLUTION FOR INFUSION 40mg/2ml ... IRITEC CONCENTRATE FOR SOLUTION FOR INFUSION 100mg/5ml ... Inotecam 20mg/ml Concentrate for Solution for Infusion …

Luspatercept

Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...
Approved
Investigational
Matched Description: … in which late-stage erythropoiesis is defective, such as beta thalassemia and other myelodysplastic ... erythropoiesis, in contrast to typical erythropoiesis-stimulating agents (ESAs), such as [darbepoetin alfa] and ... [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins …
Matched Products: … Reblozyl 25 mg powder for solution for injection ... Reblozyl 75 mg powder for solution for injection …

Adalimumab

Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Description: … This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered ... arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. ... [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … IDACIO SOLUTION FOR INJECTION FOR PAEDIATRIC USE 40MG/0.8ML VIAL ... IDACIO solution for Injection for paediatric use 40mg/0.8ml ... HUMIRA SOLUTION FOR INJECTION …

Fludarabine

Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … FLUDARABINE PHOSPHATE POWDER FOR SOLUTION FOR INJECTION/ INFUSION USP ... Fludarabine Kabi 50mg Lyophilized Powder for Solution for Injection or Infusion ... Fludarabine Sandoz 50 mg/2ml concentrate for solution for injection or infusion …

Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside …
Matched Iupac: … [(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …
Matched Products: … Streptomycin for Injection USP ... STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial …

Tozinameran

The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Description: … [L26956] Fact sheets for caregivers, recipients, and healthcare providers are now available. ... Comirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older. ... 9, 2020[L26671] for active immunization against SARS-CoV-2. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Comirnaty 3mcg Concentrate for Dispersion for Injection ... Comirnaty Omicron XBB.1.5 10 micrograms/dose Dispersion for Injection ... Comirnaty Omicron XBB.1.5 30 micrograms/dose Dispersion for Injection …

Styphnolobium japonicum flower bud

Styphnolobium japonicum flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Products: … BARAMO for O ily Scalp ... BARAMO for Normal Scalp ... BARAMO Scalp Serum for Normal Scalp …

Pegaspargase

Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia. Asparagine is an amino acid that is vital for cell survival. In humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia...
Approved
Investigational
Matched Description: … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine ... reducing immune detection, and it also increases the half-life of L-asparaginase. ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ONCASPAR POWDER FOR SOLUTION FOR INJECTION/INFUSION 750 U/ML ... Oncaspar 750 U/ml powder for solution for injection/infusion …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … HYCAMTIN (POWDER FOR SOLUTION FOR INFUSION) ... TOCANTIN POWDER FOR SOLUTION FOR INFUSION 4MG ... TOCANTIN POWDER FOR SOLUTION FOR INFUSION 4 MG/VIAL …

Phellodendron amurense bark

Phellodendron amurense bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Products: … Jayeonbi Secret Care Mist for Lady Y-zone Mist ... Jayeonbi Secret Care Mist for Men Y-zone Mist ... JAYEONBI Secret Care Mist For Lady Y-zone Mist …

Sarilumab

Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL-6. Sarilumab was developed by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed...
Approved
Investigational
Matched Description: … soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL ... in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe rheumatoid ... human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … KEVZARA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG ... KEVZARA Solution for Injection in Pre-filled Pen 150mg ... KEVZARA Solution for Injection in Pre-filled Pen 200mg …
Displaying drugs 551 - 575 of 1089 in total